Results 141 to 150 of about 29,698,539 (199)

Editorial: Reviews in sleep: 2024. [PDF]

Front Sleep
Brown RE, Poyares DLR, Sheldon S, Basheer R.   +3 more
europepmc   +1 more source

Sleep-related eating disorder after dose escalation of sodium oxybate in narcolepsy type 1. [PDF]

J Taibah Univ Med Sci
Al Mazyad RA, Alhajaji R, Dhafar HO, BaHammam AS.   +3 more
europepmc   +1 more source

Neurobiology of negative reinforcement as a driving force in alcohol addiction. [PDF]

Neuron
Vendruscolo LF, Koob GF.
europepmc   +1 more source

Signalling mechanisms used by the orexin-1 receptor [PDF]

Peltonen, Hanna
core  

Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury

Neurology, 2005
Hypocretin-1 is involved in the regulation of the sleep-wake cycle. The authors prospectively assessed CSF hypocretin-1 levels in 44 consecutive patients with acute traumatic brain injury (TBI). Compared with controls, hypocretin-1 levels were abnormally lower in 95% of patients with moderate to severe TBI and in 97% of patients with posttraumatic ...
Baumann, C R, Stocker, R, Imhof, H G, Trentz, O, Hersberger, M, Mignot, E, Bassetti, C L   +6 more
openaire   +5 more sources

An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

Neuroscience, 2015
The hypocretin/orexin system regulates, among other things, sleep and energy homeostasis. The system is likely regulated by both homeostatic and circadian mechanisms. Little is known about local differences in the regulation of hypocretin activity.
Justinussen, J L, Holm, A, Kornum, B R
openaire   +4 more sources

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Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration

Neuroscience, 2003
Hypocretin/orexin modulates sleep-wake state via actions across multiple terminal fields. Within waking, hypocretin may also participate in high-arousal processes, including those associated with stress. The current studies examined the extent to which alterations in neuronal activity, as measured by Fos immunoreactivity, occur within both hypocretin ...
Rita Valentino, Rodrigo España, C W Berridge   +2 more
exaly   +3 more sources

Extracellular GABA in the medial hypothalamus is increased following hypocretin‐1 administration

Acta Physiologica Scandinavica, 2004
AbstractAim: Hypocretin 1 is an hypothalamic neuropeptide that induces an increase in food intake when administered into the cerebral lateral ventricle. As it is well known that the medial hypothalamus (MH) is involved in the feeding behaviour also through GABAergic circuits, the aim of this experiment was to investigate the effect of an hypocretin 1 ...
VIGGIANO, Alessandro, MONDA, Marcellino, Viggiano A, Fuccio F, De Luca B.   +4 more
openaire   +4 more sources

Narcolepsy with intermediate cerebrospinal level of hypocretin-1

Sleep, 2021
AbstractStudy ObjectivesTo describe the phenotype of narcolepsy with intermediate cerebrospinal fluid hypocretin-1 levels (CSF hcrt-1).MethodsFrom 1600 consecutive patients with narcolepsy from Bologna and Montpellier sleep centers, we selected patients with intermediate CSF hcrt-1 levels (110–200 pg/mL).
Emanuela Postiglione, Lucie Barateau, Fabio Pizza, Régis Lopez, Elena Antelmi, Anna-Laura Rassu, Stefano Vandi, Sofiene Chenini, Emmanuel Mignot, Yves Dauvilliers, Giuseppe Plazzi   +10 more
openaire   +4 more sources