Results 1 to 10 of about 177,776 (291)

Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats

Исследования и практика в медицине, 2021
Purpose of the study. Diabetes mellitus (DM) is considered an independent risk factor for higher cancer incidence and death rates. The system of insulin-like growth factors and their carrier proteins (IGF and IGFBP) and hyperglycemia create favorable ...
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, N. D. Cheryarina, P. S. Kachesova, L. A. Nemashkalova   +8 more
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Whole-brain characterization of apoptosis after sevoflurane anesthesia reveals neuronal cell death patterns in the mouse neonatal neocortex

Scientific Reports, 2023
In the last two decades, safety concerns about general anesthesia (GA) arose from studies documenting brain cell death in various pharmacological conditions and animal models.
Julie Areias, Chrystelle Sola, Yan Chastagnier, Julien Pico, Nathalie Bouquier, Christophe Dadure, Julie Perroy, Vivien Szabo   +7 more
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Hif-1α and IGF Expression in Endometrial Hyperplasia

Journal of Education, Health and Sport, 2020
The objective: to assess the effect of insulin resistance and hypoxia on the risk of endometrial hyperplasia development. The research was conducted on the base of Municipal Maternity House №5 (Odessa, Ukraine).
Z. V. Chumak, M. V. Shapoval, O. G. Andrievskiy   +2 more
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Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies

Communications Chemistry, 2023
The polyhistidine (6XHis) motif is one of the most ubiquitous protein purification tags. The 6XHis motif enables the binding of tagged proteins to various metals, which can be advantageously used for purification with immobilized metal affinity ...
Robert D. Healey, Louise Couillaud, François Hoh, Assia Mouhand, Aurelien Fouillen, Pierre Couvineau, Sébastien Granier, Cédric Leyrat   +7 more
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Effect of different dietary zinc sources on the semen quality, testicular histology and sex hormone concentration in broiler breeder roosters

Italian Journal of Animal Science, 2021
The aim of the present study was to evaluate the effect of different dietary zinc sources (ZnSO4, Zinc-amino acid and Zn5(OH)2Cl2H2O), on hormone levels, testicular histology and sperm quality in broiler breeder roosters.
Mehdi Jafari, Mehrdad Irani, Vahid Rezaeipour   +2 more
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Early 5‐HT6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse

EMBO Molecular Medicine, 2020
Cannabis abuse during adolescence confers an increased risk for developing later in life cognitive deficits reminiscent of those observed in schizophrenia, suggesting common pathological mechanisms that remain poorly characterized.
Coralie Berthoux, Al Mahdy Hamieh, Angelina Rogliardo, Emilie L Doucet, Camille Coudert, Fabrice Ango, Katarzyna Grychowska, Séverine Chaumont‐Dubel, Pawel Zajdel, Rafael Maldonado, Joël Bockaert, Philippe Marin, Carine Bécamel   +12 more
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Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model

Frontiers in Molecular Neuroscience, 2017
Fragile X syndrome (FXS) is a genetic disorder due to the silencing of the Fmr1 gene, causing intellectual disability, seizures, hyperactivity, and social anxiety. All these symptoms result from the loss of expression of the RNA binding protein fragile X
Laura Ceolin, Nathalie Bouquier, Jihane Vitre-Boubaker, Stéphanie Rialle, Dany Severac, Emmanuel Valjent, Julie Perroy, Emma Puighermanal   +7 more
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The effect of liquorice (Glycyrrhiza glabra) extract on IGF, TNF and lyzozyme genes expression in Cyprinus carpio fingerlings [PDF]

بوم‌شناسی آبزیان, 2023
The study aimed to assess the impact of Glycyrrhiza glabra extract on IGF, TNF, and lysozyme gene expression in Cyprinus carpio. Fish, averaging 9.08±0.05 grams, were distributed across 12 tanks and subjected to three levels of G. glabra extract (0, 0.5,
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Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice

Journal of Neuroinflammation, 2022
Background Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD).
Anne-Laure Hemonnot-Girard, Cédric Meersseman, Manuela Pastore, Valentin Garcia, Nathalie Linck, Catherine Rey, Amine Chebbi, Freddy Jeanneteau, Stephen D. Ginsberg, Joël Lachuer, Christelle Reynes, François Rassendren, Hélène Hirbec   +12 more
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FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

Nature Communications, 2021
The demethylase FTO was shown to remove on N6-methyladenosine (m6A) and N6, 2’-O-dimethyladenosine (m6Am) modifications on RNAs. Here the authors show that FTO impedes cancer stem cell-like abilities in colorectal cancer cells through its m6Am ...
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David   +21 more
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