Results 211 to 220 of about 152,806 (342)

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive ...
Volker Siffrin
wiley   +1 more source

Rejuvenating the gut: young plasma therapy improves cell proliferation, IGF-I and IGF-IR expression, and immune defense in aged male rats jejunum. [PDF]

Biogerontology
Asmaz ED, Tan M, Genç AI, Teker HT, Ceylani T.   +4 more
europepmc   +1 more source

Increased GH/IGF-I Axis Activity Relates to Lower Hepatic Lipids and Phosphor Metabolism.

J Clin Endocrinol Metab, 2023
Fellinger P, Beiglböck H, Semmler G, Pfleger L, Smajis S, Baumgartner C, Gajdosik M, Marculescu R, Vila G, Winhofer Y, Scherer T, Trauner M, Kautzky-Willer A, Krssak M, Krebs M, Wolf P.   +15 more
europepmc   +1 more source

Free Insulin-like Growth Factor (IGF)-I in Children with PWS. [PDF]

J Clin Med, 2022
Damen L, Elizabeth MSM, Donze SH, van den Berg SAA, de Graaff LCG, Hokken-Koelega ACS.   +5 more
europepmc   +1 more source

Insulin-Like Growth Factor-I (IGF-I) Concentration in 150-Kilodalton Complexes Containing Human IGF-Binding Protein-3 (hIGFBP-3) after Intravenous Injection of Adult Rats with hIGFBP-3 [PDF]

, 1997
C. Young Lee, Haibin Wu, Dae‐Shik Suh, Matthew M. Rechler   +3 more
openalex   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Regulation of cell surface GLUT1, GLUT3, and GLUT4 by insulin and IGF‐I in L6 myotubes [PDF]

, 1995
Cindy M. Wilson, Yasuhide Mitsumoto, Fran Maher, Amira Klip   +3 more
openalex   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

International Journal of Cancer, EarlyView.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai, Chunyan Luan, Zhesi Zhang, Anja Wessely, Markus V. Heppt, Carola Berking, Julio Vera   +6 more
wiley   +1 more source

Growth hormone/IGF-I-dependent signaling restores decreased expression of the myokine SPARC in aged skeletal muscle. [PDF]

J Mol Med (Berl), 2022
Mathes S, Fahrner A, Luca E, Krützfeldt J.   +3 more
europepmc   +1 more source

Use of Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein Measurements to Monitor Feeding of Premature Infants¹ [PDF]

, 1997
W. J. Bernhard Smith, Louis E. Underwood, Lynette L. Keyes, David R. Clemmons   +3 more
openalex   +1 more source