Results 121 to 130 of about 3,251 (194)
Measurement and interpretation of central venous pressure: a narrative review
Summary Introduction Central venous pressure has been a key component of haemodynamic monitoring for several decades, but its clinical utility is still debated. While central venous pressure has been used traditionally to assess intravascular volume status and fluid responsiveness, mounting evidence suggests that its absolute value alone is an ...
Patryck Lloyd‐Donald+3 more
wiley +1 more source
Ultrasound Assessment of Venous and Pulmonary Congestion in Left Ventricular Assist Devices Patients
Renal venous stasis index (RVI) of Doppler renal ultrasound index is the peripheral vein ultrasound associated with high right atrial pressure, and right displacement of the interatrial septum is the echocardiographic parameter associated with high pulmonary wedge pressure.
Attilio Iacovoni+8 more
wiley +1 more source
HCV clearance during direct‐acting antiviral therapy rapidly increases serum lipids and lipoproteins, potentially elevating cardiovascular risk. These metabolic changes, mediated by genes regulating hepatic lipogenesis, suggest that lipid levels should be closely monitored post‐SVR to assess long‐term cardiovascular implications.
Zahra Sarrafan‐Chaharsoughi+12 more
wiley +1 more source
New‐onset DM occurred in 13% of patients with AIH, was related to older age, non‐Caucasian ethnicity, higher prednisolone dose, higher BMI at diagnosis and weight gain and was an independent predictor of all‐cause death/transplantation and of cirrhosis development, underlining the need to minimise steroid burden in AIH.
Sarah Flatley+6 more
wiley +1 more source
The ABID‐LSM score, a combination of liver stiffness measurement and easily obtainable clinical and laboratory factors, can accurately predict the risk of hepatic decompensation in patients with MASLD and cirrhosis. ABSTRACT Background & Aims Predicting the risk of hepatic decompensation guides prognostication and therapy; however, it is challenging in
Luis Calzadilla Bertot+14 more
wiley +1 more source
Progressive hepatopathy after central division hepatectomy in a dog
The consequences of large‐volume hepatectomy on the remaining liver in the dog are not documented. This case report documents a progressive hepatopathy after central division hepatectomy in a 10‐year‐old female Lhasa Apso dog. Serum biochemistry at presentation for chronic urinary incontinence indicated a hepatopathy, with a liver mass identified on ...
SJ Wood, GL Hosgood, F Coiacetto
wiley +1 more source
PI3Kδ Inhibitor Parsaclisib in Japanese Patients With Relapsed or Refractory Follicular Lymphoma
CITADEL‐213 evaluated the efficacy and safety of parsaclisib (PI3Kδ inhibitor) in Japanese patients with relapsed or refractory follicular lymphoma (R/R FL). The objective response rate was 88.1%, with 23.8% of patients experiencing a complete response and 64.3% experiencing a partial response; treatment‐emergent adverse events led to parsaclisib ...
Noriko Fukuhara+15 more
wiley +1 more source
NSun2‐Mediated tsRNAs Alleviate Liver Fibrosis via FAK Dephosphorylation
NSun2 deficiency inhibited sinusoidal capillarization, alleviating liver fibrosis. Reduced NSun2 expression led to alterations in the functional tsRNAs tRF‐1‐S25 and tRF‐5‐V31, which regulate sinusoidal capillarization by targeting key proteins, including DUSP1 and FAK – crucial clinical targets – offering a novel RNA‐based therapeutic approach for ...
Pengcheng Li+14 more
wiley +1 more source