Results 11 to 20 of about 281 (158)
Drug-delivery and multifunction possibilities of hypocrellin photosensitizers [PDF]
Journal of Innovative Optical Health Sciences, 2015 Photodynamic therapy (PDT) has been a routine treatment of tumors and some microvascular diseases, but clinically available photosensitizers are still scarce.
Hong Deng, Jie Xie, Jingquan Zhao
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Contrasting regulation of live Bacillus cereus No.1 and its volatiles on Shiraia perylenequinone production [PDF]
Microbial Cell Factories, 2022 Background Fungal perylenequinones (PQs) are a class of photoactivated polyketide mycotoxins produced by plant-associated fungi. Hypocrellins, the effective anticancer photodynamic therapy (PDT) agents are main bioactive PQs isolated from a bambusicolous
Rui Xu +5 more
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FermentationHypocrellins (HYPs), naturally occurring 3,10-xylene-4,9-anthracene derivatives sourced from Shiraia bambusicola and Hypocrella bambusae, exhibit significant photobiological activities.
Xiang Zhang +10 more
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Biotechnology & Biotechnological Equipment, 2016 Hypocrellins is regarded as the new generation of potential photosensitizer in the photodynamic therapy. However, the current production of HA in large quantity is limited, whether extracted from the fruit bodies of Hypcrella bambusae and Shiraia ...
Xiao-Ye Shen +3 more
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PhysicsThe emergence of multidrug-resistant (MDR) bacteria and biofilm-associated infections has created a significant hurdle for conventional antibiotics, prompting the exploration of alternative strategies.
Pazhani Durgadevi +2 more
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Structural Diversity of Perylenequinones Is Driven by Their Redox Behavior. [PDF]
J Org Chem, 2022 Hypocrellins and hypomycins are two subclasses of fungal perylenequinones with unique structural, biological, and photochemical properties. With the growing interest in these naturally occurring photosensitizers, more studies were warranted to better ...
Al Subeh ZY +8 more
europepmc +3 more sources
Effects of 5-Azacytidine on Growth and Hypocrellin Production of Shiraia bambusicola [PDF]
Frontiers in Microbiology, 2018 Hypocrellins, fungal perylenequinones of Shiraia bambusicola are developed as important photodynamic therapy agents against cancers and viruses. Due to the limitation of the wild resources, the mycelium culture is a promising alternative for hypocrellin ...
Yan Jun Ma, Can Song Lu, Jian Wen Wang
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Effect of Structural Modification on Photodynamic Activity of Hypocrellins
Photochemistry and Photobiology, 2001 Aluminum ion complexed 5,8-di-Br-hypocrellin B is a new water-soluble perylenequinonoid derivative with enhanced absorption over hypocrellin B (HB) in the phototherapeutic window (600-900 nm). Electron paramagnetic resonance and 9,10-diphenyl-anthracene bleaching methods were used to investigate the photosensitizing activity of [AL2(5,8-di-Br-HB)Cl4]n ...
J, Ma, J, Zhao, L, Jiang
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European Food Research and Technology, 2011 Hypocrellins, including hypocrellin A and hypocrellin B, are natural red pigments isolated from a traditional Chinese medicine. The present work was designed to investigate the influence of dietary HA supplementations on the colour and emulsifying properties of egg yolk and HA distributions in tissues of laying hens.
Yujie Su +5 more
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Natural Photosensitizers in Cancer Therapy: A Chemo-Biodiversity Perspective on Light-Activated Natural Compounds. [PDF]
Chem BiodiversNatural photosensitizers, shaped by chemo‐biodiversity and evolution, offer diverse photoactive scaffolds for PDT. This review highlights their structure–activity relationships, photophysical properties, and nanotechnology‐based strategies to enhance efficacy, while addressing translational challenges and demonstrating how nature's molecular diversity ...
Baidoo I, Abrahamse H, George BP.
europepmc +2 more sources