Results 81 to 90 of about 7,271 (197)

Table1_AhR Antagonist Promotes Differentiation of Papillary Thyroid Cancer via Regulating circSH2B3/miR-4640-5P/IGF2BP2 Axis.xlsx

, 2021
Abnormally high expression of aryl hydrocarbon receptor (AhR) has been implicated in dedifferentiation of radioiodine-refractory papillary thyroid cancer (RR-PTC).
Meiliang Guo (11871101), Feng Guan (725911), Ri Sa (11871098), Danyan Liu (11871104)   +3 more
core   +1 more source

Interactive Effect of IGF2BP2 rs4402960 Variant, Smoking and Type 2 Diabetes

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2020
Genetic and environmental factors are related to type 2 diabetes (T2D). Genetic modifiers of T2D have not been widely determined among smoking individuals. In this population-based study, we investigated the interactive association between rs4402960 polymorphism of the insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) gene and smoking with ...
Oswald Ndi Nfor, Nokuphila Balindile Ndzinisa, Meng‑Hsiun Tsai, Chih-Hsuan Hsiao, Yung-Po Liaw   +4 more
openaire   +4 more sources

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, Volume 13, Issue 56, 9 October 2026.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Вклад полиморфизма rs11927381 гена IGF2BP2 в патогенез сахарного диабета 2 типа [PDF]

, 2020
Изучение связи полиморфизма гена IGF2BP2, (rs11927381, Т>С) с риском развития СД2 у жителей Курской ...
Азарова, Ю. Э., Ковалев, А. П., Клесова, Е. Ю., Сакали, С. Ю.   +3 more
core   +1 more source

LncRNA TMEM99 Complexes with IGF2BP2 to Inhibit Autophagy in Lung Adenocarcinoma

Advanced Science
Abstract Lung adenocarcinoma (LUAD), the most common type of lung cancer, has a poor prognosis. Long noncoding RNAs (lncRNAs) play a key role in LUAD progression, yet the biological role of lncRNA TMEM99 remains unexplored. In this study, its function in inhibiting autophagy in LUAD is explored.
Zhigang Wu, Yue Zhao, Yizhou Peng, Pengcheng Liu, Qixuan Huang, Yang Wo, Yunjian Pan, DongDong Zheng, Chongze Yuan, Yan Shang, Xiao Chen, Hui Hong, Yihua Sun   +12 more
openaire   +2 more sources

Genome‐Wide Association Analysis of Hippocampal Neuroplasticity as an Indicator of Stress Responsiveness in Laying Hens (Gallus gallus domesticus)

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Environmental stressors in commercial poultry systems can negatively affect bird welfare, although individuals vary considerably in their responses. Neuroplasticity within the hippocampus, measured through the density of doublecortin‐positive (DCX+) neurons, provides a potential biomarker of stress experience in laying hens.
Lindsay Neuert, Vern Osborne, Elena A. Armstrong, Fábio Pértille, Carlos Guerrero Bosagna, Timothy Boswell, Tom V. Smulders, Christine F. Baes, Bayode O. Makanjuola   +8 more
wiley   +1 more source

Table2_AhR Antagonist Promotes Differentiation of Papillary Thyroid Cancer via Regulating circSH2B3/miR-4640-5P/IGF2BP2 Axis.xls

, 2021
Abnormally high expression of aryl hydrocarbon receptor (AhR) has been implicated in dedifferentiation of radioiodine-refractory papillary thyroid cancer (RR-PTC).
Meiliang Guo (11871101), Feng Guan (725911), Ri Sa (11871098), Danyan Liu (11871104)   +3 more
core   +1 more source

IGF2BP2 orchestrates global expression and alternative splicing profiles associated with glioblastoma development in U251 cells

Translational Oncology
Glioblastoma (GBM) is a highly invasive and malignant central nervous system tumor with a median survival duration of 15 months despite multimodal therapy.
Wenqing Liu, Yan Liu, Haoyuan Li, Shixiong Wang, Pengfei Chen, Zhongtao Liu, Xianhao Huo, Jihui Tian   +7 more
doaj   +1 more source

Predictive value of IGF2BP2 for endometrial cancer recurrence: a multicenter study

Frontiers in Oncology
Background Predictive value of IGF2BP2 in combination with clinicopathological parameters for postoperative recurrence in endometrial cancer (EC): development and validation of a prognostic model. Methods This multicenter study ...
Xiong, Jie, Jiang, Peng, Bai, Xue, Tu, Yuan, Tian, Chenfan, Gong, Chunxia, Gong, Yu, Hou, Lamei, Zhao, Limei, Yuan, Rui   +9 more
openaire   +2 more sources

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, Volume 117, Issue 10, Page 2733-2751, October 2026.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source