Results 171 to 180 of about 84,168 (327)

Analgesic effect of chronic oral administration of aerial part of Marrubium Vulgare in diabetic rats

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
BACKGROUND AND OBJECTIVE: Considering the antidiabetic and anti-inflammatory effect of marrubium vulgare (MV), this study was designed to investigate the analgesic effect of MV on formalin-induced nociceptive response (standard formalin test) in diabetic
M Roghani,, T Balouch Nejad Mojarad
doaj  

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

open access: yesChemMedChem, Volume 20, Issue 20, October 15, 2025.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti   +4 more
wiley   +1 more source

The effect of AqueousExtractofElaeagnusangustifolia on Diabetic Neuropathic Pain in Streptozotocin-induced Diabetic Rats

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives:One of the common complications of diabetes is nervous system disorder and diabetic neuropathy. In various studies, it has been reported that flavonoid and polyphenolic compounds of plants improve diabetic neuropathy. Due to the
Omid Reza Tamtaji   +2 more
doaj  

Suppression of Hyperalgesia in Streptozotocin-Induced Diabetic Mice by a Lipopolysaccharide from Pantoea agglomerans.

open access: bronze, 1994
Junzo Kamei   +7 more
openalex   +2 more sources

Intestinal inflammation induces glymphatic remodeling, priming early neurodegenerative signals in male mice

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Inflammatory bowel disease triggers extraintestinal manifestations, including in the central nervous system (CNS). However, the direct impact of peripheral inflammation on the CNS is largely unknown. METHODS Using a mouse model of colitis with pain and anxiety‐like behavior, we investigated the intricate pathogenic link between ...
Clara Ciampi   +20 more
wiley   +1 more source

Tuina Alleviates Anxiety‐Like Behaviors Associated With Neuropathic Pain Through the Modulation of Synaptic Plasticity in the Anterior Cingulate Cortex

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
Tuina alleviates CCI‐induced neuropathic pain and anxiety‐like behaviors, and counteracts the enhancement of excitatory synaptic transmission and abnormal synaptic plasticity, potentially by modulating GluN2B/PSD‐95/CaMKII/GluR1 signaling. ABSTRACT Background As the disease progresses, neuropathic pain (NP) is often accompanied by anxiety‐like ...
Rentuya Na   +6 more
wiley   +1 more source

Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objectives This systematic review aims to offer indications on how drug administration affects postoperative pain in patients undergoing orthognathic surgery. Material and Methods We searched Pubmed, Scopus, and Web of Science for articles pertaining to our research topic.
Gianna Dipalma   +11 more
wiley   +1 more source

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