Results 31 to 40 of about 28,027 (244)

Hyperoxia in acute asthma [PDF]

open access: yesThorax, 2011
We read with interest the recent article ‘Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma’ by Perrin et al 1 and the accompanying editorial. We note that data presented in the online supplement suggest, unsurprisingly, response to treatment at 60 min in terms of respiratory rate and ...
Catherine, Snelson, Bill, Tunnicliffe
openaire   +2 more sources

Ketamine exacerbates cortical neuroapoptosis under hyperoxic conditions by upregulating expression of the N-methyl-D-aspartate receptor subunit NR1 in the developing rat brain

open access: yesBMC Anesthesiology, 2018
Background Ketamine and hyperoxia are widely used in obstetric and pediatric settings. Either ketamine or hyperoxia has been reported to cause neuroapoptosis in the developing brain, and ketamine-induced neuronal apoptosis may involve a compensatory ...
Changyi Wu   +3 more
doaj   +1 more source

Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury

open access: yesRespiratory Research, 2022
Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature infants that may cause long-term lung dysfunction. Accumulating evidence supports the vascular hypothesis of BPD, in which lung endothelial cell dysfunction drives this ...
Jason L. Chang   +7 more
doaj   +1 more source

Heat shock protein 70 protects the lungs from hyperoxic injury in a neonatal rat model of bronchopulmonary dysplasia.

open access: yesPLoS ONE, 2023
Hyperoxia plays a significant role in the pathogenesis of lung injury, such as bronchopulmonary dysplasia (BPD), in premature infants or newborns. BPD management aims to minimize further injury, provide an optimal environment to support growth and ...
Cheng-Han Lee   +5 more
doaj   +1 more source

Oxygen Variations—Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia—Is the Dose the Clue?

open access: yesInternational Journal of Molecular Sciences, 2023
Molecular oxygen (O2) is one of the four most important elements on Earth (alongside carbon, nitrogen and hydrogen); aerobic organisms depend on it to release energy from carbon-based molecules [...]
Costantino Balestra   +2 more
openaire   +4 more sources

Hyperoxia-induced mitochondrial hyperpolarization.

open access: yes, 2017
(A) Fold-change in TMRE fluorescence intensity of A549 cells cultured in hyperoxia in the absence or presence of 0.5 μM FCCP. (B) TMRE fluorescence intensity after 3 days hyperoxic culture following lentiviral transduction of NT, Trx2, or Prx3 shRNAs in ...
Darwin R. Daugaard (3611930)   +6 more
core   +1 more source

Hyperoxia shows duration-dependent effects on the lengths of cell cycle phases in fetal cortical neural stem cells

open access: yesFrontiers in Cell and Developmental Biology
Fetal neural stem cells (NSCs) physiologically reside under low-oxygen conditions (1%–5% of tissue pO2), but are often transferred and maintained under atmospheric oxygen levels of 21% pO2 (hyperoxia) for in vitro investigations.
Jennifer Lanto   +5 more
doaj   +1 more source

Postnatal hyperoxia or DEHP exposure leads to growth restriction and delayed lung development in newborn rats

open access: yesPediatrics and Neonatology, 2018
Background: Di-(2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in many medical devices. We previously showed that maternal DEHP exposure led to restricted growth and delayed lung maturation in newborn rats.
Zhong-Jie Liang   +5 more
doaj   +1 more source

Evaluation of ERK activity on Ischemic Tolerance-induced by Preconditioning with Intermittent Normobaric Hyperoxia in the Rat Model of Stroke [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: Recent studies indicate that hyperoxia has a significant therapeutic effect in the acute ischemic injury. The role of intracellular kinases, including ERK, has been posed in the phenomenon of ischemic tolerance.
Firoozeh Alavian   +3 more
doaj  

Protective Effect of Dexmedetomidine against Hyperoxia-Damaged Cerebellar Neurodevelopment in the Juvenile Rat

open access: yesAntioxidants, 2023
Impaired cerebellar development of premature infants and the associated impairment of cerebellar functions in cognitive development could be crucial factors for neurodevelopmental disorders. Anesthetic- and hyperoxia-induced neurotoxicity of the immature
Robert Puls   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy