Results 51 to 60 of about 152,806 (342)

X‐Ray Computed Tomography Quantifies Primary Phases and Reveals Crack Morphology in High‐Cycle Fatigue of Aluminum Alloy EN AW‐2618A

open access: yesAdvanced Engineering Materials, EarlyView.
Primary phases and a fatigue crack are studied in a forged blank of an aluminum alloy using synchrotron and laboratory X‐ray computed tomography. To image the crack, the fatigue test is interrupted, and a static tensile load is applied to open the crack.
Jakob Schröder   +6 more
wiley   +1 more source

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

open access: yes, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, Pirianov, G
core   +2 more sources

Combining Metal Additive Manufacturing and Casting Technology: High Performance Cooling Channels for Electric Powertrain Components

open access: yesAdvanced Engineering Materials, EarlyView.
When realized as inserts in high‐pressure die casting, aluminum cooling channels for electric powertrain components and similar applications typically require a stabilizing filler to survive the process. The present study investigates relinquishing this filler using additively manufactured inserts promising performance improvements.
Dirk Lehmhus   +9 more
wiley   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

open access: yesAdvanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue   +3 more
wiley   +1 more source

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury [PDF]

open access: yes, 2005
BACKGROUND/AIM: Hepatic stellate cells (HSCs) express alpha-smooth muscle actin (alphaSMA) and acquire a profibrogenic phenotype upon activation by noxious stimuli.
Brenner, D.A. (D. A.)   +11 more
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

The IGF-I axis in kidney and skeletal muscle of potassium deficient rats [PDF]

open access: yes, 1997
The IGF-I axis in kidney and skeletal muscle of potassium deficient rats. Potassium deficiency in the rat results in growth retardation, muscle wasting and renal hypertrophy.
Hsu, Fay W., Rabkin, Ralph, Tsao, Tanny
core   +1 more source

PEGylated insulin-like growth factor-I affords protection and facilitates recovery of lost functions post-focal ischemia

open access: yesScientific Reports, 2017
Insulin-like growth factor-I (IGF-I) is involved in the maturation and maintenance of neurons, and impaired IGF-I signaling has been shown to play a role in various neurological diseases including stroke.
Kim Parker   +6 more
doaj   +1 more source

Insulin-Like Growth Factor I Receptor (IGF-IR) Ligands and BMI in Squamous Intra-Epithelial Lesion (SIL) of Cervix [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Cancer cervix is the most common cancer in women in developing countries like India. Several studies have linked insulin-like growth factors-I & II (IGF-I and IGF-II) and IGF binding proteins-3 (IGFBP-3) with pathogenesis of Squamous ...
Praveen Sablania   +2 more
doaj   +1 more source

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John   +5 more
wiley   +1 more source

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