Results 171 to 180 of about 85,056 (307)

PKCε Contributes to Remifentanil-Induced Hyperalgesia Via Downregulating Mu-Opioid Receptor in Rat Dorsal Root Ganglion Neurons

, 2022
Yanmei Chen, XiaoE Wang, Wenhui Wang, Ping Yu, Linzhi Li, Guoya Luo, Gaijiao Liu, Xiao Li, Yu Chen, Yuan Chen, Yu Cui   +10 more
openalex   +1 more source

Cross-Talk of Toll-Like Receptor 5 and Mu-Opioid Receptor Attenuates Chronic Constriction Injury-Induced Mechanical Hyperalgesia through a Protein Kinase C Alpha-Dependent Signaling [PDF]

, 2021
Ching yun Chang, Hung-Kai Liu, Chao‐Bin Yeh, Minglin Yang, Wen‐Chieh Liao, Chiung‐Hui Liu, To-Jung Tseng   +6 more
openalex   +1 more source

Altered Sigmoid Mucosal Innervation and Mast Cell Proximity to Sensory Nerve Fibers Are Associated With Symptom Severity in Patients With Irritable Bowel Syndrome

Neurogastroenterology &Motility, Volume 37, Issue 12, December 2025.
3D imaging of nerve fibers and mast cells double‐labeled with antibodies against Substance P (SP, red) and tryptase (green) on CLARITY‐cleared human sigmoid colonic mucosal biopsies from an IBS patient. (A). Their spatial proximity was computationally quantified using Imaris 9.7 software (B), which demonstrated a significant positive correlation with ...
Pu‐Qing Yuan, Michael Nash, Tao Li, Swapna Mahurkar‐Joshi, Jessica Sohn, Ariela Khandadash, Yvette Taché, Lin Chang   +7 more
wiley   +1 more source

Prescription Opioid Misuse and the Perceived Likelihood of Future Suicidal Behavior: Considering the Role of Suicide Capability Dimensions

Suicide and Life-Threatening Behavior, Volume 55, Issue 6, December 2025.
ABSTRACT Introduction In the past two decades, suicide attempts and deaths involving prescription opioids have sharply increased. Research is needed to understand how prescription opioid misuse may increase suicide risk. Contemporary suicide theories suggest opioid use may increase suicide capability by increasing pain tolerance, altering fears related
Zachary T. DeMoss, Matthew T. Tull, Kim L. Gratz   +2 more
wiley   +1 more source

Effects of Intrathecally Administered Nociceptin, and Opioid Receptor-like1Receptor Agonist, and N-methyl-D-aspartate Receptor Antagonistst on the Thermal Hyperalgesia Induced by Partial Sciatic Nerve Injury in the Rat  [PDF]

, 1997
Tatsuo Yamamoto, Natsuko Nozaki‐Taguchi   +1 more
openalex   +1 more source

Effect of Gabapentin Administered With Prednisolone, Ciclosporin or a Placebo on Clinical Outcomes and Motor Activity in Cats With Atopic Skin Syndrome: A Prospective, Blinded, Placebo‐Controlled Study

Veterinary Dermatology, Volume 36, Issue 6, Page 814-824, December 2025.
Background: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Jeanne Morency, Éric Troncy, Aliénor Delsart, Colombe Otis, Jérôme R. E. Del Castillo, Andrea Gonzales, Jason Ross, Maxim Moreau, Jean‐Pierre Pelletier, Johanne Martel‐Pelletier, Frédéric Sauvé   +10 more
wiley   +1 more source

Cerebral Activation during Von Frey Filament Stimulation in Subjects with Endothelin-1-Induced Mechanical Hyperalgesia: A Functional MRI Study [PDF]

, 2013
Guy Hans, E. Vandervliet, Kristof Deseure, Paul M. Parizel   +3 more
openalex   +1 more source

Muscle regeneration is improved by hot water immersion but unchanged by cold following a simulated musculoskeletal injury in humans

The Journal of Physiology, Volume 603, Issue 23, Page 7603-7625, December 1, 2025.
Abstract figure legend Thirty‐four participants underwent muscle damage (electrically stimulated eccentric contractions) triggering regenerative processes following myofiber necrosis. Participants were treated for 10 days cold (CWI) (15 min, 12{degree sign}C), thermoneutral (TWI) (30 min, 32{degree sign}C) or hot (HWI) (60 min, 42{degree sign}C) water ...
Valentin Dablainville, Adèle Mornas, Tom Normand‐Gravier, Maha Al‐Mulla, Emmanouil Papakostas, Bruno Olory, Theodorakys Marin Fermin, Frantzeska Zampeli, Nelda Nader, Marine Alhammoud, Freya Bayne, Anthony M. J. Sanchez, Marco Cardinale, Robin Candau, Henri Bernardi, Sébastien Racinais   +15 more
wiley   +1 more source

The 100 top-cited studies on postoperative hyperalgesia in the last 30 years: a bibliometric analysis [PDF]

, 2021
Tianyao Zhang, Xiaochu Wu, Ye Yu, Jun Ma, Cheng Zhou, Peng Liang, Bin Liu   +6 more
openalex   +1 more source

Acute sleep deprivation induces hyperalgesia through P2X4-mediated microglial activation in mice. [PDF]

Eur J Med Res
Huang S, Cheng W, Lai P, Liu X, Peng S, Yang X, Du X.   +6 more
europepmc   +1 more source