Results 61 to 70 of about 105,064 (356)
Obesity-related cognitive impairment: The role of endothelial dysfunction
Neurobiology of Disease, 2019 Obesity is a global pandemic associated with macro- and microvascular endothelial dysfunction. Microvascular endothelial dysfunction has recently emerged as a significant risk factor for the development of cognitive impairment. In this review, we present
Joy Jones Buie +3 more
doaj +1 more source
Inositols in Insulin Signaling and Glucose Metabolism [PDF]
, 2018 In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
core +1 more source
Diabetes, 2019 Although insulin resistance consistently occurs with type 1 diabetes, its predominant driver is uncertain. We therefore determined the relative contributions of hyperglycemia and iatrogenic hyperinsulinemia to insulin resistance using hyperinsulinemic ...
J. Gregory +13 more
semanticscholar +1 more source
Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity
Metabolites, 2023 In children with obesity, insulin hypersecretion is proposed to precede insulin resistance. We investigated if metformin could be used to attenuate insulin secretion from palmitate-treated isolated islets and its implication for children with obesity ...
Quan Wen +8 more
doaj +1 more source
Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]
, 2011 ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda +9 more
core +2 more sources
The FASEB Journal, 2019 Eicosapentaenoic acid (EPA) has garnered attention after the success of the REDUCE‐IT trial, which contradicted previous conclusions on EPA for cardiovascular disease risk.
A. Pal +14 more
semanticscholar +1 more source
Role of lipotoxicity in achieving glycemic control in patients with diabetes type 2 and obesity
Медицинский совет, 2013 Obesity increases the risk of diabetes mellitus type 2 due to the development of insulin resistance. Therapy for diabetes mellitus type 2 is limited by a relatively small amount of knowledge on the mechanisms of insulin resistance, despite the ...
А. S. Ametov +4 more
doaj +1 more source
Study of Serum Leptin in Well-differentiated Thyroid Carcinoma: Correlation with Patient and Tumor Characteristics [PDF]
, 2014 Background There is a proven relationship between obesity and several cancers including breast, endometrium, colorectal, and esophagus. With the increasing incidence of both obesity and thyroid cancer, we designed the present study to investigate a ...
Abdel-Aziz, TE +3 more
core +1 more source
Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
Periodontology 2000, EarlyView., 2023 Abstract Noncommunicable diseases (NCDs) are multifactorial, long‐term, chronic conditions that represent a burden to health‐care systems worldwide as they can only be controlled rather than cured; hence, they require long‐term care. With the exponential increase in NCDs, the occurrence of individuals presenting with more than one chronic disease is ...
Crystal Marruganti +2 more
wiley +1 more source
Frontiers in Physiology, 2016 Background and Purpose: Elevated sympathetic nervous system (SNS) activity is a characteristic of obesity and type 2 diabetes (T2D) that contributes to target organ damage and cardiovascular risk.
Nora E. Straznicky +10 more
doaj +1 more source