Results 191 to 200 of about 130,466 (307)

Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model. [PDF]

Brain Sci
Samdavid Thanapaul RJR, Krishnan JKS, Govindarajulu MY, Pundkar CY, Phuyal G, Long JB, Arun P.   +6 more
europepmc   +1 more source

Management of adrenal insufficiency risk after long-term systemic glucocorticoid therapy in Duchenne muscular dystrophy: Clinical practice recommendations [PDF]

, 2019
Bowden, Sasigarn A, Connolly, Anne M, Kinnett, Kathi, Zeitler, Philip S   +3 more
core   +1 more source

Sleep Deprivation in Mice: Looking Beyond the Slow Wave Rebound

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep is a fundamental process supporting the dynamic regulation of neural function. Emerging methods have proposed that the aperiodic components of brain signals (such as the spectral slope, spectral intercept, and spectral knee), in addition to entropy‐based measures, offer robust empirical markers of neural states.
Tárek Zoltán Magyar, Orsolya Szalárdy, Róbert Bódizs   +2 more
wiley   +1 more source

The Interplay Between Emotion Dysregulation and Repetitive Thoughts in Insomnia Disorder: The Impact of Worry, Rumination and REM Sleep Instability

Journal of Sleep Research, EarlyView.
ABSTRACT While previous research has identified emotional dysregulation and repetitive thinking as contributors to insomnia, the interplay between these factors remains unclear. Building upon data previously collected in our laboratory, this exploratory study extends prior findings by examining the mediating role of rumination, worry and rapid eye ...
Samantha Mombelli, Elisabetta Fasiello, Maria Caterina Di Perri, Francesca Casoni, Marco Zucconi, Luigi Ferini‐Strambi, Andrea Galbiati   +6 more
wiley   +1 more source

Hypothalamic-Pituitary-Adrenal Axis Dysfunction in People With Cancer: A Systematic Review. [PDF]

Cancer Med
Kanter NG, Cohen-Woods S, Balfour DA, Burt MG, Waterman AL, Koczwara B.   +5 more
europepmc   +1 more source

Increased p‐Tau181 Levels After Overnight Wakefulness Are Associated With Neuroticism in Young Women

Journal of Sleep Research, EarlyView.
Overnight wakefulness, mimicking night shift conditions, impaired morning vigilance in healthy, reproductive‐aged women, regardless of estradiol or neuroticism. However, the overnight wakefulness‐related rise in the Alzheimer's disease blood biomarker p‐Tau181 was greater in women with higher neuroticism, suggesting that neurobiological vulnerability ...
Diana A. Nôga, Elisa M. S. Meth, Abdullah Almajni, Viviana Rossi, Camilla Zetterlund, Samira F. M. Noory, Michaela Danek, Asma Al‐Grety, André P. Pacheco, Meina Wu, Mia Phillipson, Henrik Zetterberg, Kim Kultima, Pei Xue, Christian Benedict   +14 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Once‐Daily and Proactive Twice‐Weekly Roflumilast Cream 0.05% for Mild‐to‐Moderate Atopic Dermatitis in Children Aged 2–5 Years From a 52‐Week, Phase 3 Trial (INTEGUMENT‐OLE)

Pediatric Dermatology, EarlyView.
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield, Mercedes E. Gonzalez, Mark Boguniewicz, Tracy Funk, Adelaide A. Hebert, Vimal H. Prajapati, Chesahna Kindred, Rocco Serrao, Lisa Swanson, David Krupa, Scott Snyder, Melissa S. Seal, Diane Hanna, Patrick Burnett, David R. Berk   +14 more
wiley   +1 more source

Severe hypoglycaemia secondary to chronic opioid-induced hypothalamic-pituitary-adrenal axis suppression: an under-recognised phenomenon. [PDF]

Med J Aust
Do M, Hayes AG, Brzozowska MM.
europepmc   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Heat stress affects dairy cow performance via oxidative stress, hypothalamic-pituitary-adrenal axis, gut microbiota, and multi-dimensional mitigation. [PDF]

Front Vet Sci
Zhang Q, Yang L, Li Y, Gu P, Si R, Zhu L, Zhang W.   +6 more
europepmc   +1 more source