Results 31 to 40 of about 89,537 (288)
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]
, 2011 ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda +9 more
core +2 more sources
Adipocyte, 2020 Hyperinsulinemia is the hallmark of the development of insulin resistance and precedes the diagnosis of type 2 diabetes. Here we evaluated the effects of prolonged exposure (≥4 days) to high insulin doses (150 nM) in vitro in two adipose cell types ...
A. Rossi +7 more
doaj +1 more source
Cells, 2022 The dysregulation of microRNAs has recently been associated with cancer development and progression in pancreatic ductal adenocarcinoma (PDAC) and cystic pancreatic lesions.
Christian Prinz +2 more
doaj +1 more source
Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study. [PDF]
, 2013 ObjectiveWe aimed to identify factors that are independently associated with the metabolic clearance rate of insulin (MCRI) and to examine the association of MCRI with incident type 2 diabetes in nondiabetic Hispanics and African Americans.Research ...
Anderson, Andrea M +10 more
core +2 more sources
Does Oxidative Stress Cause Insulin Resistance in Women with Polycystic Ovary Syndrome?
مجله دانشکده پزشکی اصفهان, 2020 Background: Polycystic ovary syndrome (PCOS), with a prevalence of 4-12 percent, is the most common endocrine-metabolic disorder in reproductive age of women.
Farideh Zafari-Zangeneh
doaj +1 more source
Biomedicines, 2021 Acute porphyria attacks are associated with the strong up-regulation of hepatic heme synthesis and over-production of neurotoxic heme precursors. First-line therapy is based on carbohydrate loading.
Isabel Solares +11 more
doaj +1 more source
International Journal of Pharmacy Practice, EarlyView., 2020 Abstract Objectives Evidence‐based guidelines have the potential to reduce variation and increase prescribing quality. Identifying the key determinants to their uptake, using a theory‐based approach, may assist in the design of successful interventions to increase their adoption into practice.
Paulina Paksaite +4 more
wiley +1 more source
Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
Periodontology 2000, EarlyView., 2023 Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti +2 more
wiley +1 more source
Role of lipotoxicity in achieving glycemic control in patients with diabetes type 2 and obesity
Медицинский совет, 2013 Obesity increases the risk of diabetes mellitus type 2 due to the development of insulin resistance. Therapy for diabetes mellitus type 2 is limited by a relatively small amount of knowledge on the mechanisms of insulin resistance, despite the ...
А. S. Ametov +4 more
doaj +1 more source
The effect of the glycemic index of an evening meal on the metabolic responses to a standard high glycemic index breakfast and subsequent exercise in men [PDF]
, 2005 The study investigated the effect of the glycemic index of an evening meal on responses to a standard high glycemic index (HGI) breakfast the following morning. The metabolic responses to exercise 3 hours after breakfast were also investigated.
Nute, Maria +4 more
core +1 more source