Results 41 to 50 of about 95,820 (339)
Indian Journal of Dermatology, 2014 Rabson-Mendenhall syndrome (RMS) is a rare genetic disorder characterized by growth retardation, dysmorphisms, lack of subcutaneous fat, acanthosis nigricans, enlarged genitalia, hirsutism, dysplastic dentition, coarse facial features, abnormal glucose ...
Iffat Hassan, Hinah Altaf, Atiya Yaseen
doaj +1 more source
Biomedicines, 2023 This opinion article highlights the potential alterations caused by insulin resistance and hyperinsulinemia on the cardiovascular system and their negative impact on heart failure (HF), and describes the potential benefits of an early screening with ...
Serafino Fazio +3 more
doaj +1 more source
Overfeeding, Autonomic Regulation and Metabolic Consequences [PDF]
, 1996 The autonomic nervous system plays an important role in the regulation of body processes in health and disease. Overfeeding and obesity (a disproportional increase of the fat mass of the body) are often accompanied by alterations in both sympathetic and ...
A Alingh Prins +65 more
core +3 more sources
Hyperinsulinemia: An Early Indicator of Metabolic Dysfunction
Journal of the Endocrine Society, 2019 Hyperinsulinemia is strongly associated with type 2 diabetes. Racial and ethnic minority populations are disproportionately affected by diabetes and obesity-related complications.
Dylan D. Thomas +3 more
semanticscholar +1 more source
The World Congress of Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC)
, 2023 Journal of Diabetes, Volume 15, Issue 1, Page 4-6, January 2023.
Zachary T. Bloomgarden
wiley +1 more source
Metabolites, 2021 The identification of insulin resistance and hyperinsulinemia in polycystic ovary syndrome (PCOS) is not a minor issue. The homeostasis model assessment of insulin resistance index (HOMA) is the most used index of IR (Insulin Resistance), validated in ...
Anna Maria Fulghesu +8 more
doaj +1 more source
Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21 [PDF]
, 2009 OBJECTIVE—Fibroblast growth factor (FGF)-21 improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes.
A. F.H. Pfeiffer +33 more
core +2 more sources
Chronic hyperinsulinemia promotes human hepatocyte senescence
Molecular Metabolism, 2022 Objective: Cellular senescence, an irreversible proliferative cell arrest, is caused by excessive intracellular or extracellular stress/damage. Increased senescent cells have been identified in multiple tissues in different metabolic and other aging ...
Ritesh K. Baboota +10 more
doaj
Children, 2023 Obesity is a multifactorial disease whose onset and development are shaped by the individual genetic background. The melanocortin 4 receptor gene (MC4R) is involved in the regulation of food intake and energy expenditure.
Joaquín Carrasco-Luna +7 more
doaj +1 more source
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]
, 2011 ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda +9 more
core +2 more sources