Antioxidants, 2023 Lesch–Nyhan syndrome (LN) is an is an X-linked recessive inborn error of metabolism that arises from a deficiency of purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT).
Julie A. Reisz +5 more
doaj +1 more source
Atrial Natriuretic Peptide, a Regulator of Nuclear Factor-κB Activation in Vivo [PDF]
, 2007 Natriuretic peptides (NPs) comprise a family of vasoactive hormones that play important roles in the regulation of cardiovascular and renal homeostasis.
Keller, Melanie +6 more
core +1 more source
The Secreted Acid Phosphatase Domain-Containing GRA44 from Toxoplasma gondii Is Required for c-Myc Induction in Infected Cells. [PDF]
, 2020 During host cell invasion, the eukaryotic pathogen Toxoplasma gondii forms a parasitophorous vacuole to safely reside within the cell, while it is partitioned from host cell defense mechanisms.
Arrizabalaga, Gustavo +2 more
core +1 more source
In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis. [PDF]
, 2016 UnlabelledToxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into ...
Bell, Hannah N +7 more
core +2 more sources
Data in support of the mutagenic potential of the isoflavone irilone in cultured V79 cells
Data in Brief, 2015 The isoflavone irilone is found in human plasma after ingestion of red clover-based dietary supplements, but information allowing safety assessment is rare.
Anne Scheffler +3 more
doaj +1 more source
Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy [PDF]
, 2013 Nucleosides have a wide range of physiological and pathophysiological roles in the human brain as modulators of a variety of neural functions. For example, adenosine, inosine, guanosine, and uridine participate in the mechanisms underlying memory ...
Dobolyi, Árpád, Kovács, Zsolt
core +1 more source
AIMS Neuroscience, 2022 A heterozygous Arg393His point mutation at the reactive site of antithrombin (AT) gene causing thrombosis in a Vietnamese patient is reported and named as Arg393His in AT-Hanoi.
Khue Vu Nguyen
doaj +1 more source
A Rapid and Specific Method for Separation of Bound and Free Antigen in Radioimmunoassay Systems [PDF]
, 1979 Peer ...
Müller, O. A. +3 more
core +2 more sources
Uric acid, an important screening tool to detect inborn errors of metabolism: a case series
BMC Research Notes, 2017 Background Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism.
Eresha Jasinge +10 more
doaj +1 more source
CodY, a pleiotropic regulator, influences multicellular behaviour and efficient production of virulence factors in Bacillus cereus [PDF]
, 2012 In response to nutrient limitation in the environment, the global transcriptional regulator CodY modulates various pathways in low G+C Gram-positive bacteria.
Basset, Coraline +6 more
core +3 more sources