Results 201 to 210 of about 649,237 (386)

Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription. [PDF]

J Biol Chem, 2023
Downes N, Niskanen H, Tomas Bosch V, Taipale M, Godiwala M, Väänänen MA, Turunen TA, Aavik E, Laham-Karam N, Ylä-Herttuala S, Kaikkonen MU.   +10 more
europepmc   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

Expression of hypoxia-inducible factor 1: mechanisms and consequences

, 2000
Gregg L. Semenza
openalex   +1 more source

Retracted: Effects of Hypoxia-Inducible Factor 1 (HIF-1) Signaling Pathway on Acute Ischemic Stroke. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Red Blood Cell Membrane‐Camouflaged Red Phosphorus‐Modified C3N4 for Enhanced Tumoral Photodynamic Therapy

Advanced Materials Interfaces, EarlyView.
Photodynamic therapy (PDT) faces clinical challenges due to poor tumor targeting and systemic toxicity. Herein, a biomimetic C3N4‐RP@RBCm nanoplatform is developed via erythrocyte membrane encapsulation, enabling CD47‐mediated immune evasion and EPR‐driven tumor accumulation.
Jiaxiu Liu, Jingying Chen, Tianyang Li, Pingping Meng, Xitong Lin, Yuting Zhai, Yukun Zhu, Daohao Li, Dongjiang Yang, Shuchao Zhang   +9 more
wiley   +1 more source

Mechanisms of Breast Cancer Stem Cell Specification and Self-Renewal Mediated by Hypoxia-Inducible Factor 1. [PDF]

Stem Cells Transl Med, 2023
Semenza GL.
europepmc   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten   +7 more
wiley   +1 more source

Hypothetical role of hypoxia-inducible factor-1 in adaptations to microgravity

Revista Cubana de Investigaciones Biomédicas, 2019
Maintaining health in microgravity and overcoming environmental hazards such as cosmic radiation are essential for long-term space flight. Recent studies have focused on the involvement of hypoxia-inducible factor (HIF)-1 in altered gravity using cell ...
Yang Sook Chun, Alan R. Hargens
doaj  

Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

Molecular and Cellular Biology, 2005
R. Raval, K. W. Lau, Maxine G. B. Tran, H. Sowter, S. Mandriota, Ji-Liang Li, C. Pugh, P. Maxwell, A. Harris, P. Ratcliffe   +9 more
semanticscholar   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

Advanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı, Songjin Oh, Eunae Kim, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man Jeong Paik, Hangun Kim   +7 more
wiley   +1 more source