Results 31 to 40 of about 281 (158)
High Efficiency Hypocrellin Production by a Novel Mutant Isolated from Shiraia bambusicola [PDF]
, 2019 The fungus Shiraia bambusicola GZ19M1 is biotechnologically important due to its ability to biosynthesis the pigment hypocrellins. Results showed that ethyl methane sulfonate (EMS) was effective mutagenic agent for strain and potentially produced large ...
DU,Wen, WANG,Baogui
core +1 more source
Advanced Science, Volume 13, Issue 23, 23 April 2026.Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang +14 more
wiley +1 more source
Hypocrellin B, a perylenequinonoid pigment, and its complexes with lanthanide ions: optical characterization and enhancements in its photodynamic properties [PDF]
, 2009 Hypocrellins, perylenequinonoid pigments isolated from Hypocrella bambusae, are known photodynamic agents. They exhibit several advantages over the other photosensitizers, such as ready preparation, easy purification, low aggregation tendency, high ...
Coronato, Courrol Lilia [UNIFESP] +5 more
core +1 more source
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Perylenequinone Natural Products: Total Synthesis of Hypocrellin A [PDF]
The Journal of Organic Chemistry, 2009 An efficient and stereoselective total synthesis of the perylenequinone natural product hypocrellin A (1) is described. The key features include a potentially biomimetic 1,8-diketone aldol cyclization to set the centrochiral C7,C7'-stereochemistry, bis(trifluoroacetoxy)iodobenzene mediated oxygenation, a palladium-catalyzed decarboxylation, and an ...
Erin M, O'Brien +4 more
openaire +2 more sources
Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles
Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane +1 more
wiley +1 more source
Green‐Synthesised Nanoconjugates: Advancing Targeted Photodynamic Therapy for Lung Cancer
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.ABSTRACT Lung cancer is a type of cancer that develops around the airways or lungs and continues to be the leading cause of cancer‐related deaths worldwide. This has necessitated the need for innovative therapeutic strategies to overcome the limits of existing therapies such as surgery, chemotherapy and radiotherapy.
Njabulo Henry Sibanda +2 more
wiley +1 more source
Emerging applications of rare‐earth fluoride nanocrystals in medicine and biotechnologies
Responsive Materials, Volume 3, Issue 4, November 2025.Rare‐earth fluoride nanocrystals (REFNCs) exhibit high responsivity and can be used as multi‐modal agents in medicine and theranostics. This review summarizes recent advances in REFNCs, covering their synthesis, structures, luminescent properties, and applications in multi‐modal imaging and photodynamic therapy, highlighting their theranostic potential
Alain Tressaud +3 more
wiley +1 more source
Development and Application of Organic Sonosensitizers in Cancer Therapy
Aggregate, Volume 6, Issue 6, June 2025.This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding +5 more
wiley +1 more source
Advanced NanoBiomed Research, Volume 5, Issue 6, June 2025.Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska +2 more
wiley +1 more source