Serum hypocretin, neurofilament heavy chain, and interleukin-1β as combined predictors of sleep disorders following acute ischemic stroke. [PDF]
Wang C, Mao Y, Wang S, Liu L, Yao G.
europepmc +1 more source
Orexinergic responses to environmental stressors in the zebrafish gut. [PDF]
Sang Y, Dixon CT, Graves CL.
europepmc +1 more source
High-resolution sleep fragmentation assessment in narcolepsy type 1 and their non-narcoleptic siblings: a 5-s mini-epoch study. [PDF]
Follin LF +11 more
europepmc +1 more source
G protein activation and acetylcholine release stimulated by hypocretin in the rat pons.
Multiple brain stem nuclei, including locus coeruleus (LC), dorsal raphe nucleus (DR), and the oral (PnO) and caudal (PnC) part of the pontine reticular formation participate in the modulation of arousal states.
Bernard, Rene
core
Human narcolepsy is linked to degeneration of both locus coeruleus and hypocretin neurons. [PDF]
Thannickal TC +3 more
europepmc +1 more source
Editorial: Neuromodulation of mood and eating behavior. [PDF]
de Gortari P +2 more
europepmc +1 more source
Narcolepsy: Pathophysiology, Diagnosis, Management, and Future Directions, a Narrative Review. [PDF]
Hastings NE +12 more
europepmc +1 more source
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
Hypocretin has been identified as a regulator of metabolic and endocrine systems. Several brain regions involved in the central regulation of autonomic and endocrine processes or attention are targets of extensive hypocretin projections.
Peyron, C +6 more
core
Hypocretin receptor 1 blockade early in abstinence prevents incubation of cocaine seeking and normalizes dopamine transmission. [PDF]
Clark PJ +6 more
europepmc +1 more source
The hypocretin/orexin system mediates the extinction of fear memories
Anxiety disorders are often associated with an inability to extinguish learned fear responses. The hypocretin/orexin system is involved in the regulation of emotional states and could also participate in the consolidation and extinction of aversive ...
Saravia, Rocío +5 more
core

