Results 91 to 100 of about 1,815 (189)

Prevalence and Molecular Characterization of Carbapenemase and Hypervirulence Genes in Klebsiella pneumoniae Isolates in Hospitals of Benghazi, Libya

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is a leading cause of hospital‐acquired infections, particularly in intensive care units (ICUs), where multidrug‐resistant (MDR) and hypervirulent strains represent major therapeutic challenges. This study investigated the phenotypic and molecular features of isolates recovered from ICU patients and the hospital environment in ...
Sherif Asolimany, Raoudha Dziri, Ghada Ochi, Mohamed Iheb Ben Tekfa, Ghassan Tayh, Asma Elramli, Oumayma Kenza Chabbar, Hadda-Imene Ouzari, Naouel Klibi, Divakar Sharma   +9 more
wiley   +1 more source

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important emerging pathogen leading to serious clinical outcomes as the multidrug‐resistant (MDR) isolates arise. While K. pneumoniae is a well‐known pathogen in human clinical settings, its risks in nonhuman hosts and potential for cross‐species transmission remain poorly understood. In this study, we performed whole‐genome
Qiu Xu, Cuilong Fan, Yaowei Liu, Xiaofeng Lu, Wei Song, Susu Du, Yao Zhu, Fang Xie, Wanjiang Zhang, Zhong Peng   +9 more
wiley   +1 more source

Clinical and Molecular Characteristics of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolates in a Tertiary Hospital in Shanghai, China

Infection and Drug Resistance, 2021
Cong Zhou,1 Qiang Wu,1 Leqi He,1 Hui Zhang,1 Maosuo Xu,1 Baoyu Yuan,2 Zhi Jin,3 Fang Shen1 1Department of Clinical Laboratory Medicine, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Clinical ...
Zhou C, Wu Q, He L, Zhang H, Xu M, Yuan B, Jin Z, Shen F   +7 more
doaj  

Hypervirulent Klebsiella pneumoniae as Unexpected Cause of Fatal Outbreak in Captive Marmosets, Brazil

Emerging Infectious Diseases, 2020
After the sudden death of captive marmosets in São Paulo, Brazil, we conducted a histologic and microbiologic study. We found hyperacute septicemia caused by hypermucoviscous sequence type 86 K2 Klebsiella pneumoniae.
Juliana Mariotti Guerra, Natália Coehlo Couto de A. Fernandes, Alessandra Loureiro Morales dos Santos, Joana de Souza Pereira Barrel, Bruno Simões Sergio Petri, Liliane Milanelo, Monique Ribeiro Tiba-Casas, Alcina Maria Liserre, Cláudia Regina Gonçalves, Cláudio Tavares Sacchi, José Luiz Catão-Dias, Carlos Henrique Camargo   +11 more
doaj   +1 more source

A Fatal Case of Necrotizing Pneumonia Caused by Hypermucoviscous Klebsiella pneumoniae

Clinical Case Reports
ABSTRACTNecrotizing pneumonia has a high mortality rate of approximately 50%. Its computed tomography findings lack enhancement in areas of consolidation. These findings should be interpreted as potentially indicative of a severe clinical course. Hypermucovisous strains of Klebsiella pneumoniae are often hypervirulent and may cause fatal necrotizing ...
Kaori Ishiyama, Kyohei Miyamoto, Nozomu Shima, Shigeaki Inoue   +3 more
openaire   +3 more sources

Epidemiological and Genomic Characteristics of blaCTX-M and blaNDM‐Producing K. pneumoniae From Dairy Cows in Henan Province, China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Extended‐spectrum β‐lactamase (ESBL) and carbapenemase‐producing Klebsiella spp., particularly K. pneumoniae, are emerging threats in both clinical and community settings. To investigate the epidemiology, phylogenetics, and antimicrobial resistance of bovine‐origin strains, 174 bacterial isolates were obtained from 180 mastitic milk samples across ...
Yiming Feng, Wenfeng Li, Mengjuan Ma, Yajun Zhai, Hua Wu, Jianhua Liu, Gongzheng Hu, Dandan He, Yushan Pan, Zhong Peng   +9 more
wiley   +1 more source

Image_1_Clinical and genomic analysis of hypermucoviscous Klebsiella pneumoniae isolates: Identification of new hypermucoviscosity associated genes.tif

, 2023
IntroductionHypermucoviscous Klebsiella pneumoniae (HmKp) poses an emerging and highly pathogenic global health threat. This study aimed to investigate the clinical and genomic characteristics of HmKp isolates to better understand the virulence ...
Jiali Chen (5696), Jinpeng Guo (3594161), Yue Tang (235893), Boan Li (283471), Fangni Liu (14324568), Xiong Liu (43564), Yong Wang (12837), Shiyu Qin (4977539), Meiling Jin (3975752), Yong Chen (109188), Meitao Yang (12641440), Changjun Wang (16132), Tianye Jia (210440), Na Zhang (333280), Xiaojing Yang (154840)   +14 more
core   +1 more source

Characterization and Therapeutic Potential of a Novel Lytic Bacteriophage vB_Kp_H122 Targeting Multidrug‐Resistant Hypervirulent Klebsiella pneumoniae of K57 Capsular Type

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important zoonotic opportunistic pathogen. Of particular concern is the emergence of multidrug‐resistant hypervirulent K. pneumoniae (MDR‐hvKP), which represents a serious public health threat. Bacteriophage (phage) therapy has emerged as a promising solution to combat antibiotic‐resistant K. pneumoniae infections.
Cuilong Fan, Qiu Xu, Stefan Schwarz, Yaowei Liu, Susu Du, Xiaofeng Lu, Yuxuan Yuan, Longhua Lin, Shuangyu Xie, Fang Xie, Wanjiang Zhang, Anusak Kerdsin   +11 more
wiley   +1 more source

Septic arthritis subsequent to urosepsis caused by hypermucoviscous Klebsiella pneumoniae.

Internal medicine (Tokyo, Japan), 2013
We herein report the first case of septic arthritis caused by rmpA-positive hypermucoviscous community-acquired K. pneumoniae that followed urosepsis in a 65-year-old Japanese woman. The patient responded well to drainage of the abscesses and treatment with cefazolin. Although this virulent phenotype of K. pneumoniae has been primarily reported in Hong
Suzuki, Kei, Nakamura, Akiko, Enokiya, Tomoyuki, Iwashita, Yoshiaki, Tomatsu, Eri, Muraki, Yuichi, Kaneko, Toshihiro, Okuda, Masahiro, Katayama, Naoyuki, Imai, Hiroshi   +9 more
openaire   +2 more sources

Antibacterial and Antibiotic‐Enhancing Activity of 3‐Hydroxy‐4‐methoxycinnamic Acid: Experimental Data and In Silico Predictions

ChemistrySelect, Volume 10, Issue 47, December 15, 2025.
ABSTRACT The growing bacterial resistance, driven by the inappropriate use of antibiotics, poses a global health threat and demands new therapeutic strategies. Natural phenolic compounds, such as 3‐hydroxy‐4‐methoxycinnamic acid (3H4MCA), stand out due to their antimicrobial and antioxidant properties, showing potential in combating resistant pathogens.
José Thyálisson da Costa Silva, Viviane Bezerra da Silva, Guilherme Fernandes Teixeira, Carlos Alonso Leite dos Santos, Antonia Adeublena de Araujo Monteiro, Janaína Esmeraldo Rocha, Ewerton Yago de Sousa Rodrigues, Rafael Pereira da Cruz, Isaac Moura Araújo, Adrielle Rodrigues Costa, Cicera Laura Roque Paulo, Irwin Rose Alencar de Menezes, Maria Flaviana Bezerra Morais‐Braga, José Maria Barbosa‐Filho, Saulo Almeida de Menezes, Henrique Douglas Melo Coutinho, José Weverton Almeida‐Bezerra   +16 more
wiley   +1 more source