Results 241 to 250 of about 14,093,235 (401)

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Nutrition, GH/IGF-1 signaling, and cancer. [PDF]

Endocr Relat Cancer
Fanti M, Longo VD.
europepmc   +1 more source

Inhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro

, 1999
Valér Csernus, Andrew V. Schally, Hippokratis Kiaris, Patricia Armatis   +3 more
openalex   +2 more sources

IGF I (INSULIN-LIKE GROWTH FACTOR I) INDUIT LA PRODUCTION DU CORTISOL ET DE L'ANDROSTENEDIONE DANS LA CELLULE CORTICO-SURRENALIENNE BOVINE [PDF]

, 1989
MT Pham-Huu-trung, M Binoux
openalex   +1 more source

Meta-analysis and dose-response metaregression: circulating insulin-like growth factor I (IGF-I) and mortality.

Journal of Clinical Endocrinology and Metabolism, 2011
A. Burgers, N. Biermasz, J. Schoones, A. Pereira, A. Renehan, M. Zwahlen, M. Egger, O. Dekkers   +7 more
semanticscholar   +1 more source

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, EarlyView.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source

Rejuvenating the gut: young plasma therapy improves cell proliferation, IGF-I and IGF-IR expression, and immune defense in aged male rats jejunum. [PDF]

Biogerontology
Asmaz ED, Tan M, Genç AI, Teker HT, Ceylani T.   +4 more
europepmc   +1 more source

Microglia-mediated IGF-I neuroprotection in the rd10 mouse model of retinitis pigmentosa.

Investigative Ophthalmology and Visual Science, 2011
A. Arroba, Noemí Álvarez-Lindo, N. Van Rooijen, E. J. de la Rosa   +3 more
semanticscholar   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

A phase I trial of vertical inhibition of IGF signalling using cixutumumab, an anti-IGF-1R antibody, and selumetinib, an MEK 1/2 inhibitor, in advanced solid tumours [PDF]

, 2014
Breelyn A. Wilky, Michelle A. Rudek, Shabina Roohi Ahmed, Dan Laheru, David Cosgrove, Ross C. Donehower, Barry D. Nelkin, Douglas W. Ball, L. Austin Doyle, H Chen, Xiquan Ye, Graham Bigley, Chris Womack, Nilofer S. Azad   +13 more
openalex   +1 more source