Results 91 to 100 of about 20,996 (180)

Impact of genetically improved fish species and technology on selected hatchery and fish production in Bangladesh

open access: yesInternational Journal of Agricultural Research, Innovation and Technology, 2017
The study was carried out in IAPP commanding areas from July to September 2015. A total of 8 hatchery and 240 farmers were selected for this study from Rangpur and Barisal region.
MS Islam
doaj   +1 more source

Bistable dynamics underlying excitability of ion homeostasis in neuron models

open access: yes, 2014
When neurons fire action potentials, dissipation of free energy is usually not directly considered, because the change in free energy is often negligible compared to the immense reservoir stored in neural transmembrane ion gradients and the long-term ...
Dahlem, Markus A.   +2 more
core   +2 more sources

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

open access: yesJournal of Diabetes Research, 2016
The hormone islet amyloid polypeptide (IAPP, or amylin) plays a role in glucose homeostasis but aggregates to form islet amyloid in type-2 diabetes. Islet amyloid formation contributes to β-cell dysfunction and death in the disease and to the failure of ...
Rehana Akter   +10 more
doaj   +1 more source

Molecular Lysine Tweezers Counteract Aberrant Protein Aggregation. [PDF]

open access: yes, 2019
Molecular tweezers (MTs) are supramolecular host molecules equipped with two aromatic pincers linked together by a spacer (Gakh, 2018). They are endowed with fascinating properties originating from their ability to hold guests between their aromatic ...
Bitan, Gal   +4 more
core  

Determination of Spectral Focusing Features of a Metamaterial Slab [PDF]

open access: yes, 2009
The realization of flat superlenses is a major application area of metamaterials. A slab of double negative (DNG) material is capable of imaging with a resolution below the diffraction limit.
Culhaoglu, Ali Eren   +2 more
core  

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity. [PDF]

open access: yes, 2017
hIAPP fibrils are associated with Type-II Diabetes, but the link of hIAPP structure to islet cell death remains elusive. Here we observe that hIAPP fibrils are cytotoxic to cultured pancreatic β-cells, leading us to determine the structure and ...
Cascio, Duilio   +15 more
core   +1 more source

Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus

open access: yesClinical Interventions in Aging, 2015
Hye Rin Jeong, Seong Soo A AnDepartment of Bionano Technology, Gachon Medical Research Institute, Gachon University, Gyeonggi-do, Republic of KoreaAbstract: Human islet amyloid polypeptide (h-IAPP) is a peptide hormone that is synthesized and cosecreted ...
Jeong HR, An SSA
doaj  

Bistable organic electrochemical transistors: enthalpy vs. entropy

open access: yesNature Communications
Organic electrochemical transistors (OECTs) underpin a range of emerging technologies, from bioelectronics to neuromorphic computing, owing to their unique coupling of electronic and ionic charge carriers.
Lukas M. Bongartz   +8 more
doaj   +1 more source

An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells

open access: yesMolecular Metabolism
Objective: Human embryonic stem cell (hESC; SC)-derived pancreatic β cells can be used to study diabetes pathologies and develop cell replacement therapies.
Carmen L. Bayly   +6 more
doaj   +1 more source

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