Results 141 to 150 of about 103,854 (365)

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak, Karolina Kowalcze, Marek Krzystanek, Witold Szkróbka, Bogusław Okopień   +4 more
wiley   +1 more source

Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia. [PDF]

, 1988
Boris Draznin, Karl E. Sussman, Robert H. Eckel, M Kao, Trudy J. Yost, Nancy A. Sherman   +5 more
openalex   +1 more source

Incidence of Autoimmune Diseases in 30,340 Danish Women With Polycystic Ovary Syndrome (PCOS) Compared to 151,520 Controls. A National Cohort Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Autoimmunity can be part of the pathogenesis of polycystic ovary syndrome (PCOS), but prospective studies on autoimmune disease in population based cohorts are lacking. This study aimed to investigate incidence rates of autoimmune disease in Danish women with PCOS before and after PCOS diagnosis compared to controls.
Dorte Glintborg, Jens‐Jakob Kjer Møller, Katrine Hass Rubin, Louise Lehmann Christensen, Marianne Skovsager Andersen   +4 more
wiley   +1 more source

The effect of a multidisciplinary weight loss program on renal circadian rhythm in obese adolescents

, 2019
Adolescent obesity is a serious health problem associated with many comorbidities. Obesity-related alterations in circadian rhythm have been described for nocturnal blood pressure and for metabolic functions.
Bruneel, Elke, De Guchtenaere, Ann, Dejonckheere, Sarah, Everaert, Karel, Keersmaekers, Laura, Pauwaert, Kim, Roggeman, Saskia, Van der Jeugt, Jolien, Vande Walle, Johan   +8 more
core   +1 more source

Role of Dietary Factors in the Hyperinsulinemia of Genetically Obese Hyperglycemic (ob/ob) Mice [PDF]

, 1982
Peter R. Flatt, Clifford J. Bailey
openalex   +1 more source

Combined liraglutide and metformin therapy in overweight or obese women with polycystic ovary syndrome: A systematic review and meta‐analysis

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Purpose Overweight or obese women with polycystic ovary syndrome (PCOS) often experience significant metabolic and hormonal disturbances. This systematic review and meta‐analysis evaluated whether liraglutide combined with metformin is more effective than metformin alone in improving glycaemic control, lipid metabolism, body mass index (BMI ...
Jing Ling, Tiantian Wang, Wenrui Huang, Yuhua Zhen, Mingzi Zhang, Xingzi Fang, Wencong Song, Xuelian Du   +7 more
wiley   +1 more source

Potentsial'nye vozmozhnosti metformina v profilaktike i lechenii onkologicheskikh zabolevaniy u bol'nykh sakharnym diabetom 2 tipa

Ожирение и метаболизм, 2011
Diabetes mellitus is associated with increased risk of several types of cancer, and also with increased cancer mortality. Chronic hyperinsulinemia plays the main pathogenetic role in this association, which is mediated by a number of molecular mechanisms,

doaj   +1 more source

Accelerated Growth and Abnormal Glucose Tolerance in Young Female Rats Exposed to Fetal Hyperinsulinemia [PDF]

, 1987
M Chung-Ja, Nancy L Gelardi, William Oh
openalex   +1 more source

Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited.

Canadian Journal of Cardiology, 2020
A. D. da Silva, Jussara M. do Carmo, Xuan Li, Zhen Wang, A. Mouton, J. Hall   +5 more
semanticscholar   +1 more source

Insulin facilitates entry of calcium ions into human and murine erythrocytes via Piezo1: a newly identified mechanism with implications for type 2 diabetes

The FEBS Journal, EarlyView.
Despite being enucleated, mammalian red blood cells (RBCs) possess complex signaling mechanisms. Here, we show that insulin signals through the mechanosensitive channel Piezo1 to promote influx of calcium ions. This newly identified pathway is disrupted in a murine model of type 2 diabetes and may contribute to driving circulatory deficits in prevalent
Lennart Kuck, Tia A. Griffith, Antony P. McNamee, Jason N. Peart, John H. Wilson, Ajay Sharma, Lavanya A. Sharma, Kai Robertson, Eugene F. Du Toit, Michael J. Simmonds   +9 more
wiley   +1 more source