Results 131 to 140 of about 8,767 (247)
The Hypocretin/Orexin System [PDF]
Journal of the Royal Society of Medicine, 2002 Ebrahim, I O +4 more
openaire +2 more sources
Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination
, 2011 Recent studies recognize that Hypocretin system (also known as Orexin) plays a critical role in sleep/wake disorders and feeding behaviors. However, little is known about the regulation of the Hypocretin system.
Zhan, Shuqin +17 more
core +1 more source
Overview of orexin/hypocretin system
A series of recent studies has established the orexin/hypocretin system as a critical regulator of sleep/wake states. Its deficiency results in the sleep disorder narcolepsy in humans, dogs, and rodents.
Sakurai, Takeshi, Mieda, Michihiro
core
Narcolepsy type 1 and hypocretin neurons
Der er konsensus om, at narkolepsi type 1 skyldes et autoimmunt tab af hypokretinproducerende neuroner i hypothalamus.Ny forskning foreslår, at epigenetisk silencing kan være årsag til narkolepsi.Epigenetisk silencing kan foranledige nye ...
Kornum, Birgitte Rahbek +2 more
core +1 more source
Anti-Ma2 Encephalitis as a Treatable Cause of Narcolepsy Type 1: A Case Report. [PDF]
Am J Case RepWang M, Zhang N, Bian Z, Li Y, Wang S.
europepmc +1 more source
Hypocretin-1 and GABA in the Pontine Reticular Formation Interact to Promote Wakefulness. [PDF]
Hypocretin-1 and hypocretin-2 are wake-promoting neuropeptides that are exclusively synthesized in the lateral hypothalamus. Hypocretin deficiency underlies the sleep disorder narcolepsy, which is characterized by excessive daytime sleepiness and ...
Brevig, Holly N.
core
Orexins, Psychosis, and Antipsychotics: A Systematic Review of Studies of Orexin Levels and the Effects of Dual Orexin Receptor Antagonists (DORAs). [PDF]
Brain SciMargoni S +11 more
europepmc +1 more source