Results 211 to 220 of about 116,541 (302)

Clinical Significance of Biomarkers in Oropharyngeal Squamous Cell Carcinoma: Recurrence Prediction and Treatment Response

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Oropharyngeal squamous cell carcinoma (OPSCC) accounts for a substantial proportion of head and neck cancers, with a rising incidence largely driven by human papillomavirus (HPV) infection. Despite advances in multimodal treatment, disease recurrence remains common and limits long‐term survival, highlighting the need for reliable ...
Yunxia Chen, Wenyu Zhang, Xiang Gao, Kongling Xing, Yijing Ren, Jinyu Hu, Zhihao Xie, Ping Zhou   +7 more
wiley   +1 more source

Molecular Links Between Smoking, COPD, and Lung Cancer: A DNA Methylation Perspective. [PDF]

Cancers (Basel)
Forigua CB, Bermúdez LG, Cañas Arboleda A, Ariza RR, Roldán MT, Morales MT, González Cubides DM, Rojas A.   +7 more
europepmc   +1 more source

Decoding the Oncogenic Role of USP22 Through Pan‐Cancer Genomic and Epigenetic Analysis

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Ubiquitin‐specific protease 22, an important catalytic component of the human SAGA (Spt‐Ada‐GcN5 Acetyltransferase) complex, regulates the deubiquitination and methylation of histones, which in turn influences gene expression. Its overexpression alters gene regulation, transcription, cancer progression, and therapy resistance.
Uma Devi A., Prakash Kumar Shukla
wiley   +1 more source

Emerging Roles of Adenosine Metabolism in Astrocytes During Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
Adenosine, as a key metabolic and neurotransmitter in the brain, has become an important therapeutic target for improving the efficacy of immunotherapy for stroke. However, gaps in knowledge about its metabolic pathways have become a key factor limiting its clinical translation.
Shu Zhu, Shanshan Zhong, Xiaoru Lin, Chuansheng Zhao, Yugang Li   +4 more
wiley   +1 more source

Hypermethylation-mediated silencing of RASD1 drives multiple myeloma pathogenesis. [PDF]

Blood Res
Yi C, Ren N, Cai Y, Zhang J, Feng Y.
europepmc   +1 more source

Mild Photoperiod and Temperature Fluctuations Elicit Tissue‐Specific DNA Methylation Changes in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 6, Page 3151-3154, June 2026.
Ji Hoon Rhee, Hyogi Kim, Hyodong Lee, Yunji Jeon, Yeonhee Choi   +4 more
wiley   +1 more source

A multi‐centre, prospective trial of a methylation‐based liquid biopsy for early detection of liver cancer in high‐risk populations

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Three hypermethylated cfDNA markers specific to liver cancer, RNF135, CHFR and PAX5, were identified in peripheral blood and used to construct a diagnostic model. The model achieved 94.43% sensitivity and 95.16% specificity in a large clinical validation cohort, with a sensitivity of 93.1% for stage‐I liver cancer. Abstract Background and aims Existing
Ruohan Zhang, Xinrong Yang, Guangming Li, Yinan Deng, Jibing Liu, Hongjun Gao, Jie Zhao, Jianwen Cheng, Xiaofei Zhao, Yang Yang, Zhen Wu, Shuangzhen Gu, Yang Wu, Zhongying Ma, Yanli Liu, Yan Kang, Guangpeng Zhou, Hua Li, Yonghong Zhang, Xiaoliang Han, Jia Fan, Jian Zhou, Kefeng Dou, Kaishan Tao   +23 more
wiley   +1 more source

The Effects of <i>BRCA1</i> and <i>BRCA2</i> Promoter Methylation on Clinicopathological Characteristics and Clinical Outcomes in HGSOC. [PDF]

Cells
Živić K, Boljević I, Nedeljković M, Matović M, Janković R, Tanić M.   +5 more
europepmc   +1 more source

Trends and Research Hotspots in Biomarkers of Sjögren's Syndrome Over the Past Two Decades: A Data‐Driven Atlas Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background Sjögren's syndrome (SS) is a chronic, systemic inflammatory disorder primarily characterized by dry eyes and dry mouth, often involving multiple organ systems. The disease's heterogeneous clinical presentation and the absence of non‐invasive, specific biomarkers complicate its diagnosis and prognostic assessment.
Xinyan Zhang, Huan Li, Xueqing Zhou, Shangwen Qi, Songwei Li   +4 more
wiley   +1 more source

Effects of obesity on DNA methylation and DNA methyltransferases in the reproductive system. [PDF]

Histochem Cell Biol
Şükür G, Çınar Ö, Uysal Çınar F.
europepmc   +1 more source