Results 51 to 60 of about 89,537 (288)

Effect of diet-induced obesity on protein expression in insulin signalling pathways of skeletal muscle in male Wistar rats [PDF]

, 2012
BACKGROUND: The prevalence of diet-induced obesity is increasing globally, and posing significant health problems for millions of people worldwide. Diet-induced obesity is a major contributor to the global pandemic of type 2 diabetes mellitus.
Abubakari, Abdul-Razak, Fatani, Sameer, Itua, Imose, Naderali, Ebrahim K., Thomas, Cecil, Wong, Christopher   +5 more
core   +2 more sources

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

The Potential for Ketogenic Diets to Control Glucotoxicity, Hyperinsulinemia, and Insulin Resistance to Improve Fertility in Women with Polycystic Ovary Syndrome

Clinical and Experimental Obstetrics & Gynecology
Objective: This review aims to summarize the association between insulin resistance (IR) and symptoms of Polycystic Ovary Syndrome (PCOS) while explaining how nutritional interventions, specifically ketogenic diets, help manage PCOS.
Leticia Ramírez-Martínez, Cecilia Palafox-Gómez, Leonardo M. Porchia, Esther López-Bayghen   +3 more
doaj   +1 more source

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

ChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva, Eucilene K. de L. B. Marques, Lidiane M. A. de Lima, Widarlane A. S. Alves, Dayane A. Gomes, Pedro L. Guzzo, Mônica F. Belian, Wagner E. Silva, Eduardo C. Lira   +8 more
wiley   +1 more source

Effects of T2DM on cancer progression: pivotal precipitating factors and underlying mechanisms

Frontiers in Endocrinology
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder affecting people worldwide. It is characterized by several key features, including hyperinsulinemia, hyperglycemia, hyperlipidemia, and dysbiosis.
Yu-Yuan Zhang, Yu-Yuan Zhang, Yong-Jiang Li, Yong-Jiang Li, Chun-Dong Xue, Chun-Dong Xue, Shen Li, Zheng-Nan Gao, Kai-Rong Qin, Kai-Rong Qin   +9 more
doaj   +1 more source

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Androgens impair β-cell function in a mouse model of polycystic ovary syndrome by activating endoplasmic reticulum stress

Endocrine Connections, 2021
Background: Androgens excess results in endoplasmic reticulum (ER) stress, which is an important cause of β cells dysfunction. Here, we investigated the molecular regulation of androgens excess, ER stress, and β-cell function in polycystic ovary syndrome
Bo Zhu, Yumei Chen, Fang Xu, Xiaolu Shen, Xuanyu Chen, Jieqiang Lv, Songying Zhang   +6 more
doaj   +1 more source

Maternal glucose and fatty acid kinetics and infant birth weight in obese women with type 2 diabetes [PDF]

, 2016
The objectives of this study were 1) to describe maternal glucose and lipid kinetics and 2) to examine the relationships with infant birth weight in obese women with pregestational type 2 diabetes during late pregnancy.
Cade, W. Todd, Cahill, Alison G, Patterson, Bruce W, Reeds, Dominic N, Tinius, Rachel A   +4 more
core   +2 more sources

Influence of insulin resistance on renal function in patients with abdominal obesity.

Medičnì Perspektivi, 2015
The purpose of the study - to assess the role of insulin resistance in the development of initial manifestations of renal disease in patients with abdominal obesity.
T. O. Pertseva, M. K. Rokutova
doaj   +1 more source