Pharmacokinetics during therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy: a literature review [PDF]
Background Neonatal hypoxic ischaemic encephalopathy due to perinatal asphyxia, can result in severe neurodevelopmental disability or mortality. Hypothermia is at present the only proven neuroprotective intervention.
Karel Allegaert +3 more
doaj +3 more sources
Cooling for newborns with hypoxic ischaemic encephalopathy [PDF]
Newborn animal studies and pilot studies in humans suggest that mild hypothermia following peripartum hypoxia-ischaemia in newborn infants may reduce neurological sequelae without adverse effects.To determine the effect of therapeutic hypothermia in encephalopathic asphyxiated newborn infants on mortality, long-term neurodevelopmental disability and ...
Susan E, Jacobs +5 more
openaire +3 more sources
Early blood glucose profile and neurodevelopmental outcome at two years in neonatal hypoxic-ischaemic encephalopathy [PDF]
Background To examine the blood glucose profile and the relationship between blood glucose levels and neurodevelopmental outcome in term infants with hypoxic-ischaemic encephalopathy.
Dempsey Eugene M +4 more
doaj +2 more sources
Moderate therapeutic hypothermia is a promising technique for cerebral damage management aimed at the reduction of mortality and disability after hypoxic ischaemic encephalopathy.
A. A. Zadvornov +2 more
doaj +3 more sources
Therapeutic hypothermia increases the risk of cardiac arrhythmia for perinatal hypoxic ischaemic encephalopathy: A meta-analysis. [PDF]
OBJECTIVE:To determine whether therapeutic hypothermia after hypoxic ischaemic encephalopathy (HIE) in neonates increases the risk of cardiac arrhythmia during intervention. DESIGN:A meta-analysis was conducted using a fixed-effect model.
Wei Zhang +7 more
doaj +2 more sources
Motor, cognitive and behavioural outcomes after neonatal hypoxic-ischaemic encephalopathy
Introduction: The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift of severe pathology towards mild motor disorders and emotional problems ...
María Montesclaros Hortigüela +4 more
doaj +2 more sources
Therapeutic hypothermia remains the only proven treatment to improve mortality and morbidity in neonates with hypoxic–ischaemic encephalopathy (HIE). Preclinical models have demonstrated erythropoietin as a potential adjuvant therapy in neonatal HIE due ...
Chung, Lorraine Marie +3 more
core +2 more sources
Hypoxic-ischaemic encephalopathy code: A systematic review for resource-limited settings
It is estimated that 96% of infants with hypoxic-ischaemic encephalopathy (HIE) are born in resource-limited settings with no capacity to provide the standard of care that has been established for nearly 15 years in high-resource countries, which ...
Alfredo Garcia-Alix +3 more
doaj +2 more sources
Early neurodevelopmental outcome in newborns with mild hypoxic‐ischaemic encephalopathy
Aim To describe the natural history of newborn children with mild hypoxic‐ischaemic encephalopathy in the first year of life. Method This was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian Society ...
Domenico M. Romeo +16 more
wiley +2 more sources
Motor performance and higher associative cortical networks in adolescents with neonatal hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia. [PDF]
To investigate the interaction between specialized motor networks and higher associative brain networks for motor performance in adolescents exposed to neonatal hypoxic‐ischaemic encephalopathy (HIE).
Håkansson G +5 more
europepmc +2 more sources

