iciHHV-6 in a Patient With Multisystem Inflammatory Syndrome in Children [PDF]
Pediatrics, 2021 Multisystem inflammatory syndrome in children (MIS-C) is a serious, sometimes life-threatening late complication of coronavirus disease 2019 (COVID-19) with multiorgan involvement and evidence of immune activation. The pathogenesis of MIS-C is not known, nor is the pathogenesis of the severe organ damage that is the hallmark of MIS-C. Human herpesvirus
Lisa, Biswas +6 more
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Inherited Chromosomally Integrated Human Herpesvirus 6: Laboratory and Clinical Features [PDF]
Microorganisms, 2023 Inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) is a condition in which the complete HHV-6 genome is integrated into the chromosomes of the host germ cell and is vertically transmitted.
Liliana Gabrielli +10 more
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Investigation of Inherited Chromosomally Integrated Human Herpesvirus-6A+ and -6B+ in a Patient with Ulipristal Acetate-Induced Fulminant Hepatic Failure [PDF]
Viruses, 2021 Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo +6 more
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Transmission dynamics of human herpesvirus 6A, 6B and 7 from whole genome sequences of families [PDF]
Virology Journal, 2022 While hundreds of thousands of human whole genome sequences (WGS) have been collected in the effort to better understand genetic determinants of disease, these whole genome sequences have less frequently been used to study another major determinant of ...
Brianna S. Chrisman +5 more
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Inherited chromosomally integrated human herpesvirus 6: regional variation in prevalence, association with angina, and identification of ancestral viral lineages in two large UK studies [PDF]
Journal of VirologyTens of millions of people worldwide have inherited chromosomally integrated human herpesvirus 6 (iciHHV-6), yet we know little about the consequences.
Michael L. Wood +39 more
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Meningoencephalitis in a background of inherited chromosomic integration of HHV-6 and CMV infection in an immunocompetent adult, which one is the culprit? [PDF]
IDCasesHHV-6 meningoencephalitis has been reported in immunocompromised individuals but is very uncommon in immunocompetent individuals. However, HHV-6 is the second most frequently detected virus in multiplex PCR tests. As HHV-6 DNA integrates in the telomeric
Anne-Laure Lajoye +3 more
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Case Report: Inherited chromosomally integrated HHV-6B in a pediatric medulloblastoma patient with encephalitis [PDF]
Frontiers in ImmunologyBackgroundHuman herpesvirus 6B (HHV-6B) is associated with various central nervous system (CNS) disorders, particularly in immunocompromised patients. We present a rare case of inherited chromosomally integrated HHV-6B (iciHHV-6B), also referred to as ...
Scott Sun +11 more
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Fetal cord plasma herpesviruses and preeclampsia: an observational cohort study [PDF]
Scientific ReportsA previous study suggested that fetal inheritance of chromosomally integrated human herpesvirus 6 (ici-HHV6) is associated with the hypertensive pregnancy disorder preeclampsia (PE). We aimed to study this question utilizing cord plasma samples (n = 1276)
Inka Häkkinen +13 more
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Endogenous human herpesviruses 6A/B [PDF]
Journal of VirologyHuman herpesviruses 6A and 6B (HHV-6A/B) can integrate into the germline, resulting in inherited viral DNA—now proposed to be called “endogenous HHV-6A/B (eHHV-6A/B).” Present in 0.2–3% of humans, this integrated DNA is passed to offspring and may ...
Louis Flamand +17 more
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Actualités sur la forme intégrée du génome du sixième herpesvirus humain au génome humain (iciHHV-6) [PDF]
médecine/sciences, 2017 A. Gautheret-Dejean
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