Results 141 to 150 of about 86,017 (262)
Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance
Risk factors for GDM contribute to a hyperglycemic intrauterine environment, which may in turn impair ANS function in the offspring. Altered ANS activity can be assessed through measures such as HRV. ABSTRACT Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications, arising from inadequate insulin secretion and increased ...
Virginia Beretta +7 more
wiley +1 more source
Diabetes Mellitus and Reprogrammed Glucose Metabolism in Pancreatic Cancer: Features for Clinical Translation [PDF]
The reprogrammed metabolism of cancer cells underlies the shift of glucose energetics from the highly efficient oxidative phosphorylation to the less efficient aerobic glycolysis, the Warburg effect.
BASSO, DANIELA +4 more
core
By integrating bioaffinity ultrafiltration coupled with HPLC‐MS/MS, this study identified quercetin, myricetrin, dihydromyricetin, and taxifolin from Ampelopsis grossedentata as key inhibitors of α‐glucosidase, pancreatic lipase, and xanthine oxidase, highlighting the promising potential of A.
Siyang Mao +5 more
wiley +1 more source
Real‐World Weight Loss Is Associated With a Reduction in Cancer Risk
ABSTRACT Objective Obesity is a major risk factor for multiple cancers, yet the impact of nonsurgical weight loss on cancer risk remains uncertain. Our objective was to evaluate whether real‐world nonsurgical weight loss is associated with a reduced risk of developing cancer.
Kenda Alkwatli +7 more
wiley +1 more source
Dual action of imeglimin on insulin secretion and sensitivity in type 2 diabetes
Abstract Aims Imeglimin is a novel oral hypoglycemic agent approved for the treatment of type 2 diabetes in Japan, with dual actions to enhance insulin secretion and improve insulin sensitivity, suggested by preclinical evidence. However, the effect of imeglimin on tissue‐specific insulin sensitivity and glucose kinetics using glucose tracers is ...
Tsubasa Tajima +10 more
wiley +1 more source
Abstract Aims The duodenum plays a central role in metabolic regulation, influencing insulin sensitivity, and glucose homeostasis. In type 2 diabetes (T2D), structural and functional abnormalities of the duodenal mucosa (“diabetic duodenopathy”) are increasingly recognized as contributors to insulin resistance and dysglycaemia.
David N. O'Neal +12 more
wiley +1 more source
ABSTRACT Background Nutritional care in Duchenne muscular dystrophy (DMD), a progressive neuromuscular disorder, is particularly important due to the high risk of obesity in childhood and malnutrition in adolescence. Objectives The study aimed to evaluate metabolic complications in DMD, such as liver USS (ultrasound scan) abnormalities and abnormal ...
Karolina Śledzińska +14 more
wiley +1 more source
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann +8 more
wiley +1 more source
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley +1 more source

