Results 11 to 20 of about 89,537 (288)

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

open access: yesHepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk   +6 more
wiley   +1 more source

A case of acanthosis nigricans in a HIV-infected patient [PDF]

open access: yes, 2020
Background: To date, very little information is available concerning the relationship between acanthosis nigricans (AN) and infection with human immunodeficiency virus type 1 (HIV-1).
De Vincentiis, Ludovica   +5 more
core   +1 more source

Valproate-Related Hyperinsulinemia

open access: yesPediatric Neurology Briefs, 2006
Changes in insulin metabolism during treatment with valproate (VPA) were investigated in a study of 51 patients receiving monotherapy (31 male and 20 female) and 45 healthy controls at University of Oulu, and Hospital of Children and Adolescents ...
J Gordon Millichap
doaj   +1 more source

The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice [PDF]

open access: yes, 2016
Hyperinsulinemia is a risk factor for late-onset Alzheimer's disease (AD). In vitro experiments describe potential connections between insulin, insulin signaling, and amyloid-β (Aβ), but in vivo experiments are needed to validate these relationships ...
Caesar, Emily E   +9 more
core   +2 more sources

Hypertriglyceridemia in equines with refractory hyperinsulinemia treated with SGLT2 inhibitors

open access: yesOpen Veterinary Journal, 2023
Background: Sodium-Glucose CoTransporter-2 [SGLT2] inhibitors, the -flozin group of drugs, which block glucose reuptake in the renal proximal tubule, are being increasingly used off-label to treat horses with refractory hyperinsulinemia. After two years
Eleanor M. Kellon, Kathleen M. Gustafson
doaj   +1 more source

Examining the role of insulin in the regulation of cardiovascular health [PDF]

open access: yes, 2013
A substantial body of evidence has reported that insulin has direct actions on the cardiovascular system independent of its systemic effects on plasma glucose or lipids.
Salt, Ian P.
core   +1 more source

The rs12617336 and rs17574 Dipeptidyl Peptidase-4 Polymorphisms Are Associated With Hypoalphalipoproteinemia and Dipeptidyl Peptidase-4 Serum Levels: A Case-Control Study of the Genetics of Atherosclerotic Disease (GEA) Cohort

open access: yesFrontiers in Genetics, 2021
Dipeptidyl peptidase-4 (DPP4) can influence lipid homeostasis and atherosclerosis progression. We aimed to assess the association of DPP4 gene polymorphisms with hypoalphalipoproteinemia and DPP4 serum levels, in a cohort of Mexican individuals.
Gilberto Vargas-Alarcón   +9 more
doaj   +1 more source

The contribution of hyperinsulinemia to the hyperandrogenism of polycystic ovary syndrome

open access: yesJournal of Metabolic Health, 2019
Background: Polycystic Ovary Syndrome (PCOS) is a very common endocrine disorder of young women. Aim: The proper treatment of PCOS requires a thorough understanding of the underlying cause of disease.
Nadia B. Pateguana, Alvin Janes
doaj   +1 more source

Overview and New Insights into the Metabolic Syndrome: Risk Factors and Emerging Variables in the Development of Type 2 Diabetes and Cerebrocardiovascular Disease

open access: yesMedicina, 2023
Metabolic syndrome (MetS) is considered a metabolic disorder that has been steadily increasing globally and seems to parallel the increasing prevalence of obesity.
Melvin R. Hayden
doaj   +1 more source

Central Obesity and BMI Associated with Different Phenotypes of Polycystic Ovary Syndrome in Adolescent [PDF]

open access: yes, 2017
Adipose tissue distribution is effective in metabolic complications resulting from obesity. Fat accumulation in the body, particularly increase in visceral fat, is a major risk factor of diabetes and cardiovascular diseases.
Akbaezadeh, M. (Marzieh)   +1 more
core   +3 more sources

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