Results 21 to 30 of about 281 (158)

Hypocrellin: A Natural Photosensitizer and Nano-Formulation for Enhanced Molecular Targeting of PDT of Melanoma. [PDF]

open access: yesWiley Interdiscip Rev Nanomed Nanobiotechnol
Nanotechnology and combination with natural photosensitizers are a prospective means of controlling cancer. Studies on photodynamic therapy (PDT) have shown that improvements in drug administration are required in order to preserve or enhance the mechanistic cell killing effects of PDT on malignant cells.
Gugu Nkosi PW, Chandran R, Abrahamse H.
europepmc   +2 more sources

Photodynamic Action of Hypocrellin A and Hypocrellin B against Cancer-A Review. [PDF]

open access: yesPharmaceuticals (Basel)
Cancer is a major global health concern, affecting nearly 20 million individuals annually, according to the International Agency for Research on Cancer (IARC). There are some unconventional and conventional treatments for cancer. Typically, they span a wide spectrum of conventional and advanced therapeutic approaches, such as photodynamic therapy (PDT).
Huang J, Law SK, Leung AWN, Xu C.
europepmc   +3 more sources

Promotion of the Hypocrellin Yield by a Co-Culture of Shiraia bambusicola (GDMCC 60438) with Arthrinium sp. AF-5 Fungus

open access: yesFermentation, 2021
Hypocrellin is a natural 3,10-xylene-4,9-anthracene derivative compound that originates from the stroma of Shiraia bambusicola (S. bambusicola) and Hypocrella bambusae with excellent photobiological activities.
Xiaoxiao Yan   +4 more
doaj   +1 more source

Structural Diversity of Perylenequinones is Driven by their Redox Behavior [PDF]

open access: yes
Hypocrellins and hypomycins are two sub-classes of fungal perylenequinones with unique phototoxic properties. Of these, more is known about hypocrellins, which were reported to have phototoxic activity against a variety of cancer cell lines and microbes;
Pearce CJ   +8 more
core   +4 more sources

Antimicrobial and Antileishmanial Activities of Hypocrellins A and B [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2004
ABSTRACT Hypocrellins A and B were evaluated for in vitro antimicrobial and antileishmanial activities. Hypocrellin A exhibited promising activity against Candida albicans and moderate activity against Staphylococcus aureus , methicillin-resistant S. aureus ,
Guoyi, Ma   +7 more
openaire   +2 more sources

The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production

open access: yesMicrobial Cell Factories, 2021
Background Adenosine 5′-triphosphate (ATP) plays both a central role as an intracellular energy source, and a crucial extracellular signaling role in diverse physiological processes of animals and plants.
Xin Ping Li   +3 more
doaj   +1 more source

Efficient agrobacterium-mediated transformation of Shiraia bambusicola and activation of a specific transcription factor for hypocrellin production

open access: yesBiotechnology & Biotechnological Equipment, 2019
Shiraia bambusicola, as a well-known medicinal and edible macro-fungus, is generally located on the branches of bamboo and plays an important role in herbal treatment.
Tong Li, Cheng-Lin Hou, Xiao-Ye Shen
doaj   +1 more source

Enhanced hypocrellin production via coexpression of alpha-amylase and hemoglobin genes in Shiraia bambusicola

open access: yesAMB Express, 2018
Shiraia bambusicola is an important and valuable macrofungus and hypocrellins are its main secondary metabolites which have been widely applied in many medical fields.
Ruijie Gao   +4 more
doaj   +1 more source

Inducing perylenequinone production from a bambusicolous fungus Shiraia sp. S9 through co-culture with a fruiting body-associated bacterium Pseudomonas fulva SB1

open access: yesMicrobial Cell Factories, 2019
Background Fungal perylenequinonoid (PQ) pigments from Shiraia fruiting body have been well known as excellent photosensitizers for medical and agricultural uses. The fruiting bodies are colonized by a diverse bacterial community of unknown function.
Yan Jun Ma, Li Ping Zheng, Jian Wen Wang
doaj   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

open access: yesPhotochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi   +2 more
wiley   +1 more source

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