Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals. [PDF]
Elife, 2021 Human herpesviruses 6A and 6B (HHV-6A/6B) are ubiquitous pathogens that persist lifelong in latent form and can cause severe conditions upon reactivation.
Wood ML +14 more
europepmc +4 more sources
Summary of the 11th International Conference on Human Herpesviruses-6A, -6B, and -7. [PDF]
J Med Virol, 2020 Abstract The 11th International Conference on Human Herpesviruses (HHV)‐6A, ‐6B, and ‐7 was held in Quebec City, from 23 to 26 June 2019. It attracted 144 basic, translational, and clinical scientists from 20 countries. Important new information was presented regarding: the mechanisms of chromosomal integration for HHV‐6A and ‐6B; the biology of ...
Komaroff AL, Zerr DM, Flamand L.
europepmc +2 more sources
Journal of Medical Virology, Volume 95, Issue 1, January 2023., 2023 Abstract Human herpesvirus (HHV)‐6 and HHV‐7 have been detected in central nervous system and glioma tissue, while their exact role in glioma remains uncertain. Omics profiles and clinical information were downloaded from public databases, including The Cancer Genome Atlas cohort for training set and the Chinese Glioma Genome Atlas cohorts for ...
Luoyi Chen +6 more
wiley +1 more source
Pityriasis rosea in pregnancy: A case series and literature review
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 7, Page 953-959, July 2022., 2022 Summary Background and objective Pityriasis rosea (PR), a common skin disease in young adults, may adversely affects the course of pregnancy and the unborn child. Patients and methods Data from forty‐six pregnant women with PR seen in the dermatological university clinic between 2003 and 2018 were analyzed and compared with patient data (n = 53) from ...
Lena Wenger‐Oehn +6 more
wiley +1 more source
Pityriasis rosea in der Schwangerschaft: Eine Fallserie und Literaturübersicht
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 7, Page 953-960, July 2022., 2022 Zusammenfassung Hintergrund und Zielsetzung Pityriasis rosea (PR), eine häufige Hauterkrankung bei jungen Erwachsenen, kann den Verlauf der Schwangerschaft und das ungeborene Kind nachteilig beeinträchtigen. Patienten und Methodik Sechsundvierzig schwangere Frauen mit PR, die zwischen 2003 und 2018 an der dermatologischen Universität vorstellig waren ...
Lena Wenger‐Oehn +6 more
wiley +1 more source
Persistent viremia in an immunocompetent patient with inherited chromosomally integrated HHV-6B. [PDF]
Access Microbiol, 2021 Human herpesvirus-6 (HHV-6), the virus which causes roseola, has traditionally been associated with benign and self-limited childhood illness. However, HHV-6 establishes lifelong latency and can reactivate in immunocompromised adult patients. In about 1%
Obeid M, Gakhal I, McDonald PJ.
europepmc +2 more sources
Unique Challenges to Diagnosing Human Herpesvirus-6 (HHV-6) Encephalitis Following Post-Hematopoietic Stem Cell Transplant: A Case and Brief Review [PDF]
, 2022 A patient with an ultimate diagnosis of human herpesvirus-6 (HHV-6) encephalitis developed central nervous system (CNS) symptoms 13 days after undergoing myeloablative haploidentical allogeneic hematopoietic stem cell transplant (HSCT).
Ali, Amir +6 more
core +2 more sources
Impact of Host Telomere Length on HHV-6 Integration [PDF]
, 2022 Human herpesvirus 6A and 6B are two closely related viruses that infect almost all humans. In contrast to most herpesviruses, HHV-6A/B can integrate their genomes into the telomeres during the infection process.
Aimola, Giulia +4 more
core +1 more source
Characterization of human herpesvirus 6A/B U94 as ATPase, helicase, exonuclease and DNA-binding proteins [PDF]
, 2015 Human herpesvirus-6A (HHV-6A) and HHV-6B integrate their genomes into the telomeres of human chromosomes, however, the mechanisms leading to integration remain unknown. HHV-6A/B encode a protein that has been proposed to be involved in integration termed
Collin, Vanessa +8 more
core +1 more source
Fetal inheritance of chromosomally integrated human herpesvirus 6 predisposes the mother to pre-eclampsia. [PDF]
Nat Microbiol, 2020 Pre-eclampsia (typically characterized by new-onset hypertension and proteinuria in the second half of pregnancy) represents a major determinant of the global burden of disease1,2.
Gaccioli F +16 more
europepmc +3 more sources