Results 211 to 220 of about 70,734 (243)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, Volume 13, Issue 48, 28 August 2026.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Genome-Wide DNA Methylation Profiling Reveals Ancestry-Associated Epigenetic Reprogramming in Cervical Intraepithelial Neoplasia. [PDF]

Int J Mol Sci
Masoud M, Shastri C, Banerjee R, Dasgupta S, Chavarria-Bernal H, Singh KP, Pierce JY, Dasgupta S.   +7 more
europepmc   +1 more source

Hypermethylation-mediated silencing of RASD1 drives multiple myeloma pathogenesis. [PDF]

Blood Res
Yi C, Ren N, Cai Y, Zhang J, Feng Y.
europepmc   +1 more source

Methylation-driven Cancer Genes and Methylation Profiling in Glioma: A Comparative Study between East Asian and non-Hispanic White Populations

Newman L, Dunne N, Cheng VW, Sharma-Oates A.   +3 more
europepmc   +1 more source

<i>CDKN2A</i>/<i>p16</i> Exon 2 Hypermethylation in Lung Squamous Cell Carcinoma Associated with Interstitial and Emphysematous Lung Diseases: A Comparative Analysis of Tumor, Adjacent and Distant Lung Tissues. [PDF]

Curr Oncol
Miyakawa K, Oyama K, Liu J, Akiyama N, Sakata A, Hayashi M, Kamikokura Y, Aoki N, Yuzawa S, Ichihara S, Sasaki T, Kitada M, Mizukami Y, Tanino M.   +13 more
europepmc   +1 more source

DNA methylation at OsAmy3E promoter is involved in grain quality under heat stress in rice (Oryza sativa L.). [PDF]

Sci Rep
Chen WJ, Suriyasak C, Nong HT, Oyama Y, Kobayashi T, Matsumoto R, Kawaguchi R, Yang X, Miyahara K, Hamaoka N, Ishibashi Y.   +10 more
europepmc   +1 more source

Deciphering epigenetic crosstalk in multiple myeloma pathogenesis and treatment. [PDF]

Clin Epigenetics
Alipoor SD, Shrestha M, Liu A, Chang H.
europepmc   +1 more source

The Effects of <i>BRCA1</i> and <i>BRCA2</i> Promoter Methylation on Clinicopathological Characteristics and Clinical Outcomes in HGSOC. [PDF]

Cells
Živić K, Boljević I, Nedeljković M, Matović M, Janković R, Tanić M.   +5 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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Hypermethylation and Carcinogenesis

Science, 2002
In cancer cells, abnormal methylation patterns of DNA sequences are often present. By examining the role of the PML-RAR fusion gene, a well-studied translocation in leukemia, Di Croce et al . demonstrate that transcriptional silencing in cancer cells can occur through the ...
  +4 more sources