Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis
In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes, the hypothalamic–pituitary–thyroid and the hypothalamic–pituitary–adrenal/interrenal axes, are central players in orchestrating
Bidisha Paul +4 more
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Altered hypothalamic protein expression in a rat model of Huntington's disease. [PDF]
Huntington's disease (HD) is a neurodegenerative disorder, which is characterized by progressive motor impairment and cognitive alterations. Changes in energy metabolism, neuroendocrine function, body weight, euglycemia, appetite function, and circadian ...
Wei-na Cong +8 more
doaj +1 more source
Soluble Fermentable Dietary Fibre (Pectin) Decreases Caloric Intake, Adiposity and Lipidaemia in High-Fat Diet-Induced Obese Rats [PDF]
Funding: This work was funded by the Scottish Government Rural and Environment Science and Analytical Services Division. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Adam, Clare L +3 more
core +6 more sources
Geoffrey Wingfield Harris (1913-1971), padre de la neuroendocrinología
Background: The purpose of this narrative review is to highlight the work of Geoffrey W. Harris on the relationship between the hypothalamus and the pituitary gland, particularly the hypothalamic-pituitary-ovarian axis.
Alfredo Jacome-Roca
doaj +1 more source
Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat [PDF]
Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR ...
Jahn, Graciela Alma +4 more
core +1 more source
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
Hypothalamic hormones a.k.a. hypothalamic releasing factors [PDF]
Originally searched for and eventually isolated as factors of hypothalamic origin controlling anterior pituitary secretions, these hypophysiotropic peptides are now a chapter of physiology and medical endocrinology of their own. Defying the concept of ‘neuropeptides’ they and their receptors are now known to be ubiquitous and to have subtle as well as ...
openaire +2 more sources
Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E. +6 more
core +1 more source
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis. [PDF]
In several species caloric restriction (CR) extends life span. In this paper we integrate data from studies on CR and other sources to articulate the hypothalamic deregulation hypothesis by which estrogen receptor-alpha (ER-α) signaling in the ...
Barakat, Rita +6 more
core +1 more source
Hypothalamic AMP-Activated Protein Kinase as a Whole-Body Energy Sensor and Regulator [PDF]
5´-Adenosine monophosphate (AMP)-activated protein kinase (AMPK), a cellular energy sensor, is an essential enzyme that helps cells maintain stable energy levels during metabolic stress. The hypothalamus is pivotal in regulating energy balance within the
Se Hee Min +4 more
doaj +1 more source

