Results 141 to 150 of about 4,353 (174)

Emergence of Carbapenemase-Producing Hypervirulent Klebsiella pneumoniae in Switzerland

Antimicrobial Agents and Chemotherapy, 2023
Increasing occurrence of multidrug-resistant (MDR) and hypervirulent (hv) Klebsiella pneumoniae (MDR-hvKp) convergent clones is being observed. Those strains have the potential of causing difficult-to-treat infections in healthy adults with an increased capacity for mortality.
Otávio Hallal Ferreira Raro, Patrice Nordmann, Manuel Dominguez Pino, Jacqueline Findlay, Laurent Poirel   +4 more
openaire   +2 more sources

Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae

The Lancet Infectious Diseases, 2016
Klebsiella pneumoniae is the most clinically relevant species of this genus, known to cause both community-acquired and nosocomial infections worldwide. In the past two decades, a distinct hypervirulent strain of K pneumoniae, characterised by its hypermucoviscous phenotype, has emerged as a clinically significant pathogen responsible for highly ...
Bonnie C, Prokesch, Michael, TeKippe, Jiwoong, Kim, Prithvi, Raj, Erin McElvania, TeKippe, David E, Greenberg   +5 more
openaire   +2 more sources

Hypervirulent Klebsiella Pneumoniae Osteomyelitis in a Child

Pediatric Infectious Disease Journal
An 18-month-old boy presented with septic arthritis and osteomyelitis caused by Hypervirulent Klebsiella pneumoniae harboring cardinal virulence genes. The condition necessitated several surgical interventions, and a prolonged course of antibiotic therapy to effectively manage the severe infection and prevent complications, highlighting the challenges ...
Ryoichi Yamaki, Yusuke Isobe, Yuto Otsubo, Kohji Komori, Sohei Harada, Hiroshi Hataya, Yuho Horikoshi   +6 more
openaire   +2 more sources

Evolutionary transition of hypervirulent Klebsiella pneumoniae to multidrug-resistant hypervirulent Klebsiella pneumoniae: Indian experience

Indian Journal of Medical Microbiology
An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni, Jobin John Jacob, V. Aravind, T. Praveen, Karthik Gunasekaran, Binesh Lal Y, Kamini Walia, Balaji Veeraraghavan   +7 more
openaire   +2 more sources

Investigations of carbapenem resistant and hypervirulent Klebsiella pneumoniae

Acta Microbiologica et Immunologica Hungarica
AbstractHypervirulent Klebsiella pneumoniae is an emerging pathogen that has gained attention due to its increased ability to cause infections even in healthy individuals. The aim of this study is to investigate virulence factors in K. pneumoniae strains isolated from clinical specimens and their association with carbapenem resistance.
El Mehdi Belouad, Elmostafa Benaissa, Nadia El Mrimar, Yassine Eddair, Adil Maleb, Mostafa Elouennass   +5 more
openaire   +3 more sources

Seven hypervirulent ST380 Klebsiella pneumoniae septic localizations

Médecine et Maladies Infectieuses, 2017
International ...
Hentzien, Maxime, Rosman, J., Decré, D., Brenkle, K., Mendes-Martins, L., Mateu, P.   +5 more
openaire   +3 more sources

Pediatric hypervirulent Klebsiella pneumoniae septic arthritis

Pediatrics International, 2016
AbstractCases of infection with hypervirulent Klebsiella pneumoniae are gradually increasing in number, and cause life‐threatening community‐acquired infection even in immunocompetent patients. A 14‐year‐old boy developed septic hip arthritis due to hypervirulent K. pneumoniae (sequence type 23, serotype K1, magA positive). The patient initially seemed
Shun, Kishibe, Yusuke, Okubo, Saeko, Morino, Shintaro, Hirotaki, Tomoyuki, Tame, Kotaro, Aoki, Yoshikazu, Ishii, Norikazu, Ota, Satoshi, Shimomura, Hiroshi, Sakakibara, Toshiro, Terakawa, Yuho, Horikoshi   +11 more
openaire   +2 more sources

Emphysematous gastritis due to hypervirulent Klebsiella pneumoniae

The Lancet Infectious Diseases, 2022
Naomi, Saeki, Kentaro, Takei, Ken, Katsuta, Akihiko, Nakasato, Hiroaki, Baba, Kengo, Oshima, Koichi, Tokuda, Shigeki, Kushimoto, Hajime, Kanamori   +8 more
openaire   +2 more sources

Clinical and laboratory insights into the threat of hypervirulent Klebsiella pneumoniae

International Journal of Antimicrobial Agents
Hypervirulent Klebsiella pneumoniae (hvKP) typically causes severe invasive infections affecting multiple sites in healthy individuals. In the past, hvKP was characterized by a hypermucoviscosity phenotype, susceptibility to antimicrobial agents, and its tendency to cause invasive infections in healthy individuals within the community.
Xinhong Han, Jiayao Yao, Jintao He, Haiyang Liu, Yan Jiang, Dongdong Zhao, Qiucheng Shi, Junxin Zhou, Huangdu Hu, Peng Lan, Hua Zhou, Xi Li   +11 more
openaire   +2 more sources

New insights and perspectives on the virulence of hypervirulent Klebsiella pneumoniae

Folia Microbiologica
Klebsiella pneumoniae, a Gram-negative bacterium, comprises strains with diverse virulence potentials, ranging from classical to hypervirulent variants. Understanding the genetic basis underlying the virulence disparities between hypervirulent (hvKp) and classical K. pneumoniae (cKp) strains is crucial.
Ifeanyi Elibe Mba, Toluwalase Odunayo Mba, Chibuzor Kenneth Uwazie, Fetuata Aminat Aina, Akindele Oluwaseun Kemisola, Ijeoma Josephine Uwazie   +5 more
openaire   +2 more sources