Results 211 to 220 of about 136,903 (266)

Atypical chemokine receptor 2 expression is directly regulated by hypoxia inducible factor-1 alpha in cancer cells under hypoxia. [PDF]

Sci Rep
Benoit A, Lequeux A, Harter P, Berchem G, Janji B.   +4 more
europepmc   +1 more source

Multiple roles for hypoxia inducible factor 1-alpha in airway epithelial cells during mucormycosis. [PDF]

Nat Commun
Kavaliauskas P, Gu Y, Hasin N, Graf KT, Alqarihi A, Shetty AC, McCracken C, Walsh TJ, Ibrahim AS, Bruno VM.   +9 more
europepmc   +1 more source

Hypoxia-inducible factor-1 alpha and nuclear factor erythroid 2-related factor 2 as biomarkers of renal scarring in children with congenital anomalies of the kidney and urinary tract: a prospective case-control study. [PDF]

BMC Nephrol
Gençler A, Çelik H, Padalı F, Demir A, Kafadar S.   +4 more
europepmc   +1 more source

The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure. [PDF]

Int J Mol Sci
Mücke MM, El Bali N, Schwarzkopf KM, Uschner FE, Kraus N, Eberle L, Mücke VT, Bein J, Beyer S, Wild PJ, Schierwagen R, Klein S, Zeuzem S, Welsch C, Trebicka J, Brieger A.   +15 more
europepmc   +1 more source

Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis

Lockwood C, Daley KK, O’Neil JD, Heighes KJ, Clayton SA, Clark AR.   +5 more
europepmc   +1 more source

Statement of Retraction: Knockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes. [PDF]

Bioengineered
europepmc   +1 more source

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Hypoxia-Inducible Factor-1 (HIF-1)

Molecular Pharmacology, 2006
Adaptation to low oxygen tension (hypoxia) in cells and tissues leads to the transcriptional induction of a series of genes that participate in angiogenesis, iron metabolism, glucose metabolism, and cell proliferation/survival. The primary factor mediating this response is the hypoxia-inducible factor-1 (HIF-1), an oxygen-sensitive transcriptional ...
Qingdong, Ke, Max, Costa
openaire   +2 more sources

Hypoxia Induces Transcription Factor ETS-1 via the Activity of Hypoxia-Inducible Factor-1

Biochemical and Biophysical Research Communications, 2001
ETS-1 plays an important role in angiogenesis and cancer invasion, and hypoxia is a common feature in these phenomena. We examined whether hypoxia influenced ETS-1 expression. Hypoxia induced ETS-1 in a human bladder cancer cell line, T24, and promoter analysis revealed that the deletion of -424 to -279 bp from the human ETS-1 promoter decreased the ...
M, Oikawa, M, Abe, H, Kurosawa, W, Hida, K, Shirato, Y, Sato   +5 more
openaire   +2 more sources

Hypoxia Induced Infertility in Males: Role of Transcription Factor Hypoxia Inducible Factor -1 Alpha

Pakistan Journal of Medical and Health Sciences, 2022
Aim: To assess concentrations of HIF-1 α and correlation between HIF-1 α in healthy and sub fertile males’ population in our study. Methodology: In this study we investigated the concentrations of Hypoxia Inducible Factor 1-α (pg/mL) in the seminal plasma of healthy fertile males and sub fertile males using Enzyme-Linked ImmunoSorbent Assay (ELISA ...
Aasma Zaidi, Zaheer Iqbal Sheikh, Afsheen Akbar, Shaheena Naz, Shazia Ramzan, Faiza Habib   +5 more
openaire   +1 more source

Hypoxia-inducible factor 1 in autoimmune diseases

Cellular Immunology, 2016
Autoimmune disorders are a complicated and varied group of diseases arising from inappropriate immune responses. Recent studies have demonstrated that ongoing inflammatory and immune responses are associated with increased oxygen consumption, a process resulting in localized tissue hypoxia within inflammatory lesions ("inflammatory hypoxia"), in which ...
Wei, Deng, Xuebing, Feng, Xia, Li, Dandan, Wang, Lingyun, Sun   +4 more
openaire   +2 more sources