Results 41 to 50 of about 47,347 (252)

Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Platelet‐derived growth factor is a major regulator of the vascular remodeling associated with pulmonary arterial hypertension. We previously showed that protein widely 1 (PW1+) vascular progenitor cells participate in early vessel ...
Julien Solinc, Jessica Raimbault‐Machado, France Dierick, Lamiaa El Bernoussi, Ly Tu, Raphaël Thuillet, Nathalie Mougenot, Bénédicte Hoareau‐Coudert, Virginie Monceau, Catherine Pavoine, Fabrice Atassi, David Sassoon, Giovanna Marazzi, Richard P. Harvey, Peter Schofield, Daniel Christ, Marc Humbert, Christophe Guignabert, Florent Soubrier, Sophie Nadaud   +19 more
doaj   +1 more source

The serotonin transporter promotes a pathological estrogen metabolic pathway in pulmonary hypertension via cytochrome P450 1B1 pulmonary circulation [PDF]

, 2016
Pulmonary arterial hypertension (PAH) is a devastating vasculopathy that predominates in women and has been associated with dysregulated estrogen and serotonin signaling. Overexpression of the serotonin transporter (SERT+) in mice results in an estrogen-
Anagnostopoulou, Aikaterini, Dean, Afshan, Hood, Katie, Johansen, Anne Katrine Z., Loughlin, Lynn, MacLean, Margaret R., Morecroft, Ian, Nilsen, Margaret, Touyz, Rhian M., White, Kevin   +9 more
core   +1 more source

“Nocturnal Seizures” in Idiopathic Pulmonary Arterial Hypertension [PDF]

Journal of Clinical Sleep Medicine, 2013
The usual differential diagnoses of nocturnal events in children include parasomnias, nocturnal seizures, nocturnal reflux (Sandifer syndrome), hypnic jerks, periodic limb movements of sleep, and sleep disordered breathing. We report a previously healthy young girl who presented to the sleep clinic for evaluation of nocturnal events which were ...
Anthony, Izzo, Julia, McSweeney, Thomas, Kulik, Umakanth, Khatwa, Sanjeev V, Kothare   +4 more
openaire   +2 more sources

Multiple congenital visceral abnormalities as a rare cause of pulmonary arterial hypertension

The Egyptian Heart Journal, 2022
Background Pulmonary arterial hypertension (PAH) is a rare, progressive disorder. PAH is caused by a wide spectrum of pathologies but the cause remains undetermined on many occasions and patients are classified in the idiopathic group.
Parham Rabiee, Sedigheh Saedi
doaj   +1 more source

A patient with severe idiopathic pulmonary arterial hypertension: Is there a way out? [PDF]

Терапевтический архив, 2017
The paper considers a clinical example of current therapy for idiopathic pulmonary arterial hypertension in a female patient with its clinical deterioration.
N A Tsareva, S N Avdeev, G V Neklyudova
doaj   +1 more source

Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias [PDF]

, 2015
Background Pulmonary hypertension (PH) is a common finding in patients with chronic fibrosing idiopathic interstitial pneumonias (IIP). Little is known about the response to pulmonary vasodilator therapy in this patient population.
Behr, Juergen, Claussen, Martin, Distler, Oliver, Gibbs, J. Simon R., Grohé, Christian, Grunig, Ekkehard, Held, Matthias, Hoeper, Marius M., Huscher, Doerte, Klose, Hans, Kuwana, Masataka, Lange, Tobias J., Neurohr, Claus, Olsson, Karen M., Opitz, Christian, Pittrow, David, Vizza, C. Dario, Vonk-Noordegraaf, Anton, Wirtz, Hubert, Zelniker, Thomas   +19 more
core   +6 more sources

Pulmonary Artery Pulse Wave Velocity in Idiopathic Pulmonary Arterial Hypertension

Canadian Journal of Cardiology, 2013
Idiopathic pulmonary artery (PA) hypertension (IPAH) is associated with severe PA remodelling. Although the resulting increase in pulse wave velocity (PWV) might be of major pathophysiological relevance, little is known about PA-PWV in IPAH. The aim of this study was to characterize PA-PWV and its predictors in patients with IPAH.We studied 26 ...
Kopeć, Grzegorz, Moertl, Deddo, Jankowski, Piotr, Tyrka, Anna, Sobień, Bartosz, Podolec, Piotr   +5 more
openaire   +3 more sources

Circulating angiopoietins in idiopathic pulmonary arterial hypertension [PDF]

European Heart Journal, 2010
To determine the diagnostic utility of circulating angiopoietin-1 (Ang-1) and its antagonist angiopoietin-2 (Ang-2) as potential biomarkers of disease severity or response to treatment in idiopathic pulmonary arterial hypertension (IPAH). Imbalances in angiogenic factors including vascular endothelial cell growth factor (VEGF) and the angiopoetin-Tie2 ...
Philipp, Kümpers, Nils, Nickel, Alexander, Lukasz, Heiko, Golpon, Volker, Westerkamp, Karen M, Olsson, Danny, Jonigk, Lavinia, Maegel, Clemens L, Bockmeyer, Sascha, David, Marius M, Hoeper   +10 more
openaire   +2 more sources

Pulmonary Hypertension Registry: a single-center experience in Egypt

Egyptian Journal of Chest Disease and Tuberculosis, 2020
Introduction Pulmonary hypertension is a life-threatening progressive disease that eventually leads to disability and death. Aim To establish the first single-center registry for pulmonary hypertension in Egypt, Kasr Al-Ainy Hospitals, Cairo University ...
Youssef A Soliman, Reem Elkorashy, Eman Kamal, Mohamed S Ismail, Yasmine H El-Hinnawy, Hassan G Yamamah, Ahmed Abd El Aziz, Hussein Heshmat, Kareem Mahmoud, Hala El-Gunidy, Mostafa El Shazly, Medhat Soliman   +11 more
doaj   +1 more source

Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival [PDF]

, 2017
In pulmonary hypertension (PH), right ventricular (RV) performance determines survival. Pulmonary artery (PA) stiffening is an important biomechanical event in PH and also predicts survival based on the PA relative area change (RAC) measured at rest ...
Bellofiore, Alessandro, Blyth, Kevin G., Chesler, Naomi C., Foster, John E., Jayasekera, Geeshath, Peacock, Andrew J., Steedman, Tracey   +6 more
core   +1 more source