Results 101 to 110 of about 103,854 (365)

Changes in insulin and insulin signaling in Alzheimer\u27s disease: Cause or consequence? [PDF]

, 2016
Individuals with type 2 diabetes have an increased risk for developing Alzheimer’s disease (AD), although the causal relationship remains poorly understood. Alterations in insulin signaling (IS) are reported in the AD brain.
Holtzman, David M, Macauley, Shannon L, Stanley, Molly   +2 more
core   +2 more sources

Thirteen simple lifestyle scores and risk of cancer, cardiovascular disease, diabetes, and mortality: Prospective cohort study in the UK Biobank

International Journal of Cancer, EarlyView.
What's New? Cancer, cardiovascular disease, and type 2 diabetes share common lifestyle‐related risk factors. This large‐scale prospective cohort study examined and compared the associations between 13 simple lifestyle scores and these major non‐communicable diseases.
Jie Ding, Ben Schöttker, Hermann Brenner, Michael Hoffmeister   +3 more
wiley   +1 more source

Insulin resistance and reduced brain glucose metabolism in the aetiology of Alzheimer’s disease

Journal of Metabolic Health, 2016
Significant epidemiological and clinical evidence has emerged that suggests Alzheimer’s disease (AD) can be added to the list of chronic illnesses that are primarily caused by modern diets and lifestyles at odds with human physiology.
Amy L. Berger
doaj   +1 more source

Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]

, 2011
ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda, Beiser, Alexa S, Debette, Stephanie, Decarli, Charles, Fox, Caroline S, Himali, Jayandra J, Seshadri, Sudha, Tan, Zaldy S, Vasan, Ramachandran S, Wolf, Philip A   +9 more
core   +2 more sources

Mice endometrium receptivity in early pregnancy is impaired by maternal hyperinsulinemia

Molecular Medicine Reports, 2017
Previous studies have investigated the lower embryo implantation rates in women with polycystic ovary syndrome, obesity and type 2 diabetes, and specifically the association between the abnormal oocyte and embryo and hyperinsulinemia.
Runqin Li, Juan Wu, Junlin He, Yingxiong Wang, Xue-qing Liu, Xuemei Chen, Chao Tong, Yubin Ding, Yan Su, Wenqi Chen, Chen Zhang, Rufei Gao   +11 more
semanticscholar   +1 more source

Circulating fatty acid binding protein 4 (FABP‐4) concentrations and mortality in individuals with colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

International Journal of Cancer, EarlyView.
What's New? Higher pre‐diagnostic body mass index has been associated with higher risk of mortality in individuals with colorectal cancer; however, the mechanism remains unclear. This prospective analysis of incident colorectal cancer cases within the European Prospective Investigation into Cancer and Nutrition cohort study addressed potential collider
Thu Thi Pham, Katharina Nimptsch, Krasimira Aleksandrova, Mazda Jenab, Veronika Fedirko, Anja Olsen, Anne Tjønneland, Claire Cadeau, Gianluca Severi, Matthias B. Schulze, Renée Turzanski Fortner, Verena Katzke, Claudia Agnoli, Carlotta Sacerdote, Rosario Tumino, Simona Signoriello, Camino Trobajo‐Sanmartín, Jesús‐Humberto Gómez, María‐Dolores Chirlaque, Maria‐Jose Sánchez, Marta Crous‐Bou, Anne May, Alicia Heath, Dagfinn Aune, Elisabete Weiderpass, Tobias Pischon   +25 more
wiley   +1 more source

Metabolic syndrome, hyperinsulinemia, and cancer [PDF]

The American Journal of Clinical Nutrition, 2007
The term metabolic syndrome describes the association between obesity, insulin resistance, and the risk of several prominent chronic diseases, including cancer. The causal link between many of these components remains unexplained, however. What is clear are the events that precede the development of the syndrome itself.
Morvarid Kabir, Richard N. Bergman, Stella P. Kim, Isabel R. Hsu   +3 more
openaire   +3 more sources

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Current treatment options for acanthosis nigricans

Clinical, Cosmetic and Investigational Dermatology, 2018
Nupur U Patel,1 Catherine Roach,1 Hossein Alinia,1 William W Huang,1 Steven R Feldman1–3 1Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, 2Department of Pathology, Wake ...
Patel NU, Roach C, Alinia H, Huang WW, Feldman SR   +4 more
doaj  

The effect of the glycemic index of an evening meal on the metabolic responses to a standard high glycemic index breakfast and subsequent exercise in men [PDF]

, 2005
The study investigated the effect of the glycemic index of an evening meal on responses to a standard high glycemic index (HGI) breakfast the following morning. The metabolic responses to exercise 3 hours after breakfast were also investigated.
Nute, Maria, Stevenson, Emma, Swaile, Peter, Tsui, Monica, Williams, Clyde   +4 more
core   +1 more source