Fear and Foxes: An Educational Primer for Use with "Anterior Pituitary Transcriptome Suggests Differences in ACTH Release in Tame and Aggressive Foxes". [PDF]
The way genes contribute to behavior is complicated. Although there are some single genes with large contributions, most behavioral differences are due to small effects from many interacting genes.
Simpson, Julie H
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Disorders of sleep and wakefulness occur in the majority of individuals who have experienced traumatic brain injury (TBI), with increased sleep need and excessive daytime sleepiness often reported.
Hannah E. Thomasy +4 more
doaj +1 more source
Brazilian guidelines for the diagnosis of narcolepsy [PDF]
Este artigo relata as conclusões da reunião de consenso com médicos especialistas sobre diagnóstico de narcolepsia baseada na revisão dos artigos sobre narcolepsia listados no Medline entre 1980 e 2010.
ALVES, Rosana Cardoso +28 more
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Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far
Emerging findings suggest the existence of a cross-talk between hypocretinergic and endocannabinoid systems. Although few studies have examined this relationship, the apparent overlap observed in the neuroanatomical distribution of both systems as well ...
África eFlores +2 more
doaj +1 more source
Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity [PDF]
Two promising lead structures of small molecular orexin receptor agonist have been reported, but without detailed analyses of the pharmacological properties.
af Gennas, Gustav Boije +5 more
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Estudo dos linfócitos T CD4, CD8 e B em pacientes com narcolepsia [PDF]
Narcolepsy is characterized by excessive daytime sleep and cataplexy. Little is known about the possible difference in pathophysiology between patients with or without cataplexy.
Alves, Gabriela Rodrigues +6 more
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Hypocretin underlies the evolution of sleep loss in the Mexican cavefish [PDF]
The duration of sleep varies dramatically between species, yet little is known about the genetic basis or evolutionary factors driving this variation in behavior. The Mexican cavefish, Astyanax mexicanus, exists as surface populations that inhabit rivers,
Duboue, Erik R. +5 more
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Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli +291 more
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Abnormal activity in hypothalamus and amygdala during humour processing in human narcolepsy with cataplexy [PDF]
Narcolepsy with cataplexy (NC) is a complex sleep-wake disorder, which was recently found to be associated with a reduction or loss of hypocretin (HCRT, also called orexin). HCRT is a hypothalamic peptide implicated in the regulation of sleep/wake, motor
Bassetti, C L. +6 more
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Parkinsonism with excessive daytime sleepiness: A narcolepsy-like disorder? [PDF]
: Background : Parkinsonian patients with excessive daytime sleepiness (EDS), hallucinations, REM sleep behavior disorder (RBD), short mean sleep latencies, and sleep-onset REM periods (SOREMP) on multiple sleep latency tests (MSLT) have been reported ...
Bassetti, Claudio +4 more
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