Results 151 to 160 of about 4,006,149 (207)

Spatial habitat radiomics predicts tertiary lymphoid structure status and identifies an IDO1⁺ migratory dendritic cell axis in breast cancer. [PDF]

J Immunother Cancer
Yu Y, Wang Q, Lin Y, Huang K, Wang R, Wang J, Huang X, Zhang J, Chen W, Chen R, Chen X, Meng F, Zhang H, Yuan J, Lin J, Song C.   +15 more
europepmc   +1 more source

Lipophilic Ligand Efficiency-Monitored Discovery of Potent, Achiral, and Bioavailable Apo-IDO1 Inhibitors. [PDF]

ACS Med Chem Lett
Kazmierski WM, Miriyala N, De la Rosa M, Miller J, Gentry ZO, Samano V, Catalano J, Chong PY, Wang F, Price DJ, Basilla J, Mebrahtu M, Wang L, Shewchuk L, Matico R, Dunham R.   +15 more
europepmc   +1 more source

Discovery of a Dual IDO1/TDO Inhibitor That Modulates Enzymatic Activity and IDO1/SHP-2 Signaling. [PDF]

J Med Chem
Rezzi SJ, Butticè A, Villani S, Lesca G, Rossini S, Panfili E, Mazzoletti D, Bari E, Violante D, Serafini M, Massarotti A, Orabona C, Pallotta MT, Aprile S, Fallarini S, Del Grosso E, Di Martino RMC, Miggiano R, Pirali T.   +18 more
europepmc   +1 more source

Differentiation therapy targeting indoleamine 2,3-dioxygenase 1 in glioblastoma cells <i>in vitro</i>. [PDF]

Mol Clin Oncol
Nishide K, Yamamuro S, Aida Y, Ozawa Y, Sano E, Yoshino A.   +5 more
europepmc   +1 more source

Editorial Comment on "Stage-Dependent Changes in Kynurenine Pathway Enzyme Expression Suggest Immune-Related Involvement in Bladder Cancer Progression": Rethinking the Tryptophan-Kynurenine Pathway in Urological Cancer Immunotherapy. [PDF]

Int J Urol
Almulla AF, Zhang Y, Maes M.
europepmc   +1 more source

Resistance mechanisms and countermeasures in CLDN18.2-positive tumors: from molecular networks to clinical practice. [PDF]

Front Oncol
Xia Y, Wang M, Huang T, Sun K, Wang P.
europepmc   +1 more source

The role of the kynurenine pathway in the pathogenesis of pain and affective disorders after traumatic brain injury. [PDF]

Brain Behav Immun Health
Nahmoud I, Monahan K, Woodcock EA, Conti AC.   +3 more
europepmc   +1 more source

Cobalt-mediated suppression of IFN-γ-JAK-STAT1 signaling reprograms IDO1-driven immunosuppression for metalloimmunotherapy. [PDF]

Sci Adv
Jiang T, Huang X, Wu Z, Abudusaimaiti G, Song Y, Duan H, Zhou Y, Chen Y, Du S, Zhang H, Qian J, Zhang Y.   +11 more
europepmc   +1 more source

Targeting the AHR-IDO1-kynurenine pathway in TREM2⁺ macrophages restores antitumor immunity in thyroid cancer. [PDF]

Front Immunol
Le F, Huang X, Jiang Y, Lv S, Chen Y.
europepmc   +1 more source

Phytochemical Modulation of the Kynurenine Pathway (KYNP) and Its Emerging Mechanistic Insights into Cancer Progression: A Systematic Review. [PDF]

Int J Mol Sci
Tsantila EM, Christodoulou MC, Esslinger N, Neophytou CM.   +3 more
europepmc   +1 more source