Results 141 to 150 of about 86,017 (262)

Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
Risk factors for GDM contribute to a hyperglycemic intrauterine environment, which may in turn impair ANS function in the offspring. Altered ANS activity can be assessed through measures such as HRV. ABSTRACT Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications, arising from inadequate insulin secretion and increased ...
Virginia Beretta   +7 more
wiley   +1 more source

Diabetes Mellitus and Reprogrammed Glucose Metabolism in Pancreatic Cancer: Features for Clinical Translation [PDF]

open access: yes, 2016
The reprogrammed metabolism of cancer cells underlies the shift of glucose energetics from the highly efficient oxidative phosphorylation to the less efficient aerobic glycolysis, the Warburg effect.
BASSO, DANIELA   +4 more
core  

Potential Hypoglycemic, Hypolipidemic, and Hypouricemic Bioactive Components From Ampelopsis grossedentata Explored by Affinity Ultrafiltration With Three Enzyme Targets

open access: yeseFood, Volume 7, Issue 2, April 2026.
By integrating bioaffinity ultrafiltration coupled with HPLC‐MS/MS, this study identified quercetin, myricetrin, dihydromyricetin, and taxifolin from Ampelopsis grossedentata as key inhibitors of α‐glucosidase, pancreatic lipase, and xanthine oxidase, highlighting the promising potential of A.
Siyang Mao   +5 more
wiley   +1 more source

Real‐World Weight Loss Is Associated With a Reduction in Cancer Risk

open access: yesObesity, Volume 34, Issue 4, Page 928-938, April 2026.
ABSTRACT Objective Obesity is a major risk factor for multiple cancers, yet the impact of nonsurgical weight loss on cancer risk remains uncertain. Our objective was to evaluate whether real‐world nonsurgical weight loss is associated with a reduced risk of developing cancer.
Kenda Alkwatli   +7 more
wiley   +1 more source

Dual action of imeglimin on insulin secretion and sensitivity in type 2 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2744-2756, April 2026.
Abstract Aims Imeglimin is a novel oral hypoglycemic agent approved for the treatment of type 2 diabetes in Japan, with dual actions to enhance insulin secretion and improve insulin sensitivity, suggested by preclinical evidence. However, the effect of imeglimin on tissue‐specific insulin sensitivity and glucose kinetics using glucose tracers is ...
Tsubasa Tajima   +10 more
wiley   +1 more source

Safety, feasibility, and dose‐dependent metabolic effects of endoscopic duodenal pulsed electric field therapy in adults with type 2 diabetes: Results from two multicentre proof‐of‐concept studies

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3367-3376, April 2026.
Abstract Aims The duodenum plays a central role in metabolic regulation, influencing insulin sensitivity, and glucose homeostasis. In type 2 diabetes (T2D), structural and functional abnormalities of the duodenal mucosa (“diabetic duodenopathy”) are increasingly recognized as contributors to insulin resistance and dysglycaemia.
David N. O'Neal   +12 more
wiley   +1 more source

Metabolic Complications and Ultrasound‐Detected Liver Abnormalities in Paediatric Patients With Duchenne Muscular Dystrophy

open access: yesPediatric Obesity, Volume 21, Issue 4, April 2026.
ABSTRACT Background Nutritional care in Duchenne muscular dystrophy (DMD), a progressive neuromuscular disorder, is particularly important due to the high risk of obesity in childhood and malnutrition in adolescence. Objectives The study aimed to evaluate metabolic complications in DMD, such as liver USS (ultrasound scan) abnormalities and abnormal ...
Karolina Śledzińska   +14 more
wiley   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, Volume 248, Issue 4, Page 675-688, April 2026.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

open access: yesObesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

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