Results 91 to 100 of about 20,640 (292)

Insulin-induced lipid binding to hemoglobin [PDF]

Journal of the Serbian Chemical Society, 2003
Under hypoglycemic conditions, concomitant hyperinsulinism causes an apparent modification of hemoglobin (Hb) which is manifested by its aggregation (Niketić et al., Clin. Chim. Acta 197 (1991) 47).
Tomašević Nenad, Nikolić Milan R., Klappe Karen, Hoekstra Dick, Niketić Vesna P.   +4 more
doaj   +1 more source

Characteristics of Children and Adolescents with Hyperinsulinemia Undergoing Oral Glucose Tolerance Test: A Single-Center Retrospective Observational Study

Diseases, 2023
The aim of this study was to evaluate a potential correlation between results of the oral glucose tolerance test (OGTT) and the auxological/metabolic parameters in a cohort of overweight patients assessed for suspicion of hyperinsulinism. We analyzed 206
Clelia Cipolla, Ilaria Lazzareschi, Antonietta Curatola, Claudia Lasorella, Lucia Celeste Pane, Linda Sessa, Giulia Rotunno, Donato Rigante, Giorgio Sodero   +8 more
doaj   +1 more source

An overview of current prenatal genetic screening and diagnosis guidelines

Pregnancy, Volume 1, Issue 3, May 2025.
Abstract The landscape of prenatal genetics continues to evolve rapidly, with improvements in processing speed and technology. Clinicians are tasked with staying current with the latest recommendations for prenatal genetic screening and diagnosis in order to provide patient‐centered and evidence‐based care. We present a review of 15 societal guidelines
Carmen M. A. Santoli, Sarah K. Dotters‐Katz, Teresa N. Sparks, Jeffrey A. Kuller   +3 more
wiley   +1 more source

Hyperinsulinaemia in pregnancy and gestational outcomes: A case series

Journal of Metabolic Health, 2022
Background: Pathological insulin resistance in pregnancy is associated with an increased risk for complications such as gestational diabetes mellitus and pre-eclampsia.
Sylvia M. North, Catherine Crofts, Caryn Zinn   +2 more
doaj   +1 more source

Perspective on the Genetics and Diagnosis of Congenital Hyperinsulinism Disorders.

Journal of Clinical Endocrinology and Metabolism, 2016
CONTEXT Congenital hyperinsulinism (HI) is the most common cause of hypoglycemia in children. The risk of permanent brain injury in infants with HI continues to be as high as 25-50% due to delays in diagnosis and inadequate treatment.
C. Stanley
semanticscholar   +1 more source

Unraveling the Interplay Between Metabolism and Neurodevelopment in Health and Disease

CNS Neuroscience &Therapeutics, Volume 31, Issue 5, May 2025.
Neurodevelopment is orchestrated by precise metabolic regulation. Key metabolic processes—glucose, lipid, and amino acid metabolism—drive cell proliferation, differentiation, synaptogenesis, and neurotransmitter synthesis. These are tightly integrated with signaling pathways like mTOR, AMPK, and insulin/IGF that regulate neuronal growth and synaptic ...
Yanqing He, Kang Xie, Kang Yang, Nianhua Wang, Longbo Zhang   +4 more
wiley   +1 more source

Nouveautés radiologiques dans le dépistage et le diagnostic des erreurs innées du métabolisme [PDF]

, 2005
Les maladies héréditaires du métabolisme ont acquis une place de plus en plus importante dans la pathologie pédiatrique. Leur nombre ne cesse d’augmenter au fur et à mesure de la progression des connaissances en biologie cellulaire et des progrès ...
Boddaert, Nathalie, Brunelle, Francis, de Lonlay, Pascale, Mention, Karine, Nihoul-Fékété, Claire, Ribeiro, Maria, Touati, Guy, Valayanopoulos, Vassili   +7 more
core   +1 more source

The difficult management of persistent, non‐focal congenital hyperinsulinism: A retrospective review from a single, tertiary center

Pediatric Diabetes, 2020
Congenital hyperinsulinism (CHI) is a rare, heterogeneous disease with transient or persistent hypoglycemia. Histologically, focal, diffuse, and atypical forms of CHI exist, and at least 11 disease‐causing genes have been identified.
Amalie Greve Rasmussen, M. Melikian, E. Globa, S. Detlefsen, L. Rasmussen, H. Petersen, K. Brusgaard, A. H. Rasmussen, M. Mortensen, H. Christesen   +9 more
semanticscholar   +1 more source

Effect of a physical activity and healthy eating lifestyle intervention in pregnancy on fetal growth trajectories: The DALI randomised controlled trial

Pediatric Obesity, Volume 20, Issue 5, May 2025.
Summary Background Obesity during pregnancy is related to fetal overgrowth. Effective interventions that can mitigate this risk are needed. Objectives This study aimed to investigate the effect of a lifestyle intervention for pregnant women with obesity on fetal growth trajectories. Methods In the DALI trial, pregnant women with a body mass index ≥29.0 
Anna M. Dieberger, Mireille N. M. van Poppel, Gernot Desoye, David Simmons, Jürgen Harreiter, Roland Devlieger, Carmen Medina, Deborah A. Lawlor, Ahmed Elhakeem, on behalf of the DALI core investigator group, Gernot Desoye, David Simmons, Rosa Corcoy, Juan M. Adelantado Perez, Alexandra Kautzky‐Willer, Jürgen Harreiter, Elizabeth Mathiesen, Dorte M. Jensen, Lise Lotte T. Andersen, Fidelma Dunne, Annunziata Lapolla, Maria G. Dalfra, Alessandra Bertolotto, Mireille N. M. van Poppel, Judith G. M. Jelsma, Sander Galjaard, Ewa Wender‐Ozegowska, Agnieszka Zawiejska, David Hill, Roland Devlieger, Frank J. Snoek   +30 more
wiley   +1 more source

Patologia molecular do receptor de sulfoniluréia (SUR1) [PDF]

, 2000
The sulfonylurea receptor is a subunit of the ATP-sensitive potassium channel, which is expressed in the pancreatic beta cell. The central role of this receptor in glucose-induced insulin secretion was confirmed by description that mutations in this gene
Reis, André Fernandes [UNIFESP], Velho, Gilberto [UNIFESP]   +1 more
core   +2 more sources