Results 191 to 200 of about 7,114 (212)

Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae

The Lancet Infectious Diseases, 2016
Klebsiella pneumoniae is the most clinically relevant species of this genus, known to cause both community-acquired and nosocomial infections worldwide. In the past two decades, a distinct hypervirulent strain of K pneumoniae, characterised by its hypermucoviscous phenotype, has emerged as a clinically significant pathogen responsible for highly ...
Bonnie C, Prokesch, Michael, TeKippe, Jiwoong, Kim, Prithvi, Raj, Erin McElvania, TeKippe, David E, Greenberg   +5 more
openaire   +2 more sources

Evolutionary transition of hypervirulent Klebsiella pneumoniae to multidrug-resistant hypervirulent Klebsiella pneumoniae: Indian experience

Indian Journal of Medical Microbiology
An emerging pathotype of Klebsiella pneumoniae, initially identified in Southeast Asian countries, has now spread to multiple countries, including India. These convergent strains, carrying both resistance and virulence determinants, are classified as multidrug-resistant Hypervirulent Klebsiella pneumoniae (MDR-HvKp).
Sanika Mahesh Kulkarni, Jobin John Jacob, V. Aravind, T. Praveen, Karthik Gunasekaran, Binesh Lal Y, Kamini Walia, Balaji Veeraraghavan   +7 more
openaire   +2 more sources

Pediatric hypervirulent Klebsiella pneumoniae septic arthritis

Pediatrics International, 2016
AbstractCases of infection with hypervirulent Klebsiella pneumoniae are gradually increasing in number, and cause life‐threatening community‐acquired infection even in immunocompetent patients. A 14‐year‐old boy developed septic hip arthritis due to hypervirulent K. pneumoniae (sequence type 23, serotype K1, magA positive). The patient initially seemed
Shun, Kishibe, Yusuke, Okubo, Saeko, Morino, Shintaro, Hirotaki, Tomoyuki, Tame, Kotaro, Aoki, Yoshikazu, Ishii, Norikazu, Ota, Satoshi, Shimomura, Hiroshi, Sakakibara, Toshiro, Terakawa, Yuho, Horikoshi   +11 more
openaire   +2 more sources

Getting hypervirulent Klebsiella pneumoniae on the radar screen

Current Opinion in Infectious Diseases, 2018
Purpose of review Two pathotypes of Klebsiella pneumoniae cause human infections, classical (cKp) and hypervirulent (hvKp) K. pneumoniae. The present understanding of genetic elements, the need for an accurate test to identify hvKp, the clinical implications of infection, the knowledge gap on how and why hvKp colonization ...
John A, Sellick, Thomas A, Russo
openaire   +2 more sources

Hypervirulent Klebsiella Pneumoniae Osteomyelitis in a Child

Pediatric Infectious Disease Journal
An 18-month-old boy presented with septic arthritis and osteomyelitis caused by Hypervirulent Klebsiella pneumoniae harboring cardinal virulence genes. The condition necessitated several surgical interventions, and a prolonged course of antibiotic therapy to effectively manage the severe infection and prevent complications, highlighting the challenges ...
Ryoichi Yamaki, Yusuke Isobe, Yuto Otsubo, Kohji Komori, Sohei Harada, Hiroshi Hataya, Yuho Horikoshi   +6 more
openaire   +2 more sources

Investigations of carbapenem resistant and hypervirulent Klebsiella pneumoniae

Acta Microbiologica et Immunologica Hungarica
AbstractHypervirulent Klebsiella pneumoniae is an emerging pathogen that has gained attention due to its increased ability to cause infections even in healthy individuals. The aim of this study is to investigate virulence factors in K. pneumoniae strains isolated from clinical specimens and their association with carbapenem resistance.
El Mehdi Belouad, Elmostafa Benaissa, Nadia El Mrimar, Yassine Eddair, Adil Maleb, Mostafa Elouennass   +5 more
openaire   +3 more sources

Multilocular infection caused by hypervirulent Klebsiella pneumoniae.

Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne, 2023
Hypervirulent strains of Klebsiella pneumoniae (hvKP) can cause atypical multilocular infections in otherwise healthy patients. Diagnosis of infection caused by hvKP is based mainly on clinical findings and laboratory results, including detection of virulence genes. It typically manifests as hepatic abscess with metastatic spread. Treatment is based on
T, Tyll, D, Novotný, O, Beran, E, Bartáková, J, Pudil, I, Králová Lesná, A, Rára   +6 more
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Emphysematous gastritis due to hypervirulent Klebsiella pneumoniae

The Lancet Infectious Diseases, 2022
Naomi, Saeki, Kentaro, Takei, Ken, Katsuta, Akihiko, Nakasato, Hiroaki, Baba, Kengo, Oshima, Koichi, Tokuda, Shigeki, Kushimoto, Hajime, Kanamori   +8 more
openaire   +2 more sources

Multidrug-resistant hypervirulent Klebsiella pneumoniae : an evolving superbug

Future Microbiology
Multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) combines high pathogenicity with multidrug resistance to become a new superbug. MDR-hvKP reports continue to emerge, shattering the perception that hypervirulent K. pneumoniae (hvKP) strains are antibiotic sensitive.
Yu, Zheng, Xiaojue, Zhu, Chao, Ding, Weiqiang, Chu, Xiaoxiao, Pang, Ruxia, Zhang, Jiucheng, Ma, Guoxin, Xu   +7 more
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Exploring reduced macrophage cell toxicity of hypervirulent Klebsiella pneumoniae compared to classical Klebsiella pneumoniae

Microbiological Research
Bacterial pneumoniae caused by Klebsiella pneumoniae (Kp) is a major concern due to the prevalence of multiple antibiotic-resistant strains, which limit treatment options and increase mortality rates. Patients with Kp infections often experience an uncontrolled immune response in the lungs, leading to excessive inflammation and elevated levels of ...
Sohana Akter, Mina, Gaochen, Zhu, Maryam, Fanian, Sheng, Chen, Guan, Yang   +4 more
openaire   +2 more sources