Results 91 to 100 of about 105,064 (356)

Effects of the Sodium-Glucose Cotransporter-2 Inhibitor Velagliflozin on Insulin Concentrations in Horses With Insulin Dysregulation. [PDF]

J Vet Intern Med
ABSTRACT Background Sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are promising treatments to manage hyperinsulinemia in horses with insulin dysregulation (ID). Hypothesis The SGLT2i velagliflozin decreases insulin concentration in horses with ID. Animals Privately‐owned adult horses (n = 37) with laboratory‐confirmed ID (low‐dose oral sugar test ...
Thane K, Voth R, Klee R, Warnken T, Chukwu V, Frank N.   +5 more
europepmc   +2 more sources

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source

Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders

Nature Communications, 2018
Hyperinsulinemia is the earliest symptom of insulin resistance (IR), but a causal relationship between the two remains to be established. Here we show that a protein kinase D2 (PRKD2) nonsense mutation (K410X) in two rhesus monkeys with extreme ...
Yao Xiao, Can Wang, Jia-Yu Chen, Fujian Lu, Jue Wang, N. Hou, Xiaomin Hu, Fanxin Zeng, Dongwei Ma, Xueting Sun, Yi Ding, Yan Zhang, Wen Zheng, Yuli Liu, Haibao Shang, Wenzhen Zhu, C. Han, Yulin Zhang, K. Ouyang, Liangyi Chen, Ju Chen, R. Xiao, Chuan-Yun Li, Xiuqin Zhang   +23 more
semanticscholar   +1 more source

Risk Assessment and Determination of Factors That Cause the Development of Hyperinsulinemia in School-Age Adolescents

Medicina, 2021
Background and Objectives: Hyperinsulinemia and insulin resistance are not synonymous; if the risk of developing insulin resistance in adolescents is monitored, they do not necessarily have hyperinsulinemia.
Igor Lukic, Nikola Savic, Maja Simic, Nevena Rankovic, Dragica Rankovic, Ljubomir Lazic   +5 more
doaj   +1 more source

Circulating vaspin is unrelated to insulin sensitivity in a cohort of nondiabetic humans [PDF]

, 2010
Objective: To study the association of vaspin with glucose metabolism. Design: Cross-sectional and intervention study. Subjects and methods: The association of serum vaspin with metabolic and anthropometric characteristics was investigated in 108
Arafat, Ayman, M., Isken, Frank, Loeffelholz, Christian von, Mai, Knut, Möhlig, Matthias, Pfeiffer, Andreas F. H., Randeva, Harpal S., Spranger, Joachim, Weickert, Martin O.   +8 more
core   +1 more source

Thirteen simple lifestyle scores and risk of cancer, cardiovascular disease, diabetes, and mortality: Prospective cohort study in the UK Biobank

International Journal of Cancer, EarlyView.
What's New? Cancer, cardiovascular disease, and type 2 diabetes share common lifestyle‐related risk factors. This large‐scale prospective cohort study examined and compared the associations between 13 simple lifestyle scores and these major non‐communicable diseases.
Jie Ding, Ben Schöttker, Hermann Brenner, Michael Hoffmeister   +3 more
wiley   +1 more source

Does Oxidative Stress Cause Insulin Resistance in Women with Polycystic Ovary Syndrome?

مجله دانشکده پزشکی اصفهان, 2020
Background: Polycystic ovary syndrome (PCOS), with a prevalence of 4-12 percent, is the most common endocrine-metabolic disorder in reproductive age of women.
Farideh Zafari-Zangeneh
doaj   +1 more source

Intersection between metabolic dysfunction, high fat diet consumption, and brain aging [PDF]

, 2010
Deleterious neurochemical, structural, and behavioral alterations are a seemingly unavoidable aspect of brain aging. However, the basis for these alterations, as well as the basis for the tremendous variability in regards to the degree to which these ...
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core   +1 more source

Circulating fatty acid binding protein 4 (FABP‐4) concentrations and mortality in individuals with colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

International Journal of Cancer, EarlyView.
What's New? Higher pre‐diagnostic body mass index has been associated with higher risk of mortality in individuals with colorectal cancer; however, the mechanism remains unclear. This prospective analysis of incident colorectal cancer cases within the European Prospective Investigation into Cancer and Nutrition cohort study addressed potential collider
Thu Thi Pham, Katharina Nimptsch, Krasimira Aleksandrova, Mazda Jenab, Veronika Fedirko, Anja Olsen, Anne Tjønneland, Claire Cadeau, Gianluca Severi, Matthias B. Schulze, Renée Turzanski Fortner, Verena Katzke, Claudia Agnoli, Carlotta Sacerdote, Rosario Tumino, Simona Signoriello, Camino Trobajo‐Sanmartín, Jesús‐Humberto Gómez, María‐Dolores Chirlaque, Maria‐Jose Sánchez, Marta Crous‐Bou, Anne May, Alicia Heath, Dagfinn Aune, Elisabete Weiderpass, Tobias Pischon   +25 more
wiley   +1 more source

Influence of insulin resistance on renal function in patients with abdominal obesity.

Medičnì Perspektivi, 2015
The purpose of the study - to assess the role of insulin resistance in the development of initial manifestations of renal disease in patients with abdominal obesity.
T. O. Pertseva, M. K. Rokutova
doaj   +1 more source