Results 61 to 70 of about 14,011 (206)

Childhood Type II Diabetes: The Risks and Complications [PDF]

open access: yes, 2015
Type II Diabetes Mellitus is an endocrine disorder that affects people of all ages. Type II Diabetes was once considered adult-onset diabetes, as it was nearly exclusively diagnosed in adults. Over the last three decades, the number of children diagnosed
Kapke, Danielle R
core   +1 more source

Prognostic value of triglyceride‐derived metabolic parameters for micro‐ and macrovascular complications and mortality in individuals with type 2 diabetes: The Rio de Janeiro type 2 diabetes cohort study

open access: yesDiabetic Medicine, Volume 43, Issue 4, April 2026.
Prognostic value of triglyceride‐derived metabolic parameters for micro‐ and macrovascular complications and mortality in individuals with type 2 diabetes. Abstract Aims Triglyceride‐derived metabolic parameters have been proposed as indirect measures of insulin resistance and also as predictors of worse prognosis, mainly in Asian populations. However,
Claudia R. L. Cardoso   +3 more
wiley   +1 more source

Characteristics of Children and Adolescents with Hyperinsulinemia Undergoing Oral Glucose Tolerance Test: A Single-Center Retrospective Observational Study

open access: yesDiseases, 2023
The aim of this study was to evaluate a potential correlation between results of the oral glucose tolerance test (OGTT) and the auxological/metabolic parameters in a cohort of overweight patients assessed for suspicion of hyperinsulinism. We analyzed 206
Clelia Cipolla   +8 more
doaj   +1 more source

Rapid intraoperative insulin assay: a novel method to differentiate insulinoma from nesidioblastosis in the pediatric patient [PDF]

open access: yes, 2007
Introduction: Hyperinsulinism is the most common cause of recurrent and persistent hypoglycemia in infancy and childhood. Causes can include nesidioblastosis, pancreatic islet cell tumors such as insulinoma, and associations with multiple endocrine ...
Vivian E Strong   +20 more
core   +2 more sources

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio   +12 more
wiley   +1 more source

Insulin-secreting tumors of the islets of Langerhans [PDF]

open access: yes, 1958
Thesis (M.D.)—Boston ...
Robert Rodman
core  

Successful use of long acting octreotide in two cases with Beckwith-Wiedemann syndrome and severe hypoglycemia [PDF]

open access: yes, 2014
INTRODUCTION: Hyperinsulinism associated with Beckwith-Wiedemann syndrome (BWS) can occur in about 50% of cases, causing hypoglycemia of variable severity. Parenteral use of octreotide may be indicated if unresponsive to diazoxide.
Hiba Al-Zubeidi   +2 more
core   +1 more source

Insulinoma in a Young Patient With Focal Seizures: A Case Report of a Neurological Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Insulinomas can mimic refractory epilepsy, leading to diagnostic delays. Hypoglycemia should be ruled out in patients with fasting‐associated focal seizures. Timely diagnosis via Whipple's triad and surgical resection offers a complete cure and reversal of neuropsychiatric symptoms.
María Valerio López   +5 more
wiley   +1 more source

Estudio PET-TC con 18F-fluoro-L-DOPA combinado con el análisis genético para la optimización de la clasificación y tratamiento de un niño con hiperinsulinismo congénito grave [PDF]

open access: yes, 2009
BACKGROUND: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in infancy. The differential diagnosis between focal and diffuse forms of CHI is of great importance when planning surgery. The aim of this article is to
Arbizu, J. (Javier)   +6 more
core  

Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism

open access: yes
International Journal of Gynecology &Obstetrics, EarlyView.
Emma Bertucci   +10 more
wiley   +1 more source

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