Results 31 to 40 of about 47,507 (194)
Hyperinsulinemia and oxidative stress
Physiological Research, 2002 The aim of the study was to compare the effect of short-term hyperglycemia and short-term hyperinsulinemia on parameters of oxidative stress in Wistar rats. Twenty male rats (aged 3 months, average body weight 325 g) were tested by hyperinsulinemic clamp (100 IU/l) at two different glycemia levels (6 and 12 mmol/l).
P, Kyselová +4 more
openaire +2 more sources
Pediatric Reports, 2022 Background: Hyperinsulinemic hypoglycemia (HH) is an important cause of persistent hypoglycemia in newborns and infants. Recently, PMM2 (phosphomannomutase 2) mutation has been associated with HH, especially in conjunction with polycystic kidney disease (
Ratna Acharya, Kiran Upadhyay
doaj +1 more source
21 hypoglycemia cases with hyperinsulinemia [PDF]
International Journal of Pediatric Endocrinology, 2013 Congenital hyperinsulinemic hypoglycemia (CHI) is the common cause of severe hypoglycemia in infancy. Profound hypoglycemia requires appropriate diagnosis and aggressive treatment to prevent severe and irreversible brain damage. Here we report 21 Japanese hypoglycemia cases with severe hyperinsulinemia.
Akiko Yamamoto +5 more
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Children, 2023 Obesity is a multifactorial disease whose onset and development are shaped by the individual genetic background. The melanocortin 4 receptor gene (MC4R) is involved in the regulation of food intake and energy expenditure.
Joaquín Carrasco-Luna +7 more
doaj +1 more source
Regulation of Insulin Clearance by Non-Esterified Fatty Acids
Biomedicines, 2022 Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar +8 more
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Insects, 2018 Mosquitoes have distinct developmental and adult life history, and the vectorial capacity of females has been shown to be affected by the larval nutritional environment.
Rana Pooraiiouby +5 more
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Journal of Inflammation, 2011 Background Atherosclerosis is an inflammatory disease that is marked by increased presence of Tumor Necrosis Factor-alpha (TNFα), increased expression of Vascular Cell Adhesion Molecule-1 (VCAM-1), increased presence of serum monocytes and activation of ...
Mackesy Daniel Z, Goalstone Marc L
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A causal role for hyperinsulinemia in obesity [PDF]
Journal of Endocrinology, 2017 Insulin modulates the biochemical pathways controlling lipid uptake, lipolysis and lipogenesis at multiple levels. Elevated insulin levels are associated with obesity, and conversely, dietary and pharmacological manipulations that reduce insulin have occasionally been reported to cause weight loss.
Melissa M. Page +4 more
openaire +3 more sources
Cardiovascular Diabetology, 2011 Background There is controversy about the specific pathophysiology of metabolic syndrome (MS) but several authors have argued that hyperinsulinemia is a key feature of the cluster.
Sung Ki-Chul C +3 more
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Clinical and Experimental Hypertension, 2020 Objective To investigate if insulin resistance per se or the accompanying hyperinsulinemia induced hypertension and its underlying mechanisms. Methods Sprague-Dawley rats were randomized into normal diet-fed group (ND group) and high-fat diet-fed group ...
Hui Wang +5 more
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