Results 51 to 60 of about 86,017 (262)

Adiponectin, in contrast to leptin, is not associated with body mass index, waist circumference and HOMA-IR in subjects of a west-African population [PDF]

, 2018
Factors associated with plasma levels of adiponectin and leptin were studied in adult subjects without diabetes from Cotonou in Benin (West‐Africa). Seventy (70) men and 45 women were included in the study.
Adehan, Grace, Adovoekpe, Diane, Amoussou-Guenou, Marcellin, Awede, Bonaventure, Azonbakin, Simon, Djrolo, Francois, Dossou, Emmanuel, MacFarlane, Niall G.   +7 more
core   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity

Periodontology 2000, EarlyView., 2023
Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti, Jean E. Suvan, Francesco D'Aiuto   +2 more
wiley   +1 more source

The Potential for Ketogenic Diets to Control Glucotoxicity, Hyperinsulinemia, and Insulin Resistance to Improve Fertility in Women with Polycystic Ovary Syndrome

Clinical and Experimental Obstetrics & Gynecology
Objective: This review aims to summarize the association between insulin resistance (IR) and symptoms of Polycystic Ovary Syndrome (PCOS) while explaining how nutritional interventions, specifically ketogenic diets, help manage PCOS.
Leticia Ramírez-Martínez, Cecilia Palafox-Gómez, Leonardo M. Porchia, Esther López-Bayghen   +3 more
doaj   +1 more source

Overfeeding, Autonomic Regulation and Metabolic Consequences [PDF]

, 1996
The autonomic nervous system plays an important role in the regulation of body processes in health and disease. Overfeeding and obesity (a disproportional increase of the fat mass of the body) are often accompanied by alterations in both sympathetic and ...
A Alingh Prins, A Scheurink, AB Steffens, AB Steffens, AB Steffens, AB Steffens, AB Steffens, AJW Scheurink, AJW Scheurink, AJW Scheurink, AJW Scheurink, AJW Scheurink, AJW Scheurink, AJW Scheurink, Anton B Steffens, Anton J W Scheurink, B Balkan, B Balkan, B Balkan, B Balkan, B Buwalda, B Chiang, B Jeanrenaud, BE Levin, BE Levin, Börk Balkan, C Guillaume-Gentil, C Hollenga, C Nyakas, CJ Lavie, DA York, DG Baskin, DN Brindley, E Ionescu, E Ionescu, F Rohner-Jeanrenaud, F Rohner-Jeanrenaud, F Rohner-Jeanrenaud, FW Kemmer, G Dijk Van, G Dijk Van, GA Bray, GA Bray, Gertjan van Dijk, HC Lee, HP Dustan, J Terrettaz, Jan H Strubbe, JH Strubbe, JH Strubbe, JH Strubbe, LH Storlien, LM Zucker, M Crettaz, M Modan, M Stubbs, MW Stolar, N Yamaguchi, P Havel, PD Reaven, RJ Martin, S Bass, SC Woods, SW Cushman, T Shimazu, WP Weingarten   +65 more
core   +3 more sources

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

A systematic review using the Theoretical Domains Framework to identify barriers and facilitators to the adoption of prescribing guidelines

International Journal of Pharmacy Practice, EarlyView., 2020
Abstract Objectives Evidence‐based guidelines have the potential to reduce variation and increase prescribing quality. Identifying the key determinants to their uptake, using a theory‐based approach, may assist in the design of successful interventions to increase their adoption into practice.
Paulina Paksaite, Margaret Watson, Joel Crosskey, Eni Sula, Celine West   +4 more
wiley   +1 more source