Results 1 to 10 of about 147,758 (99)

Neuroprotection of IGF-1 in neonatal hypoxic-ischemic brain injury through downregulation of FoXO3a-PUMA pathway [PDF]

open access: yesFrontiers in Cellular Neuroscience
Insulin-like growth factor-1 (IGF-1) is a single chain polypeptide hormone that plays an essential role in intrauterine and postnatal growth. Recent studies suggest that IGF-1 and its receptor IGF-1R are involved in the pathogenesis of neurological ...
Yanli Tang   +12 more
doaj   +2 more sources

Un viaggio nella Gestalt: come cambia il benessere durante il percorso gestaltico

open access: yesPhenomena Journal, 2023
Questo lavoro riporta alcuni risultati preliminari di un progetto di ricerca volto a indagare il rapporto tra il benessere percepito e il lavoro personale in psicoterapia della Gestalt.
Stefano Roti 1 , Francesca Berti 1 , Nino Geniola2 , Susanna Zajotti 1 , Giulia Calvaresi 1 , Matteo Defraia1 , Alessandro Cini 1
doaj   +1 more source

Research progress of IGF‐1 and cerebral ischemia

open access: yesIbrain, 2021
Cerebral ischemic disease is a group of diseases that cause insufficient blood supply to the cerebrum, cerebellum or brain stem for different reasons, resulting in corresponding nervous system symptoms.
Shun‐Lian Li   +3 more
doaj   +1 more source

The IGF-1 Signaling Pathway in Viral Infections

open access: yesViruses, 2021
Insulin-like growth factor-1 (IGF-1) and the IGF-1 receptor (IGF-1R) belong to the insulin-like growth factor family, and IGF-1 activates intracellular signaling pathways by binding specifically to IGF-1R.
Agata Józefiak   +3 more
doaj   +1 more source

New insights on the cardiovascular effects of IGF-1

open access: yesFrontiers in Endocrinology, 2023
IntroductionCardiovascular (CV) disorders are steadily increasing, making them the world’s most prevalent health issue. New research highlights the importance of insulin-like growth factor 1 (IGF-1) for maintaining CV healthMethodsWe searched PubMed and ...
Mirjana Macvanin   +7 more
doaj   +1 more source

Elevated serum concentrations of IGF-1 and IGF-1R in patients with thyroid cancers

open access: yesBiomedical Papers, 2020
Background: The rising incidence of thyroid cancer observed in the last few decades requires an improvement in diagnostic tools and management techniques for patients with thyroid nodules. Aims: The aim of this study was to assess serum concentrations of
Hanna Lawnicka   +7 more
doaj   +1 more source

Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets

open access: yesFrontiers in Oncology, 2021
AimInsulin-like growth factor-1 receptor (IGF-1R) is one of the main members of the tyrosine protein kinase receptor family. This receptor binds insulin-like growth factor-1 (IGF-1) with a high affinity. IGF-1 is a member of a family of proteins involved
Yinqi Zhang   +17 more
doaj   +1 more source

Genetic and dietary determinants of insulin-like growth factor (IGF)-1 and IGF binding protein (BP)-3 levels among Chinese women. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Higher insulin-like growth factor (IGF)-1 and lower IGF binding protein (BP)-3 levels have been associated with higher commoncancer risk, including breast cancer.
Qiong Wang   +9 more
doaj   +1 more source

Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports

open access: yesBiomolecules, 2021
Insulin-like growth factor-1 (IGF-1) is the principal mediator of growth hormone (GH), plays a crucial role in promoting cell growth and differentiation in childhood and continues to have an anabolic effect in adults.
Julian Bailes, Mikhail Soloviev
doaj   +1 more source

Cyclic Glycine-Proline (cGP) Normalises Insulin-Like Growth Factor-1 (IGF-1) Function: Clinical Significance in the Ageing Brain and in Age-Related Neurological Conditions

open access: yesMolecules, 2023
Insulin-like growth factor-1 (IGF-1) function declines with age and is associated with brain ageing and the progression of age-related neurological conditions.
Jian Guan   +7 more
doaj   +1 more source

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