Results 11 to 20 of about 105,064 (356)
Hyperinsulinemia Associated Depression
Clinical Medicine Insights: Endocrinology and Diabetes, 2022 Hyperinsulinemia promotes fat accumulation, causing obesity. Being an inflammatory state, obesity can induce further inflammation and is a risk factor for HPA (hypothalamic pituitary axis) dysregulation through hypercortisolism-related hyperglycemia.
Haider Sarwar +12 more
doaj +3 more sources
DPP4 Activity, Hyperinsulinemia and Atherosclerosis.
The Journal of Clinical Endocrinology & Metabolism, 2021 CONTEXT Obesity and type 2 diabetes are associated with chronic hyperinsulinemia, elevated plasma levels of dipeptidyl peptidase-4 (DPP4), and a pro-atherosclerotic milieu.
Kaitlin M Love, Zhenqi Liu
semanticscholar +4 more sources
Valproate-Related Hyperinsulinemia
Pediatric Neurology Briefs, 2006 Changes in insulin metabolism during treatment with valproate (VPA) were investigated in a study of 51 patients receiving monotherapy (31 male and 20 female) and 45 healthy controls at University of Oulu, and Hospital of Children and Adolescents ...
J Gordon Millichap
doaj +4 more sources
Hyperinsulinemia: a Cause of Obesity? [PDF]
Current Obesity Reports, 2017 Purpose of ReviewThis perspective is motivated by the need to question dogma that does not work: that the problem is insulin resistance (IR). We highlight the need to investigate potential environmental obesogens and toxins.Recent FindingsThe prequel to ...
K. Erion, B. Corkey
semanticscholar +4 more sources
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. [PDF]
Journal of Clinical Investigation, 1991 Erling A. Anderson +4 more
openalex +2 more sources
Hyperinsulinemia, Insulin Resistance, and Hypertension
Journal of Cardiovascular Pharmacology, 1994 Obesity is the most common reason for insulin resistance with consequent hyperinsulinemia. Other reasons for hyperinsulinemia are type II diabetes mellitus and a genetic predisposition with a family history of hypertension. Hyperinsulinemia is considered to cause blood pressure elevation and is generally accepted as an independent risk factor for ...
Gerd Bönner
openalex +4 more sources
Journal of Clinical Medicine, 2022 Metabolic derangement with poor glycemic control accompanying overweight and obesity is associated with chronic low-grade inflammation and hyperinsulinemia.
G. Püschel, J. Klauder, J. Henkel
semanticscholar +1 more source
Frontiers in Clinical Diabetes and Healthcare, 2023 ObjectiveThis study aimed to investigate the clinical implications of fasting serum insulin (FINS) levels in subjects with type 2 diabetes who were receiving insulin therapy.MethodsA total of 1,553 subjects with type 2 diabetes [774 subjects who had ...
Lingli Zhou +8 more
doaj +1 more source
Chronic hyperinsulinemia promotes human hepatocyte senescence
Molecular Metabolism, 2022 Objective: Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells have been identified in multiple tissues in different metabolic and other aging ...
Ritesh K. Baboota +10 more
doaj +1 more source
Diabetes, 2021 Aging, obesity, and diabetes are major risk factors for the severe progression and outcome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019 [COVID-19]), but the underlying mechanism is not yet fully ...
Jihoon Shin +6 more
semanticscholar +1 more source