Results 51 to 60 of about 471,112 (353)

Update on the psychometric properties and minimal important difference (MID) thresholds of the FACT-M questionnaire for use in treatment-naïve and previously treated patients with metastatic Merkel cell carcinoma

open access: yesHealth and Quality of Life Outcomes, 2020
Objectives For valid and reliable assessment of patients’ Health-Related Quality of Life (HRQoL), it is crucial to use psychometrically robust instruments.
Murtuza Bharmal   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

ICON: It's Not Just for Corrections Anymore, Data Download, Iowa Department of Corrections, January 2010 [PDF]

open access: yes, 2010
The Iowa Correctional Offender Network (ICON) is a data collection system that was first deployed in community corrections in 2000 after two years of planning, and was integrated with the institutions in 2004.

core  

Designing an Adaptive Interface: Using Eye Tracking to Classify How Information Usage Changes Over Time in Partially Automated Vehicles [PDF]

open access: yes, 2020
While partially automated vehicles can provide a range of benefits, they also bring about new Human Machine Interface (HMI) challenges around ensuring the driver remains alert and is able to take control of the vehicle when required.
Birrell, S.   +3 more
core   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Issues and development trends of modern Icon painting [PDF]

open access: yesSHS Web of Conferences, 2019
The article is concerned with topical issues and problem points of modern icon painting: understanding meanings and the mission of the icon in society, position of the Church, issue of the canon in icon painting, commercialization of the icon painter’s ...
Bobreshova Marina
doaj   +1 more source

The upper-atmosphere extension of the ICON general circulation model (version: Ua-icon-1.0) [PDF]

open access: yes, 2019
How the upper-atmosphere branch of the circulation contributes to and interacts with the circulation of the middle and lower atmosphere is a research area with many open questions.
Baldauf, M.   +5 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The ICON Single-Column Mode

open access: yesAtmosphere, 2021
The single-column mode (SCM) of the ICON (ICOsahedral Nonhydrostatic) modeling framework is presented. The primary purpose of the ICON SCM is to use it as a tool for research, model evaluation and development.
Ivan Bašták Ďurán   +10 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Home - About - Disclaimer - Privacy