Results 21 to 30 of about 150,785 (321)

Effect of different dietary zinc sources on the semen quality, testicular histology and sex hormone concentration in broiler breeder roosters

Italian Journal of Animal Science, 2021
The aim of the present study was to evaluate the effect of different dietary zinc sources (ZnSO4, Zinc-amino acid and Zn5(OH)2Cl2H2O), on hormone levels, testicular histology and sperm quality in broiler breeder roosters.
Mehdi Jafari, Mehrdad Irani, Vahid Rezaeipour   +2 more
doaj   +1 more source

The effect of powder peppermint on GH and IGF gene expression and hematology in Caspian roach (Rutilus caspicus) [PDF]

بوم‌شناسی آبزیان, 2019
In recent years, the administration of medicinal herbs as growth and innate immune stimulator has been increasing in fish. In this study, the effect of peppermint powder on GH and IGF gene expression and hematology was studied In Caspian roach (Rutilus ...
Hamed Paknejad, Abdolmajid Hajimoradloo, Soheila Rastgari, Marjan Hosseini, Hamed Azadi   +4 more
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Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy

Nature Communications, 2018
Alkaline ceramidases (ACERs) are a class of poorly understood transmembrane enzymes controlling the homeostasis of ceramides. Here authors solve the Xray structure of human ACER3 and uncover a Ca2+ binding site providing an explanation for the known ...
Ieva Vasiliauskaité-Brooks, Robert D. Healey, Pascal Rochaix, Julie Saint-Paul, Rémy Sounier, Claire Grison, Thierry Waltrich-Augusto, Mathieu Fortier, François Hoh, Essa M. Saied, Christoph Arenz, Shibom Basu, Cédric Leyrat, Sébastien Granier   +13 more
doaj   +1 more source

AIMTOR, a BRET Biosensor for Live Recording of mTOR Activity in Cell Populations and Single Cells

Bio-Protocol, 2021
Mammalian target of rapamycin (mTOR) controls many crucial cellular functions, including protein synthesis, cell size, energy metabolism, lysosome and mitochondria biogenesis, and autophagy.
Nathalie Bouquier, Enora Moutin, Julie Perroy, Vincent Ollendorff   +3 more
doaj   +1 more source

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract

Cancer Communications, Volume 42, Issue 12, Page 1367-1386, December 2022., 2022
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlying genetic basis and heterogeneity of GI‐NECs.
Huanwen Wu, Zicheng Yu, Yueping Liu, Lei Guo, Lianghong Teng, Lingchuan Guo, Li Liang, Jing Wang, Jie Gao, Ruiyu Li, Ling Yang, Xiu Nie, Dan Su, Zhiyong Liang   +13 more
wiley   +1 more source

Dominant role of GABAB2 and Gbetagamma for GABAB receptor-mediated-ERK1/2/CREB pathway in cerebellar neurons [PDF]

Cellular Signalling 19, 9 (2007) 1996-2002, 2008
gamma-aminobutyric acid type B (GABA(B)) receptor is an allosteric complex made of two subunits, GABA(B1) and GABA(B2). GABA(B2) plays a major role in the coupling to G protein whereas GABA(B1) binds GABA. It has been shown that GABA(B) receptor activates ERK(1/2) in neurons of the central nervous system, but the molecular mechanisms underlying this ...
arxiv   +1 more source

IGF-1 Gene Polymorphism and its Association with Cashmere Fiber Trait in Changthangi Goats

Journal of Natural Fibers, 2020
The Cashmere (Pashmina) fiber attracts great demand worldwide for its fineness. To identify and determine the role of Insulin-like Growth Factor-1 (IGF-1) gene polymorphism on Pashmina fiber traits (quality and quantity), exon IV, and part of intron IV ...
Syed Shanaz, Tasleem Ahmad Shamas Ganai, Ishraq Hussain, Sheikh Firdous Ahmad, Feroz Din Sheikh, Nadeem Shabir, Nusrat Nabi, Nazir A Ganai   +7 more
doaj   +1 more source

Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors

Membranes, 2023
G-protein coupled receptors (GPCRs) are versatile signaling proteins that regulate key physiological processes in response to a wide variety of extracellular stimuli. The last decade has seen a revolution in the structural biology of clinically important
Aurélien Fouillen, Julien Bous, Sébastien Granier, Bernard Mouillac, Remy Sounier   +4 more
doaj   +1 more source

Application of biologics for ridge preservation/reconstruction after implant removal

Clinical Advances in Periodontics, Volume 12, Issue 4, Page 270-276, December 2022., 2022
Abstract Background The purpose of this review was aimed at providing the rationale supported with a series of cases to apply biologics to enhance orchestrating the healing process at implant removal sites. Summary Implant removal is commonly applied on a daily basis, in particular, in cases that exhibit esthetic failures linked to inadequate implant ...
Alberto Monje, Fernando Suárez‐López del Amo   +1 more
wiley   +1 more source

The effect of liquorice (Glycyrrhiza glabra) extract on IGF, TNF and lyzozyme genes expression in Cyprinus carpio fingerlings [PDF]

بوم‌شناسی آبزیان, 2023
The study aimed to assess the impact of Glycyrrhiza glabra extract on IGF, TNF, and lysozyme gene expression in Cyprinus carpio. Fish, averaging 9.08±0.05 grams, were distributed across 12 tanks and subjected to three levels of G. glabra extract (0, 0.5,
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