Results 171 to 180 of about 96,734 (308)

Prevalence and Burden of Fatigue Across Disorders of Gut–Brain Interaction: Results From the Rome Foundation Global Epidemiology Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...
Fleur Veldman   +7 more
wiley   +1 more source

Shame as a mediator of the association of childhood emotional abuse with aversive cognitive perseveration in adults

open access: yesBritish Journal of Psychology, EarlyView.
Abstract Childhood emotional abuse (CEA) has been linked to response‐focused emotion regulation in adulthood. However, the underlying mechanisms remain unexplored. This pre‐registered study examined whether shame mediates the association between CEA history and aversive cognitive perseveration (ACP), including brooding rumination, experiential ...
Mohammadali Amini‐Tehrani   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non‐Functioning Pituitary Adenoma

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius   +6 more
wiley   +1 more source

A network of basolateral amygdala projection neurons contributes to stress-induced activation of the hypothalamic-pituitary-adrenal axis. [PDF]

open access: yesSci Adv
Aukema RJ   +9 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth   +7 more
wiley   +1 more source

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