Results 41 to 50 of about 80,108,489 (239)

IL-7 treatment augments and prolongs sepsis-induced expansion of IL-10-producing B lymphocytes and myeloid-derived suppressor cells [PDF]

, 2018
Immunological dysregulation in sepsis is associated with often lethal secondary infections. Loss of effector cells and an expansion of immunoregulatory cell populations both contribute to sepsis-induced immunosuppression.
Christoph Herrmenau, Stephanie J. Win, Stephanie J Win, Michael Bauer (115390), Stephanie J. Win (4872166), Michael Bauer, Thomas Kamradt, Upasana Kulkarni, Upasana Kulkarni (502494), Christoph Herrmenau (4872163), Thomas Kamradt (12585)   +10 more
core   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

IL-7/IL-7 receptor system regulation following IL-2 immunotherapy in HIV-infected patients

, 2004
Interleukin-2 (IL-2) and IL-7 are the most intriguing molecules in immune-based HIV infection treatment. An in vitro IL-2/IL-7 cross-talk due to IL-2-driven IL-7 receptor-alpha-chain (IL-7R alpha) down-modulation, potentially blocking IL-7 signalling has
M. Clerici, M. Moroni, G. Taskaris, L. Gazzola, F. Franzetti, L. Meroni, M. Galli, A. Gori, C. Molteni, G. Marchetti   +9 more
core   +2 more sources

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-γ, IL-4, IL-5 and IL-10 with age [PDF]

, 2007
Background The rate of development of parasite-specific immune responses can be studied by following their age profiles in exposed and infected hosts. This study determined the cytokine-age profiles of Zimbabweans resident in a Schistosoma haematobium ...
Mduluza Takafira, Taylor, Matthew, Georgina Winborn, Mutapi, Francisca, Maizels, Rick M, Midzi, Nicholas, Winborn, Georgina, Nicholas Midzi, Mduluza, Takafira, Midzi Nicholas, Mutapi Francisca, Rick M Maizels, Francisca Mutapi, Matthew Taylor, Maizels Rick M, Winborn Georgina, Taylor Matthew, Takafira Mduluza   +17 more
core   +2 more sources

Evaluation of IL-2 and IL-7 expression in patients with prostate cancer

Research in Molecular Medicine, 2019
Background: Prostate cancer is a biologically heterogeneous disease which has become the fifth leading cause of cancer-related deaths in men worldwide. Interleukins (ILs) display required inflammation moderator.
Faezeh Namazi, Nasrin Hadi, Fatemeh Parnian, Mansour Moghimi   +3 more
doaj  

Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica

Biology
China’s livestock industry grapples with challenges posed by infectious diseases and the misuse of antibiotics, resulting in a heightened risk of drug-resistant pathogens.
Junjie Peng, Linhan Zhang, Jiangling Li, Xuebin Lv, Rui Liu, Jianlin Chen, Gang Wang, Rong Gao   +7 more
doaj   +1 more source

POSSIBLE MECHANISMS OF STIMULATORY EFFECTS OF MESENCHYMAL STROMAL CELLS UPON T CELL RECOVERY DURING CHEMOTHERAPY-INDUCED LYMPHOPENIA

Медицинская иммунология, 2014
The aim of present work was to evaluate the effect of mesenchymal stromal cells (MSCs) from lymphoma patients on the in vitro and in vivo homeostatic proliferation of lymphocytes.
E. V. Batorov, E. Ya. Shevela, M. A. Tikhonova, N. V. Pronkina, D. S. Batorova, I. V. Kryuchkova, T. I. Pospelova, A. A. Ostanin, E. R. Chernykh   +8 more
doaj   +1 more source

Closing the Loop on LIB Waste: A Comparison of the Current Challenges and Opportunities for the U.S. and Australia towards a Sustainable Energy Future

Recycling, 2023
Many countries have started their transition to a net-zero economy. Lithium-ion batteries (LIBs) play an ever-increasing role towards this transition as a rechargeable energy storage medium.
Gavin E. Collis, Qiang Dai, Joanne S. C. Loh, Albert Lipson, Linda Gaines, Yanyan Zhao, Jeffrey Spangenberger   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source