Results 11 to 20 of about 41,556 (244)
Hyperoxia in Extreme Hemodilution [PDF]
European Surgical Research, 2002 Intraoperative surgical blood loss is initially replaced by infusion of red cell-free, cristalloidal or colloidal solutions. When normovolemia is maintained the ensuing dilutional anemia is compensated by an increase of cardiac output and of arterial oxygen extraction.
Habler, Oliver +3 more
openaire +6 more sources
Critical Care, 2021 AbstractOxygen (O2) toxicity remains a concern, particularly to the lung. This is mainly related to excessive production of reactive oxygen species (ROS).Supplemental O2, i.e. inspiratory O2concentrations (FIO2) > 0.21 may causehyperoxaemia(i.e. arterial (a) PO2 > 100 mmHg) and, subsequently,hyperoxia(increased tissue O2concentration), thereby ...
Mervyn Singer +7 more
openaire +7 more sources
European Psychiatry, 2021 IntroductionSeveral studies of normobaric hyperoxia in some neurological conditions have demonstrated clinical benefits. Oxygen enriched air may increase oxygen pressure in brain tissue and have biochemical effects such as on brain erythropoietin gene expression, even in patients without lung disease.ObjectivesThis pilot, randomized, double-blind study
R. Belmaker +5 more
openaire +2 more sources
Anti-placental growth factor antibody ameliorates hyperoxia-mediated impairment of lung development in neonatal rats [PDF]
Brazilian Journal of Medical and Biological Research, 2020 This study investigates the effect of the overexpression of the placental growth factor (PGF) and hyperoxia on lung development and determines whether anti-PGF antibody ameliorates hyperoxia-mediated impairment of lung development in newborn rats.
Zhiqun Zhang +4 more
doaj +1 more source
Hyperoxia and the Immature Brain [PDF]
Developmental Neuroscience, 2016 Despite major advances in obstetrics and neonatal intensive care, preterm infants frequently suffer from neurological impairments in later life. Preterm and also full-term neonates are generally susceptible to injury caused by reactive oxygen species due to the immaturity of endogenous radical scavenging systems.
Reich, Bettina +3 more
openaire +3 more sources
SFTA2 - a novel secretory peptide highly expressed in the lung - is modulated by lipopolysaccharide but not hyperoxia [PDF]
, 2012 Tissue-specific transcripts are likely to be of importance for the corresponding organ. While attempting to define the specific transcriptome of the human lung, we identified the transcript of a yet uncharacterized protein, SFTA2.
Bretschneider, Nancy +9 more
core +11 more sources
Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke [PDF]
, 2018 The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients.
Brennan, David +5 more
core +1 more source
Hyperoxia Induced Hypomyelination
Biomedicines, 2022 We asked whether hyperoxia might induce hypomyelination of the corpus callosum, clinically described as periventricular leukomalacia (PVL) of the severely preterm infant. Mouse pups and their nursing dams were placed in 80% oxygen from P4-P8, then removed to room air until P11.
Weilin Song +4 more
openaire +3 more sources
Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis [PDF]
, 2013 Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants.
Audi, Said H. +6 more
core +3 more sources
Experimental Biology and Medicine, 1973 SummaryExposure to a 50% oxygen environment produced a decrease in erythropoiesis which was paralleled by a decrease in plasma erythropoietic stimulating activity. Similar results were obtained following exposure to a 100% oxygen environment. Marrow depression produced by hyperoxia could be reversed by erythropoietic stimulants.
J W, Fletcher +3 more
openaire +2 more sources