Results 171 to 180 of about 98,039 (356)

Psychophysical changes after total sleep deprivation and experimental muscle pain

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Sleep disturbances exacerbate chronic pain, increase psychological load, and increase inflammation. Delayed onset muscle soreness (DOMS) mimics aspects of chronic pain, predominantly affecting peripheral pain mechanisms, while experimental sleep provocations have been shown to impact central pain mechanisms.
Emma Hertel, Elaxmi Sathiyalingam, Linea Pilgaard, Simone Juline Brommann, Rocco Giordano, Kristian Kjær‐Staal Petersen   +5 more
wiley   +1 more source

Effects of Intrathecally Administered Nociceptin, and Opioid Receptor-like1Receptor Agonist, and N-methyl-D-aspartate Receptor Antagonistst on the Thermal Hyperalgesia Induced by Partial Sciatic Nerve Injury in the Rat [PDF]

, 1997
Tatsuo Yamamoto, Natsuko Nozaki‐Taguchi   +1 more
openalex   +1 more source

Antiallodynic and antihyperalgesic activities of zerumbone via the suppression of IL-1β, IL-6, and TNF-α in a mouse model of neuropathic pain

Journal of Pain Research, 2017
Banulata Gopalsamy, Ahmad Akira Omar Farouk, Tengku Azam Shah Tengku Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perimal Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang ...
Gopalsamy B, Farouk AAO, Tengku Mohamad TAS, Sulaiman MR, Perimal EK   +4 more
doaj  

Mispositioned Neurokinin-1 Receptor-Expressing Neurons Underlie Heat Hyperalgesia in Disabled-1 Mutant Mice. [PDF]

, 2019
Reelin (Reln) and Disabled-1 (Dab1) participate in the Reln-signaling pathway and when either is deleted, mutant mice have the same spinally mediated behavioral abnormalities, increased sensitivity to noxious heat and a profound loss in mechanical ...
Basbaum, Allan I, Cilluffo, Marianne, Kim, Ashley S, Phelps, Patricia E, Wang, Xidao, Yvone, Griselda M   +5 more
core  

Tetrodotoxin-resistant Na⁺currents and inflammatory hyperalgesia [PDF]

, 1999
Michael S. Gold
openalex   +1 more source

Interactions between brain and spinal cord mediate value effects in nocebo hyperalgesia

Science, 2017
Alexandra Tinnermann, S. Geuter, S. Geuter, C. Sprenger, C. Sprenger, J. Finsterbusch, C. Büchel   +6 more
semanticscholar   +1 more source

Questioning the pros and cons of metformin treatment in diabetic peripheral neuropathy

Journal of Diabetes Investigation, EarlyView.
Hiroki Mizukami
wiley   +1 more source

Endocannabinoid signaling in stress, nausea, and vomiting

Neurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
Abstract Background Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and ...
Marieka V. DeVuono, Thangam Venkatesan, Cecilia J. Hillard   +2 more
wiley   +1 more source

Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan‐induced thermal hyperalgesia [PDF]

, 1999
Michael G Osborne, Terence J. Coderre
openalex   +1 more source

Could the Therapeutic Effect of Physical Activity on Irritable Bowel Syndrome Be Mediated Through Changes to the Gut Microbiome? A Narrative and Hypothesis Generating Review

Neurogastroenterology &Motility, Volume 37, Issue 6, June 2025.
Schematic illustrating the effects of physical activity in healthy controls and IBS patients. ABSTRACT Background Irritable bowel syndrome (IBS) is one of the most prevalent gastrointestinal (GI) disorders worldwide. Defined as a disorder of gut‐brain interaction, its pathophysiology is still not completely clear.
Hannah B. Lindsell, Neil C. Williams, Daniele Magistro, Maura Corsetti, Gemma E. Walton, Kirsty A. Hunter   +5 more
wiley   +1 more source