Results 31 to 40 of about 1,618 (161)

Mathematical Models and Methods for Research and Optimization of Protein Extraction Processes from Chickpea and Curd Whey Solutions by Electroflotation Coagulation Method

Mathematics, 2022
The development of mathematical models and efficient technologies for the processing of protein-containing dairy and vegetable raw materials and the production of food and feed concentrates with controlled functional properties is one of the most ...
Igor Timofeev, Ekaterina Pleshakova, Elena Dogadina, Aleksey Osipov, Azret Kochkarov, Stefan Ignar, Stanislav Suvorov, Sergey Gataullin, Sergey Korchagin   +8 more
doaj   +1 more source

DataSheet1_Bamboo Shark as a Small Animal Model for Single Domain Antibody Production.DOCX

, 2021
The development of shark single domain antibodies (sdAbs) is hindered by the high cost and tediousness of large-sized shark farming. Here, we demonstrated white-spotted bamboo sharks (Chiloscyllium plagiosum) being cultivated commercially as a promising ...
Meiniang Wang (8449773), Limin Feng (239177), Likun Wei (3863683), Naibo Yang (3097908), Jinhua Gong (11808959), Jiajun Wu (430971), Hongming Dong (11808965), Dan Su (8007), Leo Lai Chan (10196041), Haitao Xiang (3549005), M. A. R. Al Azad (11808962), Jiahai Shi (229430), Yuan Jiang (296541)   +12 more
core   +1 more source

Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark

BMC Immunology, 2004
Background Adult cartilaginous fish express three immunoglobulin (Ig) isotypes, IgM, IgNAR and IgW. Newborn nurse sharks, Ginglymostoma cirratum, produce 19S (multimeric) IgM and monomeric/dimeric IgM1gj, a germline-joined, IgM-related VH, and very low ...
Dooley Helen, Lohr Rebecca L, Rumfelt Lynn L, Flajnik Martin F   +3 more
doaj   +1 more source

Difficult-to-express shark IgNAR antibody produced in CHO cells: production bottleneck identification and a trial for productivity enhancement [PDF]

Difficult-to-express shark IgNAR antibody produced in CHO cells: production bottleneck identification and a trial for productivity enhancement
呂, 小芳, リュー, シャウファン, Lyu, Xiaofang   +2 more
core   +4 more sources

Mapping the effectiveness of nature‐based solutions for climate change adaptation

Global Change Biology, Volume 26, Issue 11, Page 6134-6155, November 2020., 2020
We present the first global systematic map of the effectiveness of nature‐based solutions (NbS) for addressing the impacts of climate change and hydrometeorological hazards on people. We found that most studies on NbS interventions in natural or semi‐natural ecosystems reported reduced climate impacts and that, overall, more synergies than trade‐offs ...
Alexandre Chausson, Beth Turner, Dan Seddon, Nicole Chabaneix, Cécile A. J. Girardin, Valerie Kapos, Isabel Key, Dilys Roe, Alison Smith, Stephen Woroniecki, Nathalie Seddon   +10 more
wiley   +1 more source

Efficient Construction and Effective Screening of Synthetic Domain Antibody Libraries

Methods and Protocols, 2019
Phage display is a powerful technique for drug discovery in biomedical research in particular for antibody libraries. But, several technical challenges are associated with the selection process.
Arghavan Solemani Zadeh, Alissa Grässer, Heiko Dinter, Maximilian Hermes, Katharina Schindowski   +4 more
doaj   +1 more source

Remotely Sensed Land Surface Temperature-Based Water Stress Index for Wetland Habitats

Remote Sensing, 2020
Despite covering only 2−6% of land, wetland ecosystems play an important role at the local and global scale. They provide various ecosystem services (carbon dioxide sequestration, pollution removal, water retention, climate regulation, etc.) as ...
Wojciech Ciężkowski, Sylwia Szporak-Wasilewska, Małgorzata Kleniewska, Jacek Jóźwiak, Tomasz Gnatowski, Piotr Dąbrowski, Maciej Góraj, Jan Szatyłowicz, Stefan Ignar, Jarosław Chormański   +9 more
doaj   +1 more source

Anti‐ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen‐Induced Mouse Model of Rheumatoid Arthritis

Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its sole ligand, the inducible T cell costimulatory ligand (ICOSL; also known as B7‐related protein‐1 ...
Ronan O’Dwyer, Marina Kovaleva, Jiquan Zhang, John Steven, Emma Cummins, Deborah Luxenberg, Alfredo Darmanin-Sheehan, Miguel F. Carvalho, Matthew Whitters, Kenneth Saunders, Caroline J. Barelle, Ilaria Roato   +11 more
wiley   +1 more source

Coevolution of Mucosal Immunoglobulins and the Polymeric Immunoglobulin Receptor: Evidence That the Commensal Microbiota Provided the Driving Force

International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Immunoglobulins (Igs) in mucosal secretions contribute to immune homeostasis by limiting access of microbial and environmental antigens to the body proper, maintaining the integrity of the epithelial barrier and shaping the composition of the commensal microbiota.
Charlotte S. Kaetzel, M. C. Béné, J. L. Stafford   +2 more
wiley   +1 more source

Rational Design of Single‐Domain Antibodies Targeting the Central Nervous System Neurite Outgrowth Inhibitor Nogo‐A

Applied Research, Volume 4, Issue 3, June 2025.
The development of a nanobody for Nogo‐A, a potent neurite outgrowth inhibitor crucial in multiple sclerosis, is reported using a rational design approach. The nanobody targets the Nogo‐A ectodomain at the S1PR2 receptor‐binding region with submicromolar KD.
Vaidehi Roy Chowdhury, Alexander Röntgen, Matthew Greenig, Yanira Méndez Gómez, Sebastian P. Spiegel, Magdalena Nowinska, Aubin Ramon, Pietro Sormanni, Andrew Chan, Michele Vendruscolo   +9 more
wiley   +1 more source