Results 11 to 20 of about 112,948 (243)
Liver-derived IGF-I regulates mean life span in mice. [PDF]
PLoS ONE, 2011 BACKGROUND: Transgenic mice with low levels of global insulin-like growth factor-I (IGF-I) throughout their life span, including pre- and postnatal development, have increased longevity.
Johan Svensson +6 more
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IGF-I binding proteins, IGF-I binding protein mRNA and IGF-I receptor mRNA in rats with acute renal failure given IGF-I [PDF]
Kidney International, 1998 Recombinant human insulin-like growth factor-I (rhIGF-I) accelerates recovery from acute renal failure (ARF) in rats. IGF-I acts through the IGF-I receptor (IGF-IR) and its actions may be modified by IGF-I binding proteins (IGFBPs). It therefore would be of value to determine the effects of both ARF and rhIGF-I treatment on serum IGFBPs and mRNA for ...
BohÉ, Julien +6 more
openaire +2 more sources
Frontiers in Endocrinology, 2013 Insulin-like growth factor I (IGF-I) has been implicated in the pathogenesis of prostate cancer (PCa), since it plays a key role in cell proliferation, differentiation and apoptosis. The IGF-I actions are mediated mainly via its binding to the type I IGF
Anastassios ePhilippou +2 more
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Journal of Neuroinflammation, 2011 Background Insulin-like growth factor-I (IGF-I) exerts neuroprotective actions in the central nervous system that are mediated at least in part by control of activation of astrocytes. In this study we have assessed the efficacy of exogenous IGF-I and IGF-
Goya Rodolfo G +3 more
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BMC Cancer, 2011 Background Epidemiological evidence suggests that moderately elevated levels of circulating insulin-like growth factor-I (IGF-I) are associated with increased risk of breast cancer in women.
Brown Powel H +7 more
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The neuroprotective effects of intramuscular insulin-like growth factor-I treatment in brain ischemic rats. [PDF]
PLoS ONE, 2013 Brain ischemia leads to muscle inactivity-induced atrophy and may exacerbate motor function deficits. Intramuscular insulin-like growth factor I (IGF-I) injection has been shown to alleviate the brain ischemia-induced muscle atrophy and thus improve the ...
Heng-Chih Chang +4 more
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Journal of Immunology Research, 2021 Leishmaniases are diseases caused by several Leishmania species, and many factors contribute to the development of the infection. Because the adaptive immune response does not fully explain the outcome of Leishmania infection and considering that the ...
Luiza C. Reis +7 more
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IGF-I Bioactivity Better Reflects Growth Hormone Deficiency than Total IGF-I [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2011 GH is considered the main regulator of circulating IGF-I. Total (extractable) IGF-I is therefore routinely used for diagnosis of GH deficiency (GHD) and for monitoring treatment. Methods currently used for measurement of circulating total IGF-I may be hampered by interferences of IGF-binding proteins.
Varewijck, Aimee +4 more
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Zmiany w stężeniach insulinopodobnych czynników wzrostu IGF-1 i IGF-2 i białek wiążących BP-2 i BP-3 w czasie leczenia ostrej białaczki limfoblastycznej [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2004 Cel pracy: Ocena dynamiki zmian w wartościach insulinopodobnych czynników wzrostu: IGF-1 i IGF-2 i białek wiążących: IGFBP-2 i IGFBP-3 w surowicy krwi dzieci z ostrą białaczką limfoblastyczną (ALL) w trakcie leczenia przeciwnowotworowego.
Maryna Krawczuk-Rybak +2 more
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Little effects of Insulin-like Growth Factor-I on testicular atrophy induced by hypoxia
BMC Urology, 2006 Background Insulin-like Growth Factor-I (IGF-I) supplementation restores testicular atrophy associated with advanced liver cirrhosis that is a condition of IGF-I deficiency.
Casares Amelia +8 more
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