Results 161 to 170 of about 4,006,149 (207)

Drug Discovery of Allosteric Molecular Glue Degraders (aMGDs): Expanding the Landscape of Targeted Protein Degradation. [PDF]

J Med Chem
Xue Y, Ali S, Chen H, Zhou J.
europepmc   +1 more source

Human lncRNA, hLinfRNA7 (IDO1-AS) Regulates Cytokine Expression, Tryptophan Catabolism, and Inflammatory Response in Macrophage. [PDF]

Mol Cell Biol
Rishi A, Guha P, Bhat N, Chini A, Gondrala PK, Mandal SS.   +5 more
europepmc   +1 more source

Interleukin-6 Downregulates T Helper 17 Cytokines via Indoleamine 2,3-Dioxygenase 1 at the Maternal-Fetal Interface. [PDF]

Am J Reprod Immunol
Tang X, Dao S, Luo J, Chen X, Weng Y, Yin G, Xiao Z, Zhao S, Huang G.   +8 more
europepmc   +1 more source

Tanshinone IIA restores CD8⁺ T-cell immunity in TNBC by suppressing the IDO1-kynurenine axis. [PDF]

Front Pharmacol
Qiu Z, Meng C, Tang M.
europepmc   +1 more source

Targeting tryptophan metabolism in breast cancer immunotherapy: Recent advances and future prospects. [PDF]

Transl Oncol
Li G, Zhou H, Shen X, Ying P, Lu H.
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Morpholine-Coumarin Derivatives for Inflammation-Associated Depression. [PDF]

Biomolecules
Liu H, Hu L, Wang Y, Quan Z, Liu Z, Wang S, Shen Q.   +6 more
europepmc   +1 more source

H₂S induces apoptosis of tumors with high IDO1 expression via NR4A1-BCL-2 and SOCS3 pathways. [PDF]

Cell Mol Biol Lett
He ZNT, Meng F, Qian X, Liu Y, Fang X, Yang D, Yang Q.   +6 more
europepmc   +1 more source

Stage-Dependent Changes in Kynurenine Pathway Enzyme Expression Suggest Immune-Related Involvement in Bladder Cancer Progression. [PDF]

Int J Urol
Lemes DE, Santos AÁS, de Oliveira JL, Roman-Ramos H, Moreno ACR, Camacho CP, Pontes-Junior J, Dellê H.   +7 more
europepmc   +1 more source

Therapeutic remodeling of the tuberculosis granuloma with 1-methyl-D-tryptophan enhances CD8⁺ T cell-macrophage interactions. [PDF]

Proc Natl Acad Sci U S A
McCaffrey EF, Delmastro AC, Singh B, Devi A, Munson CW, Priyanka, Golden NA, Khader SA, Angelo M, Kaushal D, Mehra S.   +10 more
europepmc   +1 more source

Combine immune checkpoint indoleamine 2,3-dioxygenase 1 knockdown with ferroptosis inducer Erastin/RSL3 accelerates colorectal cancer cell ferroptosis. [PDF]

Cytojournal
Li F, Xu T, Ling Y, Xu J, Zhang X, Sun S.   +5 more
europepmc   +1 more source