Results 1 to 10 of about 47,507 (194)
Hyperinsulinemia Associated Depression
Clinical Medicine Insights: Endocrinology and Diabetes, 2022 Hyperinsulinemia promotes fat accumulation, causing obesity. Being an inflammatory state, obesity can induce further inflammation and is a risk factor for HPA (hypothalamic pituitary axis) dysregulation through hypercortisolism-related hyperglycemia.
Haider Sarwar +12 more
doaj +3 more sources
Valproate-Related Hyperinsulinemia
Pediatric Neurology Briefs, 2006 Changes in insulin metabolism during treatment with valproate (VPA) were investigated in a study of 51 patients receiving monotherapy (31 male and 20 female) and 45 healthy controls at University of Oulu, and Hospital of Children and Adolescents ...
J Gordon Millichap
doaj +4 more sources
Hyperinsulinemia, Insulin Resistance, and Hypertension
Journal of Cardiovascular Pharmacology, 1994 Obesity is the most common reason for insulin resistance with consequent hyperinsulinemia. Other reasons for hyperinsulinemia are type II diabetes mellitus and a genetic predisposition with a family history of hypertension. Hyperinsulinemia is considered to cause blood pressure elevation and is generally accepted as an independent risk factor for ...
Gerd Bönner
openalex +4 more sources
In Vitro Chronic Hyperinsulinemia Induces Remodelling of Vascular Smooth Muscle Cells from Young Men and Women in a Sex Hormone Independent Manner [PDF]
PathophysiologyElevated circulating insulin levels between 80 and 100 µU/mL characterize hyperinsulinemia, which often leads to metabolic disorders such as obesity, insulin resistance, and type 2 diabetes (T2D).
Ashley Jazzar +3 more
doaj +2 more sources
Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration [PDF]
BiomedicinesMetabolic peptides can influence metabolic processes and contribute to both inflammatory and/or anti-inflammatory responses. Studies have shown that there are thousands of metabolic peptides, made up of short chains of amino acids, that the human body ...
Camille Green +4 more
doaj +2 more sources
Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats [PDF]
CellsRotenone, a naturally occurring compound derived from the roots of tropical plants, is used as a broad-spectrum insecticide, piscicide, and pesticide.
Vandana Zaman +3 more
doaj +2 more sources
Use of the SGLT2 inhibitor canagliflozin for control of refractory equine hyperinsulinemia and laminitis [PDF]
Open Veterinary Journal, 2022 Background: Hyperinsulinemia associated with pituitary pars intermedia dysfunction (PPID) and/or equine metabolic syndrome (EMS) is well documented to put horses at high risk of laminitis.
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Hyperinsulinemia in Obesity, Inflammation, and Cancer [PDF]
Diabetes & Metabolism Journal, 2021 The relative insufficiency of insulin secretion and/or insulin action causes diabetes. However, obesity and type 2 diabetes mellitus can be associated with an absolute increase in circulating insulin, a state known as hyperinsulinemia. Studies are beginning to elucidate the cause-effect relationships between hyperinsulinemia and numerous consequences ...
Anni M.Y. Zhang +3 more
openaire +6 more sources
Frontiers in Clinical Diabetes and Healthcare, 2023 ObjectiveThis study aimed to investigate the clinical implications of fasting serum insulin (FINS) levels in subjects with type 2 diabetes who were receiving insulin therapy.MethodsA total of 1,553 subjects with type 2 diabetes [774 subjects who had ...
Lingli Zhou +8 more
doaj +1 more source
Acute effects of euglycemic‐hyperinsulinemia on myocardial contractility in male mice
Physiological Reports, 2022 Type 2 diabetes and obesity are associated with increased risk of cardiovascular disease, including heart failure. A hallmark of these dysmetabolic states is hyperinsulinemia and decreased cardiac reserve.
Satya Murthy Tadinada +4 more
doaj +1 more source